Neisseria cinerea: NCTC10294_01220
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Entry
NCTC10294_01220 CDS
T06828
Symbol
purH
Name
(GenBank) bifunctional purine biosynthesis protein PurH [includes: phosphoribosylaminoimidazolecarboxamide formyltransferase (AICAR transformylase) and IMP cyclohydrolase(inosinicase; IMP synthetase; ATIC)
KO
K00602
phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:
2.1.2.3
3.5.4.10
]
Organism
ncz
Neisseria cinerea
Pathway
ncz00230
Purine metabolism
ncz00670
One carbon pool by folate
ncz01100
Metabolic pathways
ncz01110
Biosynthesis of secondary metabolites
Module
ncz_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
ncz00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
NCTC10294_01220 (purH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
NCTC10294_01220 (purH)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
ncz04147
]
NCTC10294_01220 (purH)
Enzymes [BR:
ncz01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase
NCTC10294_01220 (purH)
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.10 IMP cyclohydrolase
NCTC10294_01220 (purH)
Exosome [BR:
ncz04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
NCTC10294_01220 (purH)
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
AICARFT_IMPCHas
MGS
Motif
Other DBs
NCBI-ProteinID:
SQF83755
LinkDB
All DBs
Position
1:complement(1231330..1232910)
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AA seq
526 aa
AA seq
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MSSIKRALISLSDKTGAVEFAQTLHKLGVEILSTGGTAKLLADAGVPVIEVADYTGFPEM
LDGRVKTLHPKIHGGILGRRDLDEHVAKMEEHGIGNIDLVCVNLYPFAATIAKPNCTLED
AIENIDIGGPTMVRSAAKNWKHVAIVTDTADFPAIAAELEANNGALSDKTRFNLSRKAFS
HTAQYDGMISNYLTSLSDDVLSGQPQIGEFPSQFNQSWIKVQDMRYGENPHQRAAFYRDI
YPAAGSLSAYKQLQGKELSYNNIADADAAWEVVKSFDAPACVIVKHANPCGVAVAADTLT
AYKLAYATDTTSAFGGIIAFNREVDGETVKQITDNQFMEVLMAPKFTAEALEIAAAKKNV
RVLEVPLEAGANRFELKRVGGGLLVQTPDIHRISRADLKVVSKRQPTEQEWNDLMFVWNV
AKYVKSNAIVFGKGGQTYGIGAGQMSRVDSTRIAARKAQDAGLDLNGACAASDAFFPFRD
GVDVIAEQGIKAIIHPAGSMRDQEVFDAADEHGIAMVVTGVRHFRH
NT seq
1581 nt
NT seq
+upstream
nt +downstream
nt
atgtcttccatcaaacgcgccttgatcagcctgtccgacaagacaggcgcagtcgaattt
gcccaaaccctgcacaaactcggtgtcgaaatcctctctaccggcggtacagcaaagctc
ttggctgatgcaggcgttcccgttatcgaagttgccgactataccggttttcccgaaatg
ctcgacggccgcgtgaaaaccctgcatccgaaaatccacggcggcatcctcggccgtcgc
gatttggatgaacacgtcgccaagatggaagagcacggcatcggcaatatcgacctcgtg
tgcgtcaacctttaccccttcgctgccaccatcgccaaaccaaactgcacactggaagac
gcgattgaaaacatcgacatcggcggcccaaccatggtgcgctctgccgcgaaaaactgg
aaacacgtcgccatcgttaccgacacagccgatttcccggccatcgccgccgaactcgaa
gccaacaacggagcattgagcgacaaaacccgtttcaacctctcacgcaaagcattcagc
cacaccgcccaatacgacggcatgatttccaactacctgacctcgctttcagacgacgtc
ttaagcggccagccccaaatcggcgaattcccaagtcagttcaaccaaagctggattaaa
gtgcaagacatgcgctacggcgagaatccgcaccaacgcgccgcgttctaccgcgatatt
taccctgctgcaggcagcctttccgcctacaaacagctgcaaggcaaagaattgtcttac
aacaatatcgccgatgccgatgccgcatgggaagtcgtcaagtcctttgatgcgccggcc
tgcgtgattgtgaaacacgccaatccgtgcggcgtcgccgttgcagccgataccttgacc
gcctacaaactcgcctacgctaccgacaccaccagcgcgttcggcggcatcatcgccttc
aaccgcgaagtggacggcgaaaccgtcaaacaaattaccgacaaccaatttatggaagtc
ctcatggcgccgaagttcaccgccgaagccctcgaaatcgccgccgccaagaaaaacgtg
cgcgtattggaagtgccgcttgaagcaggtgccaaccgctttgaactcaaacgcgtcggc
ggcggactgttggtacaaacgcccgacatccaccgcatcagccgcgccgatttgaaagtc
gtctccaaacgtcaaccgactgagcaagaatggaacgacctgatgttcgtatggaatgtc
gccaaatacgtcaaatccaacgccatcgtcttcggcaaaggcggccaaacctacggcatc
ggcgcaggccaaatgagccgcgtggacagcacccgcatcgctgcccgcaaagcgcaagat
gcaggtttggacttaaacggcgcatgcgctgcctctgatgccttcttcccgttccgcgac
ggcgtggatgtcattgccgagcagggcatcaaagccatcatccaccccgcaggctccatg
cgcgatcaggaagttttcgatgcggcagacgaacacggcatcgccatggtggtaacgggc
gtgcgccacttccgccattga
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