Nocardiopsis exhalans: NE857_24080
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Entry
NE857_24080 CDS
T08285
Name
(GenBank) thiamine pyrophosphate-dependent enzyme
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
nex
Nocardiopsis exhalans
Pathway
nex00280
Valine, leucine and isoleucine degradation
nex00640
Propanoate metabolism
nex00785
Lipoic acid metabolism
nex01100
Metabolic pathways
nex01110
Biosynthesis of secondary metabolites
nex01210
2-Oxocarboxylic acid metabolism
Module
nex_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
nex00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
NE857_24080
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
NE857_24080
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
NE857_24080
Enzymes [BR:
nex01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
NE857_24080
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GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-ProteinID:
USY18371
LinkDB
All DBs
Position
complement(5454643..5455680)
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AA seq
345 aa
AA seq
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MPPEESTGQGAITVAHLAPELTRGLYRDMRTARDLDTEAIALQRQGVFPAYVSVRGQEAA
QVASATALDPARDFVFPTYREMAVALAYGVEMVGYMATHRALWHGGLYDVMGSRFGAINA
VVGGPVPHAVGWAVGERLRGDQGVAMAYFGDGASSEGDVHEAMNFAGVFTAPVVFFCQNN
QWALSVPNERQVAGGSIAARAEGYGMPGVLVDGNDAGAVYAATDEAVQRAREGGGPTVIE
ALTYRVEPHSTSDDPGRYRDEAVADRWRQRDPIDLLRTAMLQAEHADEAFFATVATEAAQ
RAEQIRDGVASAPEPDGSELFTHVFRETTEELTRQHRTWQEEVEL
NT seq
1038 nt
NT seq
+upstream
nt +downstream
nt
atgccacccgaagagtcgacgggccagggcgccatcaccgtggcgcacctggcacccgaa
ctgacccgcggcctctaccgcgacatgcgcaccgcgcgcgacctggacaccgaggccatc
gccctgcagcgccagggcgtcttccccgcctacgtctccgtccgggggcaggaggccgcg
caggtcgccagcgccaccgcgctcgaccccgcccgcgacttcgtcttccccacctaccgc
gagatggccgtcgccctggcctacggcgtcgagatggtcggctacatggccacccaccgc
gccctgtggcacggcggcctctacgacgtcatgggctcccgcttcggcgccatcaacgcc
gtggtcggcggacccgtcccgcacgccgtgggctgggcggtcggtgagagactgcgcggc
gaccaaggcgtggccatggcctacttcggtgacggtgccagctccgagggcgacgtacac
gaggccatgaacttcgccggggtcttcacggcaccggtcgtcttcttctgccagaacaac
cagtgggccctgtcggtgcccaacgaacgccaggtcgcgggcggctccatcgccgcgcgc
gccgagggctacggcatgcccggcgtcctcgtcgacggcaacgacgccggagcggtctac
gcggccaccgacgaggccgtccagcgcgcccgcgagggcggcggacccaccgtcatcgag
gcgctcacctaccgcgtcgaaccccactccacctccgacgaccccggccgctaccgcgac
gaggccgtcgccgaccgctggcgccaacgcgaccccatcgacctgctgcgcaccgcgatg
ctacaggccgagcacgccgacgaggccttcttcgccaccgtcgccaccgaggccgcccag
cgcgccgagcagatccgggacggggtcgccagcgcccccgagcccgacggatccgagctg
ttcacgcacgtcttccgggagaccaccgaggagctgacccggcagcaccgcacctggcag
gaagaggtcgagctgtga
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