KEGG   Nannospalax galili (Upper Galilee mountains blind mole rat): 103725801
Entry
103725801         CDS       T03372                                 
Symbol
Mre11, Mre11a
Name
(RefSeq) MRE11 homolog, double strand break repair nuclease
  KO
K10865  double-strand break repair protein MRE11
Organism
ngi  Nannospalax galili (Upper Galilee mountains blind mole rat)
Pathway
ngi03440  Homologous recombination
ngi03450  Non-homologous end-joining
ngi04218  Cellular senescence
Brite
KEGG Orthology (KO) [BR:ngi00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03440 Homologous recombination
    103725801 (Mre11)
   03450 Non-homologous end-joining
    103725801 (Mre11)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    103725801 (Mre11)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:ngi03032]
    103725801 (Mre11)
   03400 DNA repair and recombination proteins [BR:ngi03400]
    103725801 (Mre11)
DNA replication proteins [BR:ngi03032]
 Eukaryotic type
  DNA Replication Termination Factors
   MRN complex
    103725801 (Mre11)
DNA repair and recombination proteins [BR:ngi03400]
 Eukaryotic type
  DSBR (double strand breaks repair)
   HR (homologous recombination)
    MRN(MRX) complex
     103725801 (Mre11)
    BRCA1-C complex
     103725801 (Mre11)
   NHEJ (non-homologous end-joining)
    MRX complex
     103725801 (Mre11)
SSDB
Motif
Pfam: Mre11_DNA_bind Metallophos
Other DBs
NCBI-GeneID: 103725801
NCBI-ProteinID: XP_008821342
LinkDB
Position
Un
AA seq 706 aa
MSPADPLDDEDTFKILVATDIHLGYLEKDAVRGNDTFVTLDEILRLAQENEVDFILLGGD
LFHENKPSRKTLHTCLELLRKYCMGDRPVQFEIISDQSVNFGFSKFPWVNYQDGNLNISI
PVFSIHGNHDDPTGADALCALDILSCAGFVNHFGRSLSVEKIDISPILLQKGSTKMALYG
LGSIPDERLYRMFVNKKVTMLRPKEDESSWFNLFVIHQNRSKHGSTNFIPEQFLDDFIDL
VIWGHEHECKIGPTKNEQQLFYVSQPGSSVVTSLSPGEAVKKHVGLLRVKGRKMHMQKLP
LHTVRPFFMEDVVLANHPNLFNPDNPKVTQAIQSFCLEKIEEMLEGAERDRLGNSQQPEK
PLVRLRVDYSGGFEPFNSLRFSQKFVDRVANPKDIIHFFRQKQQKEKTEEINFGKLVTKP
SEGMTLRVEDLVKQYFQTAEKNVQLSLLTERGMGEAVQEFVDKEEKDAIEELVKYQLEKT
QRFLKERHIDALEDKIDEEVRRFRESRQRNADEEDDEVREAMNRARALRSQSENSASAFS
SDDLTSLDVAEQTANDSDDSLSAVPSRGRGRGRGRRGGRGQSAAPRGASQRGRGGTRLET
STQSRSSKATASTSRNMSILDAFRSTRQVPSRNIATKNYSEAIEVDESDEDDIFSASSKA
DQRWSGPSSSKRMSQSQIAQGVDFESDEDDDDDPFMSISSLRRSRR
NT seq 2121 nt   +upstreamnt  +downstreamnt
atgagccctgcagatccacttgacgatgaagacacatttaaaatcctggtcgccaccgat
attcatcttggatatttggagaaagatgcagttcgcggaaatgacacatttgttacactg
gatgaaattttaagacttgcccaggaaaatgaagtggattttattttgttaggtggtgat
cttttccatgaaaataagccctcgaggaaaaccctgcacacctgccttgaattactcagg
aagtactgcatgggagatcgccctgtgcaatttgaaattatcagtgaccagtctgtcaac
tttggttttagtaagtttccatgggtgaattaccaggacgggaatctcaacatttccatc
ccagtcttcagtatccacggcaatcacgacgatcccacgggggcagatgcgctctgtgcc
ctggacattttaagctgtgcgggatttgtgaaccactttggccggtcactgtctgtggag
aagatcgacatcagcccaattctgcttcagaaaggaagcacaaaaatggctctgtacggc
ttgggatccatcccagatgaacggctctatcggatgtttgtcaataaaaaggttaccatg
ttgagaccgaaggaggatgagagctcctggtttaatttgtttgtgattcatcagaacagg
agtaagcacggaagtactaacttcattccagaacagtttctggacgacttcatcgacctc
gttatctggggccatgaacatgagtgtaaaataggtccgaccaaaaacgagcagcagctc
ttttatgtctctcagcctggaagctcagtggtcacttctctctccccgggagaggctgtg
aagaaacacgtgggcttgctgcgcgtcaaagggcggaagatgcacatgcagaagctcccc
ctccatacagtacggccattcttcatggaggacgtggttctggccaaccacccgaacctg
ttcaaccctgacaaccctaaggtgacccaggccatccagagcttctgtttggagaagatt
gaagaaatgctggagggcgcagagcgggaccggctagggaattcccagcagccagagaag
cctctcgtacgactgcgggtggactacagtggggggtttgagcctttcaactctctgcgc
ttcagccagaagtttgtagatcgggttgctaacccgaaagacatcatccacttcttcagg
caaaaacagcagaaggaaaaaacagaagagatcaactttgggaagcttgtcacaaagcct
tcagaaggaatgaccctcagggtggaagacctggtgaagcagtatttccagactgcagag
aagaatgttcagctctccctgctcacagaaagagggatgggagaagccgtccaagaattt
gtggacaaggaggagaaggacgccattgaggagttggtgaagtaccagctggagaagacg
cagcggtttcttaaggagcgacatatcgacgccctggaagataaaatcgatgaagaggtc
cgtcgtttcagagaaagcagacagagaaatgccgacgaagaggacgatgaagttcgagag
gccatgaacagggcccgggccctcagatcccagtcggagaactcagcttccgccttcagc
agtgatgacctcacgagtctagatgtagcagaacagacagcaaatgactctgacgacagc
ctgtcagcagtgcccagcagaggacgaggccgcggccgaggccggagaggaggcagaggg
cagagtgccgcaccgagaggcgcatctcagaggggccgaggaggcaccaggctggagact
tctactcagagcaggagctcgaaggccactgcgtcaacctctcgaaatatgtccatttta
gatgccttcagatctacccgacaggtcccatctagaaacattgctactaagaactactca
gaggcaatcgaggtggatgagtctgatgaagatgacattttttctgccagttccaaggct
gaccaaaggtggtcaggcccatcgtccagcaaacgaatgtctcagagccagatagcccaa
ggggttgattttgagtcagatgaggatgatgatgatgaccctttcatgagcattagttct
ctaaggagaagccgaagataa

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