Natronobacterium gregoryi: Natgr_0083
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Entry
Natgr_0083 CDS
T02383
Name
(GenBank) 3-isopropylmalate dehydratase, large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
nge
Natronobacterium gregoryi
Pathway
nge00290
Valine, leucine and isoleucine biosynthesis
nge00660
C5-Branched dibasic acid metabolism
nge01100
Metabolic pathways
nge01110
Biosynthesis of secondary metabolites
nge01210
2-Oxocarboxylic acid metabolism
nge01230
Biosynthesis of amino acids
Module
nge_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
nge_M00535
Isoleucine biosynthesis, pyruvate => 2-oxobutanoate
Brite
KEGG Orthology (KO) [BR:
nge00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
Natgr_0083
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
Natgr_0083
Enzymes [BR:
nge01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
Natgr_0083
4.2.1.35 (R)-2-methylmalate dehydratase
Natgr_0083
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Gene cluster
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Motif
Pfam:
Aconitase
AcnX
Motif
Other DBs
NCBI-ProteinID:
AFZ71351
UniProt:
L0ABV2
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Position
81132..82556
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AA seq
474 aa
AA seq
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MSEGTLYDKVWDRHRVTTLPTGQDQLFVGLHLIHEVTSPQAFGMLRERDLEVAYPDLTHA
TVDHIVPTADQSRPYEEDAAEEMMAELEENVREAGIEFSDPDSGDQGIVHVIGPEQGLTQ
PGKTIVCGDSHTSTHGAFGALAFGIGTSQIRDVLATGTVAMEKQKVRKIQVDGELGEGVE
AKDVVLEIIRRLGTEGGVGYVYEYAGEAIENLGMEGRMSICNMSIEGGARAGYVNPDETT
YEWLKETDYFQENPEKFDELEPYWESIRSDEDAEYDDVVHIDANELEPVVTWGTTPGQGI
GIMDPIPAPADLPADKQDTARRAQEHMRVEPGETMDGYEVDVAFLGSCTNARLPDLRRAA
RIVEGREVHDDVRAMVVPGSQRVQEAAEEEGLKDVFEEAGFEWRNAGCSMCLGMNEDQLE
GDEACASSSNRNFVGRQGSKDGRTVLMNPRMVAAAALEGEVTDVRDLPEVEVTA
NT seq
1425 nt
NT seq
+upstream
nt +downstream
nt
atgagcgagggaacgctgtacgacaaggtgtgggaccgccacagggtgacgacgctgccg
accggccaggaccagctgttcgtcggcctccacctcatccacgaggtgaccagtccccag
gccttcggcatgctccgggaacgggacctcgaggtcgcctaccccgacctcacccacgcg
acggtcgaccacatcgtcccgacggccgatcagtcccgaccatacgaggaagacgccgcc
gaggagatgatggccgaactcgaggagaacgtccgcgaagcgggaatcgagttctcggac
cccgacagcggcgaccaggggatcgtccacgtcatcggcccggagcaggggctgacccag
cccggaaagaccatcgtctgtggtgactcacacaccagcacgcacggtgctttcggcgcg
ctcgccttcggcatcggcaccagccagatccgcgacgtgctcgcgacgggcaccgtcgcc
atggagaagcaaaaggtccgaaagatccaggtcgacggcgaactcggcgagggcgtcgag
gcgaaagacgtcgtcctcgagatcatccgccgtctcggtacggagggtggcgtcggctac
gtctacgagtacgccggcgaggccatcgagaacctgggcatggagggccggatgtcgatc
tgtaacatgtccatcgagggcggtgcccgcgcgggctacgtcaaccccgacgagaccacc
tacgagtggctgaaggagacggactacttccaggagaacccggagaagttcgacgaactc
gagccctactgggagtcgatccggtcggacgaggacgcggaatacgacgacgtcgtccac
atcgacgcgaacgaactcgagccggtcgtcacctggggtaccactcccggccagggaatc
ggcatcatggacccgattccggcaccggcggacctgcccgcggacaagcaggacacggcc
cgacgcgcccaggagcacatgcgcgtcgagcccggcgagacgatggacgggtacgaggtt
gacgtcgccttcctcggctcctgtacgaacgcccggctgcccgaccttcggcgggctgcc
cggatcgtcgaggggcgcgaggtccacgacgacgtccgcgcgatggtggttcccggcagt
cagcgcgtccaggaggccgccgaggaggaagggctgaaggacgtcttcgaggaggccggc
ttcgagtggcgcaacgccggctgttcgatgtgtctcggcatgaacgaggaccagctcgag
ggcgacgaggcctgcgcatcgtcgtcgaaccggaacttcgtcgggcgccagggatcgaag
gacggccgcacagtcctgatgaacccgcggatggtcgccgcggcggcgctcgagggtgaa
gtgaccgacgttcgcgacctgccggaagtggaggtgaccgcctaa
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