Nocardia farcinica IFM 10152: NFA_30390
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Entry
NFA_30390 CDS
T00207
Symbol
leuA2
Name
(GenBank) putative 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
nfa
Nocardia farcinica IFM 10152
Pathway
nfa00290
Valine, leucine and isoleucine biosynthesis
nfa00620
Pyruvate metabolism
nfa01100
Metabolic pathways
nfa01110
Biosynthesis of secondary metabolites
nfa01210
2-Oxocarboxylic acid metabolism
nfa01230
Biosynthesis of amino acids
Module
nfa_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
nfa00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
NFA_30390 (leuA2)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
NFA_30390 (leuA2)
Enzymes [BR:
nfa01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
NFA_30390 (leuA2)
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Motif
Pfam:
HMGL-like
IPMS_D2
Motif
Other DBs
NCBI-ProteinID:
BAD57886
UniProt:
Q5YVA5
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All DBs
Position
complement(3225601..3227343)
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AA seq
580 aa
AA seq
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MSATAFPTLSTPAGEIPATAPAWNRQRRSQMPSHRYRDVHSRVAVPLTDRQWPTRRLTEA
PLWVPVDLRDGNQALAEPMDPARKRRFFELLVAMGYKEIEVGYPSASQTDFDFVRLLADT
DLAPDDVTVVVFTPARRDLIERTVESIRGITNPVVVHMYTATAPTWREVVLGHDRAALRA
LILDGGREVLRCAGDLPTVRFEFSPEVFNLTEPDFVLEICDAMTELWQATPQRPVILNLP
ATVEVATPNVYADQIEYMHRNLARRDSVILSVHPHNDRGTGIACAELAVLAGAQRVEGCV
FGNGERTGNVDIATLALNLHAQGVDPMIDFSDIDEIRRTVEYCNRVEIHARHPYVGDLVH
TAFSGTHQDAIKKGLAEHRARAAARGVPEREIDWRVPYLPIDPADIGRSYDAVIRVNSQS
GKGGIAYLLESEYGTVLPRRLQIDFARHVQQHTDDTGREVTAAELWSLFSAVYLREGEAD
APQADLGNRLGIDGVVASGASAAELGAALRRHGVELEVLAVHHTTVTGELLALVEYRDGA
GVRWSAGRGRTAGEAVGNAVAAAVGPATAPARAVAEVRPG
NT seq
1743 nt
NT seq
+upstream
nt +downstream
nt
atgtccgccaccgcgtttcccaccctgtccacgcccgccggggagatccccgcgaccgcg
cccgcctggaatcgccagcgacgctcgcagatgccctcgcaccgctaccgcgatgtccac
tcccgtgtcgcggtaccgctgaccgaccggcagtggcccacccgccggttgaccgaggcg
ccgctgtgggtgccggtcgatctgcgcgacggcaaccaggcactcgccgagccgatggac
cccgcccgcaagcggcgattcttcgaactgctcgtcgcgatgggctacaaggagatcgag
gtcggctacccgtcggcctcgcagaccgacttcgacttcgtccgcctcctcgccgacacc
gacctcgccccggacgacgtcaccgtcgtcgtcttcaccccggcccggcgcgacctgatc
gagcgcacggtcgagtccatccgcggcatcaccaatccggtggtggtgcacatgtacacc
gcgaccgcacccacctggcgcgaggtcgtgctcggccacgaccgcgcagcactgcgcgcg
ctgatcctcgacggcggccgcgaggtgctgcgctgcgcgggcgacctgcccactgtgcgt
ttcgagttctcgccggaggtcttcaatctcaccgaaccggatttcgtgctggagatctgc
gacgcgatgaccgagctgtggcaggccaccccgcagcgtccggtgatcctgaacctgccc
gccaccgtcgaggtcgccacccccaacgtctacgccgaccagatcgaatacatgcaccgc
aacctcgcccgtcgcgacagcgtcatcctctcggtgcacccgcacaacgaccgcggcacc
ggcatcgcgtgcgcggaactcgcggtgctcgccggcgcacaacgggtggagggctgcgtg
ttcggcaacggcgagcgcaccggcaacgtcgacatcgccaccctggcgctgaacctgcac
gcccagggcgtcgacccgatgatcgacttctccgacatcgacgagatccgccgcaccgtc
gaatactgcaaccgcgtcgaaatccacgccaggcacccctatgtcggcgacctggtgcac
accgcgttcagcggcacccaccaggacgccatcaagaagggactggccgagcatcgggcg
cgagcggccgcccgcggtgttcccgaacgcgagatcgactggcgggtaccgtatctgccg
atcgacccggccgacatcggccgcagctacgacgcggtgatccgggtcaactcccagtcc
ggcaagggcgggatcgcctacctgctggagtcggaatacggcacggtgctgccgcggcgg
ttgcagatcgatttcgcccgccacgtccagcagcacaccgacgacaccggacgggaggtg
acggcggcggaactgtggtcgctgttcagcgcggtgtacctgcgcgagggggaagcggat
gcgccgcaggccgatctgggcaatcggctcggcatcgacggggtggtcgcctccggggcg
agcgcggcggagctgggcgcggcactgcggcggcacggcgtcgagctcgaggtactcgcc
gtgcaccacaccaccgtgacgggcgagctgctggcgttggtcgaatatcgcgacggcgcg
ggcgtgcgatggtcggcgggccgtggccgcacggcgggcgaggcggtggggaacgccgtg
gcggccgcggtgggcccggccaccgcaccggcgcgcgccgtcgccgaggtccggccgggc
tga
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