KEGG   Nocardia farcinica NCTC11134: ERS450000_05837
Entry
ERS450000_05837   CDS       T04524                                 
Symbol
cysG_2
Name
(GenBank) Siroheme synthase
  KO
K02302  uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase [EC:2.1.1.107 1.3.1.76 4.99.1.4]
Organism
nfr  Nocardia farcinica NCTC11134
Pathway
nfr00860  Porphyrin metabolism
nfr01100  Metabolic pathways
nfr01110  Biosynthesis of secondary metabolites
nfr01120  Microbial metabolism in diverse environments
nfr01240  Biosynthesis of cofactors
Module
nfr_M00846  Siroheme biosynthesis, glutamyl-tRNA => siroheme
Brite
KEGG Orthology (KO) [BR:nfr00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00860 Porphyrin metabolism
    ERS450000_05837 (cysG_2)
Enzymes [BR:nfr01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.76  precorrin-2 dehydrogenase
     ERS450000_05837 (cysG_2)
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.107  uroporphyrinogen-III C-methyltransferase
     ERS450000_05837 (cysG_2)
 4. Lyases
  4.99  Other lyases
   4.99.1  Sole sub-subclass for lyases that do not belong in the other subclasses
    4.99.1.4  sirohydrochlorin ferrochelatase
     ERS450000_05837 (cysG_2)
SSDB
Motif
Pfam: TP_methylase NAD_binding_7 Pyr_redox 2-Hacid_dh_C CofD Pyr_redox_3
Other DBs
NCBI-ProteinID: CRY84060
UniProt: A0A0H5P8C8
LinkDB
Position
p2:2508438..2509709
AA seq 423 aa
MPNTSDTTEDQVAEPHYLVGLDLRGRRVVVVGGGTVAARRLGLLIAAGADVHVISREVTP
TVEGMASSGQIRVTLRPYADGDLAEAWYAIACTDEPETNAAVVAEAERRRVFCVRADNAR
LGTAVTPATARYEGLTLGVLARGAHRRSAAVRTGLLEALQSGVVADDSVPVTPGVALVGG
GPGDPDLITVRGRRLLARADMVVADRLAPPELLAELGPHVEVVDAAKIPYGRAMAQEAIN
TALVEGAQAGKFVVRLKGGDPYVFGRGYEEVQACVAAGVPVTVVPGVTSPISVPAAAGIP
VTHRGVTHEFVVVSGHVAPDHPDSLVDWSALAQLRGTLVLMMAVERIEQFADALLAGGRP
ADTPAAVVQEGTLRTQRVLRADLGTVAARVRAEGIRPPAIIVIGPTAAFALADIGALTGS
AGQ
NT seq 1272 nt   +upstreamnt  +downstreamnt
gtgccgaacacgtcagacaccaccgaggaccaggtagccgagccgcattatctcgtcgga
ctcgatctgcgcggccgccgcgtcgtcgtggtcggcggcgggacggtcgccgcgcgcagg
ctcgggctgctcatcgccgcgggcgcggacgtgcacgtcatcagccgggaggtgacaccg
accgtcgagggcatggcgagctccggccagatccgggtgacgctgcgcccttacgccgac
ggcgacctcgccgaggcctggtacgccatcgcctgcaccgacgaaccggagaccaacgcc
gccgtcgtcgccgaggccgaacggcgccgggtgttctgcgtgcgcgccgacaacgcccgc
ctcggcaccgccgtcacccccgccaccgcccgctacgagggcctgaccctgggcgtgctg
gcccgcggcgcgcatcgccgctcggccgcggtccgcaccgggctgctcgaggcgctgcaa
tccggtgtggtggccgacgattcggtgccggtcacccccggcgtcgccctcgtcggcggc
ggtcccggtgacccggacctcatcaccgtgcgcggccgcaggctgctggcccgcgccgac
atggtggtcgccgaccggctcgcgccgccggaactactcgccgaactcggcccgcacgtg
gaagtcgtggacgcggcgaagatcccctacggccgggcgatggcgcaggaggcgatcaac
accgcactcgtcgagggcgcccaggcgggcaagttcgtggtgcgactcaagggcggcgac
ccgtacgtgttcggccgcggctacgaggaggtgcaggcctgcgtggcggcgggcgtgccg
gtcaccgtggtgcccggcgtcaccagcccgatctcggtgcccgcggcggcgggcatcccg
gtcacccatcgcggcgtgacgcacgaattcgtcgtcgtcagcggtcacgtcgcgcccgat
caccccgattcgctggtggactggtccgcgctggcgcagttgcgcggcacactcgtgctg
atgatggccgtcgaacgcatcgaacagttcgccgacgcgctgctggcgggcggccgaccg
gccgacaccccggcagcggtcgtccaagagggcaccctgcgcacccagcgcgtgctgcgc
gccgacctcggcacggtcgccgcgcgggtgcgggccgaggggatccggccgcccgccatc
atcgtcatcggaccgaccgccgccttcgcgctcgcggacatcggcgccctcaccggttcg
gccggtcagtag

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