KEGG   Nocardioides faecalis: KG111_01930
Entry
KG111_01930       CDS       T09118                                 
Name
(GenBank) uroporphyrinogen-III synthase
  KO
K13542  uroporphyrinogen III methyltransferase / synthase [EC:2.1.1.107 4.2.1.75]
Organism
nfc  Nocardioides faecalis
Pathway
nfc00860  Porphyrin metabolism
nfc01100  Metabolic pathways
nfc01110  Biosynthesis of secondary metabolites
nfc01120  Microbial metabolism in diverse environments
nfc01240  Biosynthesis of cofactors
Module
nfc_M00846  Siroheme biosynthesis, glutamyl-tRNA => siroheme
nfc_M00926  Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:nfc00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00860 Porphyrin metabolism
    KG111_01930
Enzymes [BR:nfc01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.107  uroporphyrinogen-III C-methyltransferase
     KG111_01930
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.75  uroporphyrinogen-III synthase
     KG111_01930
SSDB
Motif
Pfam: HEM4 TP_methylase Radical_SAM Transferase
Other DBs
NCBI-ProteinID: QVI59167
LinkDB
Position
432395..434065
AA seq 556 aa
MTRATTAKAAPSPAADQLRPGGVSFVGTGPGDPDLLTVRAVRLIQDAEVIITEEPAHVTL
VEVVRARALAAGEIAEDAAEVEIIDGGFGEDGQPLTHAARAKVVVKQAKRAARVVRLLGG
DPFLYASGPEEAQAVAKAGLGFEVVPGVSSVSAVPAYAGIPLTTKDNREVAVVTCGDKVD
WKRYLDFPTLVLLSAVGQIGDIAKQLIELGRSPQTPVAMTRVGTTTEQQTVTSTLERIAA
DARAARIAPPAITVIGSVVDLREKLSWFETKPLFGWRVLVPRTKEQSASLSNRLREFGGV
PEEVPTISVEPPRNPQQMDKAVRGLVEGRYEWIAFTSVNAVKAVREKFEEYGLDARAFSG
LKIAAVGDKTAQAIAAWGLRADLVPSGEQSAAGLLEDWPEYDEQLDPINRVFLPRADIAT
ENLVAGLIDLGWECDDVTAYRTVRAAPPPAPTRDAIKTGKFDAVVFTSSSTVRNLVGIAG
KPHPSTVIAVIGPATAKTAEEHGLRVDVMAPKPDVDLLVEALAGFGAARRAAMVEAGEPV
TKPSDRKPSARRRRAE
NT seq 1671 nt   +upstreamnt  +downstreamnt
atgacgcgagccacgacagccaaggctgccccgtctcccgccgccgaccagctcaggccc
ggtggggtctccttcgtgggcacgggtccgggcgacccggacctgctcaccgtgcgtgcc
gtgcggctcatccaggacgccgaggtgatcatcaccgaggagcccgcccacgtgacgctc
gtcgaggtcgtccgcgcccgcgctctcgccgccggtgagatcgccgaggacgccgccgag
gtcgagatcatcgacggcggcttcggtgaggacggccagccgctgacccacgcggcccgc
gccaaggtggtcgtcaagcaggccaagcgagccgctcgggtggtgcggctgctgggcggc
gaccccttcctctacgcctcgggccccgaggaggcgcaggcggtggcgaaggccggcctc
ggcttcgaggtcgtccccggcgtgtcgtcggtctccgcggtcccggcctacgccggcatc
ccgctgaccaccaaggacaaccgcgaggtggccgtggtcacctgcggcgacaaggtcgac
tggaagcgctacctcgacttcccgaccctggtgctgctctccgcggtcggccagatcggc
gacatcgccaagcagctgatcgagctcggccgctctccgcagaccccggtcgcgatgacc
cgcgtcggcaccaccaccgagcagcagaccgtcacctcgacgctcgagcggatcgccgcg
gacgcccgtgcggcccgcatcgccccgccggcgatcaccgtcatcggctcggtggtcgac
ctgcgcgagaagctgtcctggttcgagaccaagccgctgttcggctggcgtgtgctggtg
ccccgcaccaaggagcagtccgcctcgctgtccaaccggctgcgcgagttcggcggcgtg
ccggaggaggtcccgacgatctccgtcgagccgccgcgcaacccccagcagatggacaag
gccgtgcgcggactggtcgagggccgctacgagtggatcgccttcacctcggtcaacgcg
gtcaaggcggtgcgtgagaagttcgaggagtacggcctcgacgcgcgtgccttctccggc
ctcaagatcgccgcggtcggcgacaagaccgcccaggcgatcgccgcctggggcctgcgg
gccgacctggtgccctccggcgagcagtccgccgccggcctgctcgaggactggcccgag
tacgacgagcagctcgacccgatcaaccgggtcttcctgccgcgtgccgacatcgccacc
gagaacctggtggcgggcctgatcgacctcggctgggagtgcgacgacgtcaccgcctac
cgcaccgtgcgggccgcgccgccgccggcgccgacccgggacgcgatcaagaccggcaag
ttcgacgcggtcgtgttcacctcgtcctcgaccgtgcgcaacctggtcggcatcgccggc
aagccgcacccgtccacggtgatcgccgtgatcggcccggccacggccaagaccgcggag
gagcacggcctgcgtgtcgacgtgatggcgcccaagccggacgtcgacctgctggtcgag
gcgctcgcgggcttcggtgccgcgcgccgcgccgcgatggtcgaggcaggcgagccggtc
accaagcccagcgaccgcaagccctcggctcgccgtcgccgggcggagtga

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