Nannospalax galili (Upper Galilee mountains blind mole rat): 103724826
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Entry
103724826 CDS
T03372
Symbol
Shmt1
Name
(RefSeq) serine hydroxymethyltransferase 1
KO
K00600
glycine hydroxymethyltransferase [EC:
2.1.2.1
]
Organism
ngi
Nannospalax galili (Upper Galilee mountains blind mole rat)
Pathway
ngi00260
Glycine, serine and threonine metabolism
ngi00630
Glyoxylate and dicarboxylate metabolism
ngi00670
One carbon pool by folate
ngi01100
Metabolic pathways
ngi01200
Carbon metabolism
ngi01230
Biosynthesis of amino acids
ngi01240
Biosynthesis of cofactors
ngi01523
Antifolate resistance
ngi04981
Folate transport and metabolism
Module
ngi_M00141
C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:
ngi00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00630 Glyoxylate and dicarboxylate metabolism
103724826 (Shmt1)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
103724826 (Shmt1)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
103724826 (Shmt1)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
103724826 (Shmt1)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
103724826 (Shmt1)
Enzymes [BR:
ngi01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.1 glycine hydroxymethyltransferase
103724826 (Shmt1)
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Ortholog
Paralog
GFIT
Motif
Pfam:
SHMT
Aminotran_1_2
Motif
Other DBs
NCBI-GeneID:
103724826
NCBI-ProteinID:
XP_008820173
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All DBs
Position
Un
AA seq
484 aa
AA seq
DB search
MAVPVNGAHRDAALWSSHDKMLAQSLKDSDIEVYSIIKKESNRQRVGLELIASENFASRA
VLEALGSCLNNKYSEGYPGHRYYGGTEFIDELETLCQKRALQAYHLDPQCWGVNVQPYSG
SPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVYPETGY
INYDQLEENARLFHPKLIVAGTSCYSRNLDYARLRKIADENRAYLMADMAHISGLVAAGV
VPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGVRSVDPKTGKEILYDLESLINSAVFPGL
QGGPHNHAIAGVAVALKQAMTTEFKVYQLQVIANCRALSEALTELGYKIVTGGSDNHLIL
VDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQK
VADFIHRGIELTLQIQNDMDARATLKEFKEKLAGDEKYQSAVQALREEVESFASNFSLPG
LQDF
NT seq
1455 nt
NT seq
+upstream
nt +downstream
nt
atggcggttcctgtcaatggagcccacagggatgctgccctctggtcttctcatgataag
atgttggctcagtccctcaaggacagtgacattgaggtttatagcattatcaaaaaggaa
agtaaccggcaaagggttggattggagctgattgcctcagagaattttgccagccgagca
gtattggaggccctgggatcttgcttaaataacaaatactcagaggggtacccaggccac
aggtattacggtgggaccgagttcattgatgagctggagacactgtgtcagaagcgagca
ctgcaggcctatcatctggaccctcagtgctggggggtcaatgtccagccttattcaggc
tcccctgcaaactttgctgtgtacactgccctcgtggagccccatgggcgtatcatgggt
ctggacctgccagatggaggccatcttactcatggcttcatgacagacaagaagaaaatc
tctgcgacatctattttcttcgaatctatgccctataaggtatacccagaaactggctac
atcaactatgaccagctggaggagaatgcccgcctctttcacccaaagctgatcgttgca
ggtaccagctgctactctcgaaacctagactatgcacgtttgcggaagattgctgatgaa
aaccgggcatatctcatggcagacatggcacacatcagtgggctggtggcagctggtgtg
gtgccatccccttttgaacactgccatgtagtgaccaccacaacccacaaaacgctgaga
ggctgccgtgctggtatgatattctacagaaaaggtgtgcggagtgtggatcccaagact
ggaaaagagattctgtatgacctggaatctctcatcaactctgctgtgttcccaggcctc
caagggggtccccacaatcatgccattgctggtgttgctgtggctctgaagcaggccatg
actacagaattcaaagtctaccagctccaggtgatagccaattgcagggctctgtctgag
gctctcacagagctaggctacaaaatagtcacaggtggttctgacaaccatttgatccta
gtggatctccgttctaagggcacagatgggggaagggctgagaaggtgttagaagcctgt
tctattgcctgcaacaagaatacctgcccaggtgaccggagtgcactacggcccagtgga
cttcgactggggactccagcactgacatcccgtggacttttggaaaaagatttccaaaaa
gtagcagactttatccacagagggatagaactgactctgcagattcagaatgacatggat
gcaagagccacgctcaaagagttcaaggagaaactggcaggggatgagaagtaccagagt
gctgtacaggctctccgggaggaagtggagagttttgcttccaacttctcacttcctggt
ctgcaggacttctga
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