KEGG   Nonomuraea coxensis: Nocox_13350
Entry
Nocox_13350       CDS       T07466                                 
Symbol
nocA
Name
(GenBank) A50926 NRPS, modules 1-2
  KO
K16428  nonribosomal peptide synthetase CepA
Organism
ncx  Nonomuraea coxensis
Pathway
ncx01055  Biosynthesis of vancomycin group antibiotics
Brite
KEGG Orthology (KO) [BR:ncx00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01055 Biosynthesis of vancomycin group antibiotics
    Nocox_13350 (nocA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins [BR:ncx01008]
    Nocox_13350 (nocA)
Polyketide biosynthesis proteins [BR:ncx01008]
 Nonribosomal peptide synthetase (NRPS)
  Linear NRPS
   Vancomycin synthetase
    Nocox_13350 (nocA)
SSDB
Motif
Pfam: AMP-binding Condensation PP-binding AMP-binding_C
Other DBs
NCBI-ProteinID: QYC40287
LinkDB
Position
2850084..2856365
AA seq 2093 aa
MSATPTVPDLFARQVERTPDAVALTDGDRVLTYRRLDELSGALSGRLIGRGVRRGDRVAV
MMDRSADLVVTLLAVWKAGAAYVPVDAAHPPRRVAFMVADSGISLMVFSAATRDAVPEGV
ESIEFTGEGVGGTPAVTVGPGDLAYVMYTSGSTGTPKGVAVPHRSVAELAGNPGWGMEPG
DAVLMHAPYTFDASLFEIWVPLVSGARVVIAAPGPVDARRLREAVAAGVTKAHLTAGSFR
AVAEESPESFADLREVLTGGDVVPAYAVERVRAACPRARIRHLYGPTETTLCATWHLLEP
GDAAGPVLPIGRPLPGRRARVLDASLRPVEPGVVGDLYLSGAGLADGYLDRPGLTAERFV
ADPSAPGRRMYRTGDLAQWSADGELLFAGRADDQVKIRGFRIEPGEVEAALTAQPNVREA
VVGAVDGRLIGYVVADGDVDPVLVREGLAASLPEYMVPAALVTLDTLPLTGSGKVDRRAL
PAPGFAPSATRREPGTDAERVLCDMYAELLRPEGRRVGVDDGFVELGGDSIAAIRLAARA
SRAGLLVTPAQIFTERTPARLAAVAGAVPAGRPADGPLITLTAEEEAELRIAVPDAEEVW
PLAPLQEGLYFQATLDDEGHDIYQAQWILELEGPLDAARLRASWEAVFARHAELRVSFHR
RASGKTLQVVAGHVVLPWREVELAGGSDVDAAVETLIRQEQEQRFDLAKAPLFRLVLVRY
GEGRHRLLVVHHHILTDGWSVAVILNEVAEAYTAGGRLPDRAGASTYRDFLAWSDRQDKD
AARAAWRAELSGLDGPAPIARAAATTGAGTEYEHRVAFLRPDLHTGLTELARDHGLTLNT
LAQGAWAMVLARLARRTDVVFGTTVACRPAELPDVESVPGLMMNTVPVRVPLRGGQPVVD
MLRDLQARQTALTPHQHLGLPEIQRAAGHGAVFDTLLVFENYPRDFAGRFTYLGTVEGTH
YPLTLGIIPGDHFRIQLVYRRGQVEESVAESILGWFTSALTAMAADPHGLVGRIGVGEPW
DGGQERARAAGEPLPVLVRRVVEDRPDDVAVVDGDGELSFGGLWERATGLAAELRARGIG
PETRVAVMVGRSAWWAVAVLGVSTAGGAFVPVDPAYPAERVRWILADADPALVLCGGTTR
EAVPEEFGDRLVAVDELDLAGGGDAGSPRVRPDDAAYVIYTSGSTGTPKGVVVTHAGLGN
LAMAQIDRFAVSPSSRVLQFAALGFDAMVSEVLMALLSGARLVMAPERTLPPAVSLAEAL
RRWEVTHVTVPPSVLATADALPAGLETVVVAGEACPPGLANRWSAGLRLVNAYGPTEATV
CAAMSMPLAASRDVVPIGKPIAGGRCYVLDAFLRPVPPGITGELYVAGIGLARGYLGRAA
LSAERFVADPFVVGGRMYRTGDLAYWSGAGELVFAGRDDDQVKIRGYRVEPGEVEAVLAG
QPGVDQAVVVARGGRLLGYVVSGGGVDPVGLRERVAGVLPEYMVPAAVVVLDSVPVTANG
KVDREALPDPGFGGRVSGREPRTEVERALCGLFAEVLGLPGVTAVGPDDSFFELGGDSIT
SMQLAARARREGMRFGAREVFERKTPAGLAAIVGLGGEPAAGPADGVGEIAWTPVMRALG
DGITGSRFAQWVVLGAPPELRVDVLAAGLAAVVDTHDMLRSRVVDDRAGRRLVVGERGSV
DTARLVTRVDGAGRALDEVVERAVREAVERLDPAAGVMAQVVWVDAGPARTGRLALVVHH
LAVDGMSWRILVPDLRLACEAVAEGRDPALEPVWGSFRRWAALLEESALSRERVDELRTW
RTIVGQEDRPIGRRSPNAGRDAAGGVRSRSWVMSGAEASVLVGKVPVAFHCGVHEVLLAG
LAGAVARRHGVHGVLVDVEGHGRHPAGGMDLSRTVGWFTSLHPVRLDVTGIDLAAVPAGG
RAAGELLKVVKEQSRAAPGDGLGYGLLRYLNPGTGPVLAALPSPRIGFNYMGRFVTGDQG
GARAWQPVGRIGGSMDPGMGLPHALECNAVVHDTPEGPELVLTVDWRNDLLEEAEVDGLC
RAWLDMLSGLSRQADDPSAGGHTASDFALLDLDQDEIESFEAIAAELSGGQAS
NT seq 6282 nt   +upstreamnt  +downstreamnt
gtgagcgccacaccgacggtgccggacctcttcgcccggcaggtggagcggacacccgat
gcggtggccctgaccgacggggaccgggtcctgacctaccggcggctggacgagctgtcc
ggagcgctgtccgggcggttgatcggccggggcgttcgccggggcgaccgcgtcgcggtg
atgatggaccgctcggcggacctcgtggtgacgctgctcgccgtatggaaggcgggggcg
gcgtacgtgccggtggatgccgcccatcctccccggcgggtggcgttcatggtggcggat
tccgggatctccctgatggtgttctcggccgcgacgcgcgacgccgtaccggaaggggtc
gagtcgatcgagttcaccggcgagggcgtgggcggcacaccggcggtcacggtgggcccg
ggggacctggcgtacgtgatgtacacgtccggctcgacggggaccccgaagggcgtggcc
gtcccgcaccggagcgtcgcggagctggcgggaaaccccggctggggcatggaacccggc
gacgcggtcctcatgcacgcgccctacaccttcgacgcctccctcttcgagatctgggtg
ccgctggtgtcgggcgcccgtgtggtgatcgccgcgccgggtccggtggacgcccggcgc
ctgcgcgaggcggtcgcggccggggtgacgaaggcgcacctcaccgcgggcagcttccgc
gcggtggcggaggagtcgccggaatcgttcgcggacctccgtgaggtgctgaccggtggt
gacgtggtgcccgcgtacgcggtggaaagggtgcgggcggcctgcccccgcgcgcggatc
cggcacctgtacggcccgacggagacgaccctgtgcgcgacgtggcatctgctggagccg
ggtgacgccgcgggtcccgtcctgccgatcggccggccgcttcccggccgccgggcccgc
gtgctcgacgcgtcactgcggccggtggagcccggtgtggtcggtgacctgtacctttcc
ggcgccggtctggcggacggctacctggaccggccggggctgacggcggagcggttcgtg
gcggatccgtccgcgcccgggaggaggatgtaccggacgggggatctcgcccagtggagc
gccgacggtgagctgctgttcgcgggccgggccgacgaccaggtgaagatccgcggattc
cggatcgagccgggtgaggtcgaggccgcgctgaccgctcagccgaacgtccgcgaggct
gtggtgggggcggtcgacgggcgcctgatcggttacgtggtcgcggacggggacgtggat
cccgtcctggtgcgcgagggtctggcggcgtcgctgccggagtacatggttcccgccgct
ctggtcaccctggacacgttgccgctgaccggcagcggcaaggtggacaggagggcgctg
cccgcgcccggcttcgcgccgtccgcgacgcgccgcgaacccggcaccgacgccgagcgc
gtcctgtgcgacatgtacgccgagctcctccggccggaggggcggcgcgtaggggtcgat
gacggtttcgtcgagctgggcggagactcgatcgccgcgatccggctggcggcgcgcgcc
tccagggcaggtctgctggtgacgcccgcccagatcttcacggagaggactcccgcacgg
ctggcggccgtggcgggcgccgtaccggccggcaggcccgccgacggccccctgatcacc
ctcacggcggaagaggaggcggagctgaggatcgccgtcccggacgccgaggaggtctgg
ccgctcgcaccgctccaggaggggctgtacttccaggcgaccctcgacgacgaggggcac
gacatctaccaggcgcaatggatcctggagctggaggggccgctggacgccgcccggctg
cgggcctcgtgggaagcggtcttcgcccggcacgccgagctccgcgtgagcttccaccgg
cgcgcgtcggggaagacgctgcaggtcgtcgccgggcacgtcgtcctgccgtggcgggag
gtggagctggccggcgggagcgatgtcgacgcggccgtggagaccttgatcaggcaggaa
caggagcagcggttcgacctcgccaaggcaccgctgttccggctggtgctggtccgttac
ggcgagggccggcaccgcctgctggtcgtccaccaccacatcctgaccgacggctggtcg
gtggcggtcatcctcaacgaggtggctgaggcgtacacggccggcggccgtctccccgat
cgcgcgggcgcgtccacctaccgggactttctggcctggtcggaccggcaggacaaggac
gccgcgcgtgcggcctggcgggcggagctgtccggcctcgacgggcccgcgccgatcgcg
agagccgccgccacgaccggcgccgggacggagtacgaacatcgcgtcgccttcttgaga
ccggacctccacacggggctgacggagctggcccgcgaccatgggctgacgctgaacacc
ctggcgcagggcgcgtgggcgatggtgctggcgcggctcgcgcggcggaccgacgtggtc
ttcggcaccacggtcgcctgccgtcccgccgagctcccggacgtggagtcggtgccgggc
ctcatgatgaacacggttccggtccgggtgccgctgcggggcgggcagccggtcgtggac
atgctccgtgacctgcaggcgcggcagacggccctgacaccgcatcagcatctggggctg
ccggagatccagcgggcggcaggacacggcgcggtgttcgacacgctgctggtcttcgag
aactacccgcgggacttcgccggccggttcacctatctggggacggtcgaggggacccac
tatccgctgaccctcggcatcatcccgggagaccacttcaggatccagctcgtctaccgg
cgcgggcaggtcgaggagagcgtcgccgagtccatcctggggtggttcaccagcgctctc
acggccatggccgccgatccgcacgggctggtcgggcggatcggtgtgggggagccctgg
gacggcggccaggaacgggcgagggcggcgggggagccgctgccggtgctggtacggcgg
gtggtggaggaccggccggacgacgtggcggtggtggacggcgacggcgagctgtcgttc
ggagggttgtgggagcgggcgacgggactggcggccgagctgagggcacgcgggatcggg
ccggagacccgggtggccgtgatggtgggaaggtcggcgtggtgggcggtcgcggtgctg
ggcgtgtccacggcgggcggcgcgttcgtgccggtggatccggcgtacccggctgagcgc
gtcaggtggatcctggccgacgccgatcccgcgctggtgctgtgcggtgggacgacgcgg
gaggcggtgccggaggagttcggggatcggctggtggccgtcgacgagctggacctggcg
gggggcggcgacgcgggatcgccgcgggtgcgtcccgatgacgcggcctatgtgatctac
acgtcgggatcgaccgggactccgaagggggtcgtcgtcacacacgcggggctcgggaac
ctggcgatggcacagatcgaccggttcgccgtgtcgccgtcgtcgcgagtcctgcagttc
gcggcgctgggcttcgacgccatggtgtcggaggtgctgatggcgctgctgtcgggggcg
aggctcgtcatggcgccggagcggactctgccaccggcggtgtcgctggccgaggcgctg
cggcgatgggaggtcacgcacgtgacggttccgccgtcggtgctggccaccgccgacgcg
ttgccggccgggctggagacggtggtggtggcgggggaggcctgcccgccgggactggcg
aatcgctggtcggcggggctgcggctggtcaacgcgtacgggccgaccgaggccacggtc
tgcgcggcgatgagcatgccgctggcggcgagccgggacgtggtcccgatcgggaaaccc
atcgccggcggccgttgctatgtgctggacgcgttcctccggccggtgccgccggggatc
accggtgagctgtacgtggccgggatcgggctggcccgcggttatctgggtcgtgcggcg
ttgtcggctgagcggttcgtcgcggatccgttcgtcgtcggtgggcggatgtatcggacg
ggggatctggcgtactggtcgggtgcgggtgagctggtgttcgccgggagggatgacgac
caggtcaagatccgtgggtatcgggtggagccgggtgaggtcgaggcggtgctggcgggg
cagccgggggtggatcaggcggtggtggtggcgcgtggggggcgtctgctgggttatgtg
gtgtcgggtggcggggtggatccggtggggttgcgtgagcgggtcgccggggtgttgccg
gagtacatggtgccggcggcggtggtggtgctggattccgtgccggtgacggcgaacggg
aaggtggatcgggaggcgttgccggatcctggtttcggggggcgggtctcggggcgggag
ccgcgtacggaggtcgagcgggcgttgtgcgggttgttcgccgaggtgctcgggttgccg
ggcgtgacggcggtcggtccggacgacagcttcttcgagctgggcggggactcgatcacc
tcgatgcagctggcggcgcgggctcgccgcgagggaatgcgcttcggcgcgcgggaggtg
ttcgagcgcaagacgcccgcggggctcgcggcgatcgtcggcctgggaggcgagcctgcg
gcaggtccggcggacggcgtgggggagatcgcgtggacgccggtcatgcgggccttgggg
gacgggatcacggggtcgcggttcgcccagtgggtggtgctgggcgcgccgccggagctg
cgggtggacgtgctggccgcgggcctggcggcggtggtggacacgcatgacatgctccgg
tcgcgggtcgtcgacgaccgggcgggccgccggctggtggtcggcgaacgcgggtcggtg
gacaccgccaggctggtcacgcgggtggacggcgccggccgtgcgctggacgaggtcgtg
gaacgcgcggtgcgggaggccgtggagcggttggatccggcagcgggtgtgatggcgcag
gtggtctgggtggacgcggggccggcgcggacggggcggctggcgctcgtggtgcaccat
ctggcggtcgacgggatgtcgtggcggattctggtgcctgacctgcggctggcgtgtgag
gcggtggccgagggacgcgatccggcgctggaaccggtgtgggggtcgttccggcgctgg
gcggctctcctggaggagtcggcgctctcgcgggagcgggtcgatgagctgcgcacgtgg
agaacgatcgtcggtcaggaggatcggccgatcggccggcggagcccgaacgcggggcgt
gacgcggccggcggcgtgcgctcacggtcgtgggtgatgtcgggggccgaggcgtcggtc
ctggtggggaaggtcccggtggcgttccactgcggcgttcatgaggttctgctggcaggg
ctggcgggagcggtggcgcgccggcacggtgtccacggggtcctggtggacgtggagggc
cacgggcgccatccggccggggggatggacctgtcccggacggtgggctggttcacgagc
ctgcatccggtgcgcctggacgtgacggggatcgatctggcggccgtgccggccggtggc
cgagcggccggagagctgctgaaggtggtcaaggagcagtcgcgggcggcgcccggcgac
ggactcggctacgggttgctgcggtatctcaatcccgggacgggcccggtcctggcggcc
ctgccgtcgccgcggatcgggttcaactacatgggccggttcgtcaccggtgaccagggc
ggggcgcgggcgtggcagccggtcgggagaatcggcggctcgatggatccgggcatgggc
ctgccgcacgcgctggagtgcaacgcggtcgtccacgacacgccggagggcccggagctg
gtgctcaccgtggactggcggaacgacctgctggaggaggccgaggtcgacgggctgtgc
cgggcgtggctggacatgttgtccgggctgtcccgccaggcggacgatccctccgcgggc
gggcacaccgcgtccgacttcgccctcctcgaccttgaccaggacgagatcgagagcttc
gaagccatagcggcggaactgtctggaggacaggcatcgtga

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