Nothobranchius furzeri (turquoise killifish): 107378360
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Entry
107378360 CDS
T05163
Symbol
tyk2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2 isoform X1
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
nfu
Nothobranchius furzeri (turquoise killifish)
Pathway
nfu04217
Necroptosis
nfu04620
Toll-like receptor signaling pathway
nfu04621
NOD-like receptor signaling pathway
nfu05168
Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:
nfu00001
]
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
107378360 (tyk2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
107378360 (tyk2)
04621 NOD-like receptor signaling pathway
107378360 (tyk2)
09160 Human Diseases
09172 Infectious disease: viral
05168 Herpes simplex virus 1 infection
107378360 (tyk2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
nfu01001
]
107378360 (tyk2)
Enzymes [BR:
nfu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
107378360 (tyk2)
Protein kinases [BR:
nfu01001
]
Non-receptor tyrosine kinases
JAK family [OT]
107378360 (tyk2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
Jak1_Phl
FERM_F1
Kinase-like
SH2
FERM_C_FAK1
Kdo
ABC1
Motif
Other DBs
NCBI-GeneID:
107378360
NCBI-ProteinID:
XP_015804004
UniProt:
A0A1A8VFR2
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All DBs
Position
sgr05:3431365..3442689
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AA seq
1219 aa
AA seq
DB search
MSGKGWSRFFRTGTFPASNGPTQSQGIHVYLFSSEDGEKYLSHTSGDVTAEELCILSAKA
VGITPLCHVLFALYNPQTQCWYSPNQVFTPEENSSLVLHYCMRFYFRNWHGLNEKEPSVF
RYALKSGADEAGSPLLDVKSLEYLFAQSKHEFVNEVVQMEDIESEEELSRFKNESLGMAV
LHLSHHAIQNKSTLQEVAGKIRSLFTLFPPVCLYGKCIFEKQKGKIISVSNGFCYCSVVV
FSLLPWMSLPSFLNCIPRSFAKHLSRDNFLTKIRIRRVFSEFVRTFQQHTVDRGQLGPQE
IMYKYISTLENLAPRFGTETFPVTRLELREDGDGGSSYSNASHGEEASKHSDARPATCEV
MVSGTKGIQWRKIHIQKAQSNPYFRNNYLNYAKKSKHQSSQPNENATDDWTRFCDFPEIT
HIAITDANVCISTQDNHCMEVQMNSNQEARSLISLLDGYYRLTADAHHYLCREVAPPRVV
LSEANLLHGPMHDDFVLHKLKKEAAEEGTFLVRWSALDYHRVILAVLNKNENGSAPNHKQ
FRIQQKGSVFSMDGWDQEFPSVKELTDCLKTFVLKSGPDSFSVRKCCLPKQGEISNLLVK
RQGNEHRTHSRLPLDLTQLRFHQIKDKMIIPKEHLGRGTRTNIYLGHLLVSEDDDDDIEF
NNNMERRKGIHVVLKILEESHKDIALAFFETASLMSQVSHSHLVFVHGVSVKGSENIMVE
EYVEDGPLDVFLRKERTFINAQWKFVVAIQLASALSYLEAKRLVHGNVCAKNILVARSGL
KPNTSPFVKLSDPGIALNVLSREERLDRIPWIAPECVDSDAPIGNAADQWSFGVTLLEIC
NNGDLPMSSCTLSEKECFYQQKGRLAEPSSQELAKFISMCLTYEPDARPSFRTILRDLTE
IMMKNPDISPSGTLAPADPTMFQKRYLKKMRDLGEGHFGKVTLYMYDPSNDGTGELVAVK
ALKQENSDVPDVWKKEIEILKSLYHSNIVRYKGCCTEPGRLEVQLIMEYLPLGSLREFLP
KNKIGVPQCLMFAQQICQGMDYLHSQRYVHRDLAARNVLVENKGLVKIGDFGLTKYIPEG
EIYYRVRETGDSPVYWYAIECLKEMKFSFASDVWSFGVTLYEIFTHCDSRQSPPTKFFEM
MGLTEGSMTLVKIIELLERNRRLPCPRDCPHEARLLMEQCWNKNAENRPSFRTLVDKFDA
LRRMYDWQFNPNFPMSQIC
NT seq
3660 nt
NT seq
+upstream
nt +downstream
nt
atgtctggaaaggggtggtccaggtttttcaggacggggacctttccagcttcaaacggg
cccacccagtcccagggcatccatgtttacctgttctcctctgaagacggggagaagtac
ttgtctcacaccagtggggatgtcaccgctgaagagctgtgcatcttatctgctaaagct
gtggggataacacccctctgccatgtgctgtttgcgctgtataacccacagacccagtgt
tggtacagtccaaaccaggttttcactccagaggagaactccagtctagtccttcactac
tgtatgaggttttactttcggaactggcatggactaaatgagaaggagccttctgtgttc
agatatgctctcaagtctggagcagatgaggctggatcccctctgcttgatgtcaagtcc
ttggagtatttatttgctcagtctaaacacgagtttgtgaatgaagtggtgcaaatggaa
gacatcgagtctgaggaggagctgagtcggttcaaaaacgagagcttgggaatggctgtt
cttcacctctcacaccatgcgatacaaaacaaatccacgttacaagaagtggccggaaaa
atcaggtctttgttcacacttttccccccagtttgtctttatggaaaatgtatatttgaa
aaacaaaaaggcaaaattatatctgtttcaaatggtttttgttattgttccgttgttgtt
ttctctctccttccgtggatgtcccttcccagcttcctaaactgcattccaagatctttt
gccaaacacttatccagagacaactttctgactaaaatcaggatccgtcgggtgttttct
gagtttgtgaggacttttcagcagcacactgtggacaggggtcaactgggtccacaggag
atcatgtacaagtacatctctacccttgaaaacttggctccgcgttttggcacagagact
tttcctgtaactcgcctggagctcagggaggatggggatgggggcagctcctactccaac
gcgagccacggtgaggaggcctcgaaacatagcgacgcgcgtcctgccacgtgtgaagta
atggtgtctggcactaaagggattcagtggaggaagattcacattcagaaggctcagtcg
aatccttacttcaggaacaattacctgaactacgcaaagaaatccaagcatcagtccagc
caaccgaacgagaatgctactgatgattggacccgcttctgtgatttccctgaaataact
cacatagccattaccgatgctaatgtgtgcattagcactcaggacaatcactgcatggag
gtgcagatgaactccaaccaggaggctcgctcccttatctcccttctggacggatactac
cgactgactgccgacgcccaccactacctttgtcgtgaagtggcgccccccagggtcgtg
ctgagtgaggcgaatctgcttcacggacctatgcatgatgactttgtgctgcacaagctg
aaaaaggaggcagcagaggagggaacgttcctcgttcgatggagtgccctcgactaccac
cgcgtcatcctcgctgtgctaaacaaaaacgaaaacggctctgcaccaaaccacaagcag
tttcgtatccagcaaaagggctcggtcttctctatggacggctgggaccaagagttcccc
agcgtcaaggagctcacagattgcctcaaaacctttgtgcttaagtctgggcccgacagc
ttctctgtcagaaagtgctgtttgccaaagcaaggagaaatatccaacctcctggtgaag
agacagggtaacgaacaccgcacccactcacgcttgcccctggacctcacgcagctacgc
ttccaccagatcaaagacaaaatgatcatcccgaaagagcacttggggcgtggcaccagg
actaacatttacttgggtcacttgctggtgtcggaggacgacgacgatgatatcgagttc
aataacaacatggaaaggcgtaaaggcatccacgtggttctgaagattctggaggaaagc
cataaagacattgctctggcatttttcgaaacggcgagtctcatgagccaggtatcccac
agtcacctggtgtttgtgcacggtgtgtctgtcaaaggatccgaaaacatcatggtggag
gagtatgtggaggatgggcctctagatgtcttccttcgtaaagaaaggacattcataaat
gctcagtggaagtttgtcgttgccatacaactcgccagtgccctcagttatcttgaggca
aagcgcctggttcacgggaacgtctgtgccaagaacattctggtggcccggtcagggctg
aaacccaacacttcaccctttgtcaagctgagtgatccaggaattgccttgaatgtcctc
tctagagaagagcgtttggatcgaattccgtggatcgctccagagtgcgttgatagcgat
gcgcctattgggaacgccgctgaccagtggagctttggtgtcacgctgcttgaaatctgc
aacaatggcgatctgcccatgagcagctgcacgttgtctgagaaagagtgtttctatcag
caaaagggtcggctcgctgagccttcctcccaggagctggccaagttcatcagcatgtgt
ttgacatacgagcctgatgcacgaccctcatttcgcaccatcctccgagatctcacagaa
atcatgatgaaaaatcccgatatatcccccagtggaaccctcgcaccggcagaccccacc
atgttccagaaacgctacctgaaaaagatgcgggatttgggagagggacactttgggaag
gtgacgctctacatgtatgacccatccaacgacgggaccggagagcttgtggcggtgaaa
gccttgaagcaggagaacagtgatgtccctgatgtctggaagaaagagatagaaatccta
aaatccctctaccacagtaacatcgtcaggtacaagggctgctgcactgagccagggaga
ctggaagtacagctgatcatggagtaccttcccctggggagtctgcgagagtttcttcct
aaaaataaaatcggtgtgccccagtgcctcatgtttgctcagcagatctgtcagggaatg
gactacctccactcacagcgctatgtgcatcgagatctggcagcccgcaatgtcttagtg
gaaaacaagggtttggtaaagatcggagacttcggtctgacaaaatacatccctgaagga
gagatctactaccgtgttcgggagactggagacagcccggtgtactggtacgccattgag
tgcttgaaggagatgaaattctcttttgcttctgacgtttggtcctttggagttactctg
tacgagatcttcacccactgcgacagccgccagagccccccaactaagttctttgagatg
atggggctaactgaaggatcgatgactctggtgaagatcatagagctgctggagaggaat
cggaggttaccctgtcccagagactgcccccacgaggcgaggttgttgatggagcagtgt
tggaataaaaatgctgaaaaccggccatcattcagaaccctcgtggacaagtttgacgcc
ctacgacgaatgtacgactggcagttcaaccccaacttccccatgtctcagatttgctga
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