Nocardiopsis exhalans: NE857_11485
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Entry
NE857_11485 CDS
T08285
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
nex
Nocardiopsis exhalans
Pathway
nex00300
Lysine biosynthesis
nex00550
Peptidoglycan biosynthesis
nex01100
Metabolic pathways
nex01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
nex00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
NE857_11485
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
NE857_11485
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
NE857_11485
Enzymes [BR:
nex01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
NE857_11485
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
USY22168
UniProt:
A0ABY5DGJ9
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All DBs
Position
2565670..2567118
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AA seq
482 aa
AA seq
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MIALTLDRIAEITQTAIGGSARPDAVVDGPVVIDSRQVAPGALFVALSGERVDGHDFAES
AAAAGAVAVLASRPVDAPHLLVDGGDDEVLAALARLARHVAVELSDPARGTAAAEVVGVT
GSSGKTTTKDLIAQVVSGTGPTVAPAGSFNNEIGHPLTVLRADTGTKNLVLEVAARGIGH
IAYLCRVAPPRIGVVLNVGSAHMGEFGGREAIAKAKGELVECLPPGSDRRGEGGVAVLNA
DDPLVRAMHTRTDARVVFYGTAEDAQVRATDVVIGDNGAPSFTLNLRGRTARVELGLVGA
HQVSNALAAAAVADDLGMDIQDIATALGAATPVSRWRMEVTEHRGATLVNDAYNANPESM
RAALTTLGALARDRRSIAVLAHMAELGDDGHAEHESVGELAARTGVAHLVVVGTAAEGIA
VGAERAARQGWWDGETIRVPDAEAAADAVRDRMRTGDVVIVKGSRVAALERVIDLITKGD
VQ
NT seq
1449 nt
NT seq
+upstream
nt +downstream
nt
ttgatcgcgctcacgctcgatcggatcgctgagatcacccaaaccgccatcggcggatca
gcgcgccccgacgccgtcgtcgacggccccgtcgtcatcgattcacgacaggtggcgccc
ggagcgctcttcgtcgccctgagcggtgaacgggtcgacggacacgacttcgccgagtcc
gccgcggcggccggagcggtcgcggtcctggcctcgcgcccggtcgacgccccccacctg
ctggtggacggcggtgacgacgaggtcctagcggccctggcccgtctggcccggcacgtg
gccgtcgaactcagcgaccccgcgcgagggacagccgcggccgaggtcgtgggggtcacc
ggctcctccggcaagaccaccaccaaggacctcatcgcccaggtcgtcagcggcaccgga
cccaccgtggcgcccgccggctcgttcaacaacgagatcggccatccgctcacagtgctc
cgcgccgacaccggcaccaagaacctggtcctggaggtcgccgcccgcggcatcgggcac
atcgcgtacctgtgccgcgtggccccgccccggatcggcgtggtcctcaacgtcggcagc
gcccacatgggcgagttcggcggccgtgaggccatcgccaaggccaagggcgagctggtg
gagtgcctgccgcccggcagcgaccggcgcggcgagggcggcgtggccgtcctcaacgcc
gacgacccgctggtgcgcgccatgcacacgcgcaccgacgcccgcgtggtgttctacggc
accgccgaggacgcccaggtgcgcgccaccgacgtcgtcatcggagacaacggcgccccg
tccttcacgctcaacctgcgcggccgcacggcccgggtcgagctgggactggtcggcgcc
caccaggtcagcaacgcgctggccgccgcggccgtcgccgacgacctcggcatggacatc
caagacatcgccaccgccctcggcgcggcgaccccggtcagccgttggcggatggaggtc
accgaacaccgcggtgccaccctcgtcaacgacgcctacaacgccaaccccgaatcgatg
cgggcggcgctgaccaccctgggcgcgctcgcccgggaccgccggtccatcgcggtgctc
gcccacatggcggagctcggcgatgacggccacgccgaacacgagagcgtgggtgagctg
gccgcccggacgggcgtggcccacctggtcgtggtcggcacggcggccgaagggatcgcc
gtcggcgccgaacgcgccgcacggcaggggtggtgggacggtgagaccatccgggttccc
gacgcggaggcggcagccgacgcggtgcgcgaccggatgcgtacaggagacgttgtcatt
gtgaagggatcgcgcgtggctgcgctcgaaagggtcatcgacctcatcaccaagggtgat
gtccagtga
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