KEGG   Nocardiopsis dassonvillei: Ndas_0025
Entry
Ndas_0025         CDS       T01248                                 
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit
  KO
K00166  2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:1.2.4.4]
Organism
nda  Nocardiopsis dassonvillei
Pathway
nda00280  Valine, leucine and isoleucine degradation
nda00640  Propanoate metabolism
nda00785  Lipoic acid metabolism
nda01100  Metabolic pathways
nda01110  Biosynthesis of secondary metabolites
nda01210  2-Oxocarboxylic acid metabolism
Module
nda_M00036  Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:nda00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00640 Propanoate metabolism
    Ndas_0025
  09105 Amino acid metabolism
   00280 Valine, leucine and isoleucine degradation
    Ndas_0025
  09108 Metabolism of cofactors and vitamins
   00785 Lipoic acid metabolism
    Ndas_0025
Enzymes [BR:nda01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.4  With a disulfide as acceptor
    1.2.4.4  3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
     Ndas_0025
SSDB
Motif
Pfam: E1_dh DXP_synthase_N TPP_enzyme_C Transketolase_N
Other DBs
NCBI-ProteinID: ADH65477
UniProt: D7B624
LinkDB
Position
1:32374..33459
AA seq 361 aa
MADDRDLLPSEQPVRLLDETGSPVDGAALPFPDRERLLAAYTSLVIGRRVNDQASALVRQ
GRLAVYPSSHGQEACQTGAALALAEGDWLFPTYRDTAAVVARGVDPVQVLTLLKGDWHSG
YDPYAHRVAPQATPLATQLLHAVGVAHAARLRGEDTVVMAMCGDGATSEGDFHEALNFAA
VFRAPVVFFVQNNEYAISVPLARQTAAPSLAHKGVGYGVNAERVDGNDTPAVLAVLDRAV
AAARAGEGPQLVEAHTYRMQAHTNADDATRYRTQEEVDPWEARDPLLRMEAYLTRKRVLT
KARKARIAEDAEAVAAAMREGVTRDTDPEPAELFAHVFATPTPQLDEQAAFLADELSREG
N
NT seq 1086 nt   +upstreamnt  +downstreamnt
atggctgatgaccgggaccttctcccctccgagcagccggtccggctgctcgacgagacc
ggaagcccggtggacggggccgccctgccgttcccggaccgggagcggctgctcgccgcg
tacacctccctggtgatcggccgccgcgtcaacgaccaggccagcgccctcgtgcggcag
ggccgcctggccgtgtacccctcctcgcacgggcaggaggcctgccagacgggcgcggcc
ctggccctggcggagggcgactggctcttcccgacctaccgcgacaccgccgccgtggtc
gcgcgcggggtggacccggtgcaggtgctcaccctgctcaagggcgactggcactcgggc
tacgacccctacgcgcaccgcgtggccccgcaggccacgccgctggccacccagctcctg
cacgcggtgggcgtcgcgcacgccgcccgcctgcgcggtgaggacaccgtggtcatggcg
atgtgcggcgacggcgccaccagcgagggcgacttccacgaggcgctgaacttcgcggcg
gtgttccgggccccggtggtcttcttcgtgcagaacaacgagtacgccatctccgtcccc
ctggcccgccagaccgccgccccctcgctcgcccacaagggcgtcggctacggggtgaac
gcggaacgggtggacggcaacgacacccccgcggtgctcgccgtgctggaccgggccgtg
gccgccgcgcgggcgggcgagggcccccagctcgtggaggcgcacacctaccgcatgcag
gcgcacaccaacgccgacgacgccacccggtaccgcacccaggaggaggtcgacccctgg
gaggcccgcgaccccctgctgcgcatggaggcctacctcaccaggaagcgcgtcctcacc
aaggcccgcaaggcgcgcatcgccgaggacgcggaggccgtggccgccgccatgcgcgag
ggcgtcaccagggacaccgaccccgagcccgccgaactgttcgcgcacgtgttcgcgacc
cccacgccgcagctggacgagcaggccgccttcctggccgacgaactgagcagagagggc
aactga

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