Nocardia farcinica IFM 10152: NFA_3080
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Entry
NFA_3080 CDS
T00207
Symbol
leuA
Name
(GenBank) putative 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
nfa
Nocardia farcinica IFM 10152
Pathway
nfa00290
Valine, leucine and isoleucine biosynthesis
nfa00620
Pyruvate metabolism
nfa01100
Metabolic pathways
nfa01110
Biosynthesis of secondary metabolites
nfa01210
2-Oxocarboxylic acid metabolism
nfa01230
Biosynthesis of amino acids
Module
nfa_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
nfa00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
NFA_3080 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
NFA_3080 (leuA)
Enzymes [BR:
nfa01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
NFA_3080 (leuA)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
HMGL-like
IPMS_D2
LeuA_dimer
Motif
Other DBs
NCBI-ProteinID:
BAD55150
UniProt:
Q5Z341
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All DBs
Position
complement(322994..324787)
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AA seq
597 aa
AA seq
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MSPADAYVSGSRHITAPSKPAPADQPAWNAQKNSSMPAYRYRPFAEEVEPVTLPDRTWPD
KVIDRAPGWCAVDLRDGNQALIDPMSPARKRRMFDLLVRMGYKEIEVGFPSASQTDYDFV
REIIEDNAIPDDVTIQVLTQCRPELIERTFEACAGAANVIVHFYNSTSILQRRVVFRADR
EQVKKIATDAAKLCLEVEKRYPDTNWRYEYSPESYTGTELEYAREVCDAVSEIIAPTPEK
PLIINLPATVEMATPNVYADSIEWMSRNLARRESIVLSLHPHNDRGTAVAAAELGYQAGA
DRIEGCLFGNGERTGNVCLVTLGMNMFSRGIDPQIDFSDIDEIRRTVEYCNQLPVHERHP
YGGDLVYTAFSGSHQDAINKGLDAMKAAADAQNADVSDIVWEVPYLPIDPKDVGRTYEAV
IRVNSQSGKGGVAYIMKTDHGLVLPRRLQIEFSQVVQKITDGEGGEVTPKEMWDVFHEEY
LAPIRPLERIRQKVTAAETDGGVDSITAVVKVDGVEQEITGQGNGPLAAFVDAIATVGYD
VRVLDYSEHAMSAGDDAQAAAYVECAIGDKVVWGVGIATSITTASLRAVVSAVNRAH
NT seq
1794 nt
NT seq
+upstream
nt +downstream
nt
atgtcccccgctgacgcctacgtatccggctcgcgccacatcaccgctccgtcgaagccg
gcccccgccgaccagcccgcctggaacgcgcagaagaactcctcgatgcctgcctaccgg
taccggccgttcgccgaggaggtcgagcccgtcacgctgcccgaccgcacctggcccgac
aaggtcatcgatcgcgcgcccggctggtgcgcggtggacctgcgcgacggcaaccaggcg
ctgatcgacccgatgagcccggcccgcaagcgccgcatgttcgatctgctggtgcggatg
ggctacaaggagatcgaggtcggtttcccctcggccagccagaccgactacgacttcgtg
cgcgagatcatcgaggacaacgcgatccccgacgatgtcacgatccaggtgctgacccag
tgtcgccccgagctgatcgagcgcaccttcgaggcgtgcgcgggcgcggccaacgtgatc
gtgcacttctacaactcgacctccatcctgcagcgccgggtggtgttccgcgccgaccgc
gagcaggtgaagaagatcgccaccgacgcggcgaagctgtgcctggaggtggagaagcgc
taccccgacaccaactggcgctacgaatacagcccggagtcctacaccggcaccgagctg
gagtacgcgcgggaggtgtgcgacgcggtgtcggagatcatcgcgccgacgccggagaag
ccgctgatcatcaacctgcccgccaccgtcgagatggcgaccccgaacgtctacgccgat
tcgatcgagtggatgagccgcaacctggcccgtcgtgaatcgatcgtgctgtcgctgcac
ccgcacaacgatcgcggcaccgcggtggccgcggccgagctgggctaccaggcgggcgcc
gaccgcatcgagggctgcctgttcggcaacggtgagcgcaccggcaacgtctgcctggtg
acgctgggcatgaacatgttctcccggggcatcgacccgcagatcgacttctccgacatc
gacgagatccggcgcacggtcgagtactgcaaccagctgcccgtgcacgagcgccacccc
tacggcggcgacctggtgtacaccgcgttctccggcagccaccaggacgccatcaacaag
ggcctggacgcgatgaaggccgccgcggacgcgcagaacgccgacgtctccgacatcgtc
tgggaggtgccctacctgccgatcgacccgaaggacgtggggcgcacctacgaggccgtc
atccgggtgaactcgcagtccggcaagggcggcgtcgcctacatcatgaagaccgaccac
ggcctggtgctgccgcgccggctgcagatcgagttctcccaggtggtgcagaagatcacc
gacggcgagggcggcgaggtcaccccgaaggagatgtgggacgtcttccacgaggagtac
ctggccccgatccggccgctggagcggatccggcagaaggtgaccgcggccgagaccgac
ggcggcgtcgactcgatcaccgcggtggtcaaggtcgacggtgtcgagcaggagatcacc
ggccagggcaacggcccgctcgcggcgttcgtcgacgccatcgcgaccgtcggctacgac
gtgcgggtgctggactactccgagcacgcgatgtccgccggtgacgacgcgcaggcggcc
gcctacgtcgagtgcgcgatcggcgacaaggtggtctggggcgtcggtatcgccacgtcg
atcaccaccgcctcgctgcgcgcggtcgtctccgcggtcaaccgggcacactga
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