Nocardia farcinica IFM 10152: NFA_17620
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Entry
NFA_17620 CDS
T00207
Symbol
murF
Name
(GenBank) putative UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
nfa
Nocardia farcinica IFM 10152
Pathway
nfa00300
Lysine biosynthesis
nfa00550
Peptidoglycan biosynthesis
nfa01100
Metabolic pathways
nfa01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
nfa00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
NFA_17620 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
NFA_17620 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
NFA_17620 (murF)
Enzymes [BR:
nfa01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
NFA_17620 (murF)
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
BAD56608
NIH_Japan:
nfa17620
UniProt:
Q5YYY3
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Position
1917178..1918677
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AA seq
499 aa
AA seq
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MIEMTLREIADVVGGTLHDAPDPEVRVTGTAEFDSRRIGSGDLFLALPGERADGHDYAAA
AVAAGAAAVLAARPVGVPAVVVEPRRCSVPATSMALAHDADGSGAAVLAALAALARASVE
RLSAAGGLTVVGVTGSSGKTSTKDLLAAVLAPLGPVVAPPGSFNNELGHPWTALRATADT
RFLVLEMSARGVGHIAALAEVAPPRIGVVLNVGTAHLGEFGSREAIARAKGELVEALPAD
GLAILNADDPNVAAMAARTAARVVRVGLSGDADYRASEVRLDEQARATFTLHTPAGSTEI
RLGVHGEHQVGNALAAAAVASECGADLATVAAALSGARAVSERRMDVRTTADGVTVVNDS
YNANPDSVRAALKALVTMSRAGERPRRSWAVLGEMAELGEESVLEHDGIGRLAVRLDVDR
LVVVGTGRPSRAMHQGAVMEGSWGEESVLVPDIDAAVALLDREVEPGDVVLVKASKSVGL
WEVAEHLTRRAGSDTEAAQ
NT seq
1500 nt
NT seq
+upstream
nt +downstream
nt
atgatcgagatgacactgcgggagatcgcggacgtcgtcggcggcacgctgcacgacgct
cccgacccggaggtgcgagtgaccggtacggccgaattcgattcgcgccgcatcggttcg
ggggatctgttcctcgccctgcccggtgaacgggccgacgggcacgactacgccgccgcg
gcggtggccgccggtgcggccgcggtgctggcggcgcgaccggtgggcgtgcccgcggtg
gtggtcgaaccacggcggtgcagtgtgccggccacgtcgatggcgctggcgcacgacgcc
gacggctccggcgccgcggtactcgccgcgctggccgcgttggcccgcgccagcgtcgaa
aggctcagcgccgccggtggtctcaccgtcgtcggggtgaccggctcgtccggcaagacc
tccaccaaggatctgctcgccgccgtgctcgcgccgctcggcccggtcgtcgcgccgccc
ggctcgttcaacaacgagctcggccacccctggacggcgttgcgcgccaccgccgacacc
cgcttcctggtgctggagatgtccgcccgcggtgtcgggcacatcgccgcgctggccgag
gtcgcgccaccgcgcatcggcgtggtgctcaacgtcggcaccgcccacctcggcgagttc
ggcagccgcgaggccatcgcccgcgccaagggcgaactggtcgaagcgctgcccgccgac
gggctcgcgatcctcaacgccgacgacccgaacgtggcggccatggccgcgcgcacggcc
gcgcgggtggtccgcgtcggtctgtccggcgacgccgactaccgcgcgagcgaggtccgc
ctcgacgagcaggcacgtgccaccttcaccctgcacacccccgcgggcagcaccgagatc
cggctcggcgtgcacggcgaacaccaggtcggcaatgcgctcgccgccgccgcggtggcg
agcgaatgcggcgccgatctcgccaccgtcgccgcggcgttgtccggcgcccgcgcggtg
tccgaacgccggatggacgtgcggaccaccgccgacggcgtcaccgtggtcaacgactcc
tacaacgccaaccccgactcggtgcgggccgcgctcaaggcgctggtcaccatgtcccgg
gcgggcgagcggccgcggcgcagctgggcggtgctcggcgagatggccgagctgggcgag
gagtcggtgctcgaacacgacgggatcggcaggctcgcggtgcgtctggacgtcgaccgg
ctggtcgtcgtcggcaccggccgcccctcccgggcgatgcaccagggcgcggtcatggaa
ggctcgtggggcgaggagtcggtgctggtgcccgacatcgacgccgccgtcgcgttgctc
gaccgggaggtcgagccgggtgacgtggtgttggtgaaggcatcgaagtcggtgggcctg
tgggaggtcgccgagcatctgacccgccgggcgggcagcgacacggaggcggcgcagtga
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