Nocardiopsis exhalans: NE857_01950
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Entry
NE857_01950 CDS
T08285
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
nex
Nocardiopsis exhalans
Pathway
nex00300
Lysine biosynthesis
nex00550
Peptidoglycan biosynthesis
nex01100
Metabolic pathways
nex01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
nex00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
NE857_01950
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
NE857_01950
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
NE857_01950
Enzymes [BR:
nex01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
NE857_01950
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
USY20448
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Position
440438..441826
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AA seq
462 aa
AA seq
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MIPLTAAAVAEATGGRLTAGTDPLLRVTAPASIDSRRVDPGGLFAAIPGRHTDGHDHAQA
AIAAGAALVLASRPVAAPAVQVADVTVALGTLARHVAGQLSATVIGITGSNGKTSTKDLA
AQVLAHHGPVTATDGSYNNELGFPLTVLRATPDTRYLVLEMGARGRGHLGYLCDLVTPHV
GLVLNVGTAHIGQYPDGQAGIAAAKNELVTGLPDADHGGLAVLNADDPLVSAMADRTRAR
PMWWSHHPDPTRVHARDVRLTPDGRAEFTLRTPEGTAPVMLSLTGRHHIGNALAVAATAH
GLGLDTATIAQALTEARPGSAGRMQTIIRNDGITLVHDAYNANPDSMSAALIALTSMTAR
RRIAVLGEMAELGEHAAQAHCHLGVLAAQAALDLLVVVGDDHAALIADAARAACAHLDIV
SVRDARQAHDALHRGLHPGDLVLIKASRAARLEDLVAALNDR
NT seq
1389 nt
NT seq
+upstream
nt +downstream
nt
gtgatacctctgaccgcagccgccgtcgccgaggcgaccggaggtcgcctgaccgccggc
accgaccccctcctacgggtcacggcacccgcgagcatcgactcacgccgggtcgacccc
ggcggcctgttcgccgcgatccccggtcggcacaccgacgggcacgaccacgcccaggcc
gccatcgccgcgggcgcggcgctggtgctcgcctcacggccggtggccgccccggccgtc
caggtcgccgatgtcaccgtcgcgctcggcacgctggcccgccacgtggcgggccagctg
tcggcgaccgtcatcggcatcaccggatcgaacggaaagaccagcaccaaggatctcgcc
gcccaggtgctggcgcaccacggacccgtcaccgccaccgacggttcgtacaacaacgaa
ctcggattccccctcacggtcctgcgcgccacccccgacacgcgctacctcgtcctggag
atgggcgcccggggccgcgggcacctcggctacctgtgcgacctggtcacgccccatgta
ggcctggtgctcaacgtcggcaccgcccacatcggccagtaccccgacggacaggccggg
atcgccgcggccaagaacgaactggtcaccggactccccgacgccgaccacggcggcctc
gccgtcctcaacgccgacgatccgctcgtctcagccatggcggaccgaacccgtgcccgc
cccatgtggtggagccaccaccccgatccgacgcgcgtgcacgcccgcgacgtgcgcctc
accccggacggtcgcgcggaattcaccctgcgcacccccgagggcaccgcgcccgtcatg
ctctcgctcaccggccgacaccacatcggcaacgcactcgccgtcgcggcgaccgcccat
ggcctgggcctggacaccgcgacgatcgcccaagctctgaccgaagcacggcccggatcc
gccggacgtatgcagaccatcatccggaatgacggtattaccctcgtccacgacgcctac
aacgcgaatccggactcgatgtcggccgctctcatcgcactgacctcgatgaccgcgcgt
cgccgcatcgcggtcctgggagagatggccgaactcggagagcacgccgcccaagcccat
tgccacctgggcgtgctcgccgcacaggccgctctcgacctcctggtcgtggtcggcgat
gaccacgccgccctgatcgccgacgccgcccgcgccgcatgcgcccacctcgacatcgtc
tccgtccgtgacgcacggcaggcccacgacgccctccaccgcggccttcaccccggcgac
ctcgtcttgatcaaggcctcccgggccgcccgcctcgaagacctcgtcgccgccctcaac
gaccgctga
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