Natronobacterium gregoryi: Natgr_0087
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Entry
Natgr_0087 CDS
T02383
Name
(GenBank) isocitrate/isopropylmalate dehydrogenase
KO
K00052
3-isopropylmalate dehydrogenase [EC:
1.1.1.85
]
Organism
nge
Natronobacterium gregoryi
Pathway
nge00290
Valine, leucine and isoleucine biosynthesis
nge00660
C5-Branched dibasic acid metabolism
nge01100
Metabolic pathways
nge01110
Biosynthesis of secondary metabolites
nge01210
2-Oxocarboxylic acid metabolism
nge01230
Biosynthesis of amino acids
Module
nge_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
nge_M00535
Isoleucine biosynthesis, pyruvate => 2-oxobutanoate
Brite
KEGG Orthology (KO) [BR:
nge00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
Natgr_0087
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
Natgr_0087
Enzymes [BR:
nge01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.85 3-isopropylmalate dehydrogenase
Natgr_0087
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Motif
Pfam:
Iso_dh
Motif
Other DBs
NCBI-ProteinID:
AFZ71355
UniProt:
L0AE66
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Position
86400..87380
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AA seq
326 aa
AA seq
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MTHEIAVIPGDGIGQEVTPAAVEVLEALEIEFEFREGEAGDAVKEETGEALPQETYDLAA
SADATLFGAAGETAADVILPLREAVDSFVNVRPAKAYPGVDAVRPETDLVFLRENTEGVY
SGHEDRLTDDVATLTRVVTESASRQLAEFACEYVADNDYDGFTTVHKANVMRATDGLFRD
TVAEVADENDIETDEVLMDAFATHVCLEPDQFDVVVCPNLAGDVLSDLAAGLVGGLGLLP
SANVGPDRALFEPVHGTAPDIAGKSVANPAATILSAAMLVEYLGYDEEGAAIREAVETTL
EEGPRTSDLGGDASTGGVTEAIVDRL
NT seq
981 nt
NT seq
+upstream
nt +downstream
nt
atgactcacgagatcgccgtcattcccggcgacggcatcggacaggaggtcacgcccgca
gcggtcgaagtgctcgaggcgctcgagatcgagttcgaattccgcgagggtgaggcgggc
gacgcggtgaaagaggaaactggcgaggcgctgccccaggagacctacgacctcgcggcg
tcggccgacgcgacgctgttcggtgccgccggcgagacggccgccgacgtgatcctcccg
cttcgagaggccgtcgactcgttcgtcaacgttcgaccggcgaaagcgtatcccggggtc
gacgccgttcggcccgagacggacctggtcttcctgcgcgagaacaccgagggcgtctac
tcgggccacgaggaccgcctgaccgacgacgtcgcgacgctgactcgcgtcgtcacggag
tcggcctctcggcaactcgcggagttcgcctgcgagtacgtcgcagacaacgactacgac
ggcttcacgaccgtccacaaagccaacgtcatgcgggcgacggacggcctcttccgggac
acggtcgcggaagtcgccgacgagaacgacatcgagaccgacgaggtactgatggacgcg
ttcgcgacgcacgtctgtctcgagcccgaccagttcgacgtggtcgtttgtccgaacctc
gcgggcgacgtgctctcggatctcgcagcggggctcgtgggaggactcggactcttgccc
tccgccaacgtcggccccgaccgcgcactgttcgaacccgtccacggaactgctcccgac
atcgccggcaagagtgtcgccaacccggcagcgacgattctctcggcggccatgctcgtc
gagtacctcggctacgacgaggagggtgctgccatccgcgaggccgtcgagacgacactc
gaggaggggccgcgcacgtccgacctcggcggcgacgcgtcgaccggcggcgtcaccgaa
gcgatcgtcgaccgcctgtag
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