Natator depressus (flatback sea turtle): 141996885
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Entry
141996885 CDS
T11397
Symbol
HSD17B2
Name
(RefSeq) 17-beta-hydroxysteroid dehydrogenase type 2
KO
K13368
17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:
1.1.1.62
1.1.1.239
]
Organism
nds Natator depressus (flatback sea turtle)
Pathway
nds00140
Steroid hormone biosynthesis
nds01100
Metabolic pathways
Module
nds_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
nds00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
141996885 (HSD17B2)
Enzymes [BR:
nds01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.62 17beta-estradiol 17-dehydrogenase
141996885 (HSD17B2)
1.1.1.239 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
141996885 (HSD17B2)
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Motif
Pfam:
adh_short
adh_short_C2
KR
Gpr1_Fun34_YaaH
Motif
Other DBs
NCBI-GeneID:
141996885
NCBI-ProteinID:
XP_074825284
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Position
12:33426925..33453062
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AA seq
393 aa
AA seq
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MDTYISTADPSVLLCLGVTAAFGIITFYKVKKNQVEKKCIFARDLLVLLLLEILCFVTLK
SYVGLILFSMACLICYIYLPVQTMLPVDNKAVLITGSDSGIGHALAKYFDNLGFVVFASV
LNKKGPGAEELKRSCSQRLCVLQLDLTSSSQIKEAYLNISEMVQNTGLWGVVNNAGILGF
TADGELLPMSVYKQCMDVNFFGHVEVTKMFLPLLRKSKGRLINISSMAGGIPMPRFAAYG
ASKAALSMFSGVMRQELAKWGIKVAAVHPAGFRTCIQGTSELWAKQEKHLLENLTPDVKK
DYGEDYIQALKNFLLNMPVHCDSDLSPVLDDVLHALLAKSPHGLYTPGKSAYLGLCTFCY
FPLWFYDFFMGKMQSTKSVPSALKASEAKNKNT
NT seq
1182 nt
NT seq
+upstream
nt +downstream
nt
atggacacttacatctctacagctgacccttctgtcttgctctgcttgggtgtgactgca
gcatttggaataatcaccttttacaaagtcaagaagaaccaggtggagaaaaagtgtata
tttgcccgtgatctccttgtgctacttttattggaaatactctgttttgtcacactgaaa
agttacgtaggcttaatcctgttctctatggcatgtctcatctgttatatttacttacca
gttcaaacaatgttacctgtggataacaaagctgtattgatcacaggaagtgattccggg
attggacatgcattggcaaagtactttgacaatttaggatttgttgtatttgctagtgtc
ttgaataaaaaaggacctggggctgaagaattaaaaagaagctgttcccagagactttgt
gtcctgcagctggatttaaccagttcttcacaaattaaggaagcctatcttaacatttca
gagatggtgcaaaatacagggttatggggtgttgtcaacaatgctggaatcctggggttt
actgcagatggtgagctgctgcccatgagtgtgtacaagcagtgtatggatgtgaatttc
tttgggcatgtagaggtgaccaaaatgttcttaccgttacttcggaaatccaaaggaagg
ctaattaatatatcaagtatggcaggaggcattccgatgccaagatttgccgcatatggt
gcatcaaaagccgctctgtccatgttttctggagtaatgaggcaggagcttgccaaatgg
ggaattaaagttgctgcagttcatccagcaggcttcagaacgtgcatacaaggtacatct
gagctgtgggctaagcaagaaaagcatcttctggagaatctcacaccagatgtgaagaaa
gattatggtgaagactacattcaggcactgaaaaatttcctcctgaacatgccagttcat
tgtgactctgacctctctccagtactagatgatgttctccatgctttattggcaaagagt
ccacatggtttatacactccaggcaaaagtgcttacctaggtctatgtaccttttgctat
tttcctctctggttttatgattttttcatgggtaagatgcaaagtaccaagagtgtaccc
agcgcgttaaaggcatcagaggccaaaaacaagaacacgtag
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