Nannospalax galili (Upper Galilee mountains blind mole rat): 103727040
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Entry
103727040 CDS
T03372
Symbol
Hspa5
Name
(RefSeq) heat shock protein family A (Hsp70) member 5
KO
K09490
endoplasmic reticulum chaperone BiP [EC:
3.6.4.10
]
Organism
ngi
Nannospalax galili (Upper Galilee mountains blind mole rat)
Pathway
ngi03060
Protein export
ngi04141
Protein processing in endoplasmic reticulum
ngi04612
Antigen processing and presentation
ngi04918
Thyroid hormone synthesis
ngi05012
Parkinson disease
ngi05014
Amyotrophic lateral sclerosis
ngi05020
Prion disease
ngi05022
Pathways of neurodegeneration - multiple diseases
ngi05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
ngi00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
03060 Protein export
103727040 (Hspa5)
04141 Protein processing in endoplasmic reticulum
103727040 (Hspa5)
09150 Organismal Systems
09151 Immune system
04612 Antigen processing and presentation
103727040 (Hspa5)
09152 Endocrine system
04918 Thyroid hormone synthesis
103727040 (Hspa5)
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
103727040 (Hspa5)
05014 Amyotrophic lateral sclerosis
103727040 (Hspa5)
05020 Prion disease
103727040 (Hspa5)
05022 Pathways of neurodegeneration - multiple diseases
103727040 (Hspa5)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
103727040 (Hspa5)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03110 Chaperones and folding catalysts [BR:
ngi03110
]
103727040 (Hspa5)
04131 Membrane trafficking [BR:
ngi04131
]
103727040 (Hspa5)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
ngi04147
]
103727040 (Hspa5)
Enzymes [BR:
ngi01000
]
3. Hydrolases
3.6 Acting on acid anhydrides
3.6.4 Acting on acid anhydrides to facilitate cellular and subcellular movement
3.6.4.10 non-chaperonin molecular chaperone ATPase
103727040 (Hspa5)
Chaperones and folding catalysts [BR:
ngi03110
]
Heat shock proteins
HSP70 / DNAK
103727040 (Hspa5)
Membrane trafficking [BR:
ngi04131
]
Endoplasmic reticulum (ER) - Golgi transport
Forward pathways
ER-Golgi intermediate compartment (ERGIC) proteins
103727040 (Hspa5)
Autophagy
ER-phagy
ER stress-related proteins
103727040 (Hspa5)
Exosome [BR:
ngi04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
103727040 (Hspa5)
Exosomal proteins of other body fluids (saliva and urine)
103727040 (Hspa5)
Exosomal proteins of colorectal cancer cells
103727040 (Hspa5)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
HSP70
MreB_Mbl
Hydantoinase_A
FtsA
DDR
FGGY_C
ParM_N
Motif
Other DBs
NCBI-GeneID:
103727040
NCBI-ProteinID:
XP_008823042
LinkDB
All DBs
Position
Un
AA seq
655 aa
AA seq
DB search
MKLSVVVVAALVLLCAVRAEEEDKKEDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGN
RITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKV
VEKKTKPYIQVDIGGGQTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDA
QRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDN
GVFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRAL
SSQHQARIEIESFYEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEI
VLVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDV
CPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLL
GTFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIE
RMVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSEDKETMEKAVE
EKIEWLESHQDADIEDFKAKKKELEEIVQPIISKLYGSAGPPPTGEEDTSEKDEL
NT seq
1968 nt
NT seq
+upstream
nt +downstream
nt
atgaagctctccgtggtggtggtggcggcgcttgtgctgctctgcgcagtgcgggctgag
gaggaggacaagaaggaggatgtgggcacggtggtcggcatcgatctggggaccacgtat
tcctgcgtcggggtgttcaagaacggccgcgtggagatcattgccaacgaccagggcaac
cgcatcacgccatcgtacgtggccttcacccctgaaggggagcgtctgattggcgatgcc
gccaagaaccagctcacgtccaaccccgagaacacggtcttcgacgccaagcgcctcata
ggacgcacttggaatgacccgtcagtgcagcaggacatcaagtttttgcctttcaaggtg
gttgagaagaaaaccaaaccatacattcaagtcgatattggaggtgggcaaaccaagaca
tttgctcccgaagaaatttctgccatggttctcactaaaatgaaagaaactgctgaggct
tatttgggaaagaaggttacccatgcagttgttactgtaccagcatatttcaatgatgcc
caaaggcaagcaaccaaagatgctggcactattgctggactgaatgtcatgaggatcatc
aacgagcctacagcagctgctattgcttatggcctggataagagggagggggagaagaac
atcctggtgtttgacctgggtggtggaaccttcgatgtgtctctcctcaccattgacaac
ggtgtctttgaagtcgtggcaactaatggagatactcatctgggtggagaagactttgat
cagcgtgttatggaacacttcatcaagctgtacaaaaagaagaccggcaaagatgtcaga
aaagacaatagagctgtgcagaagctccgccgtgaggtggaaaaggctaaacgggccctg
tcttctcagcatcaggcaaggattgaaattgagtctttctatgaaggagaagacttttct
gagacgctgactcgggccaaatttgaagagctaaacatggacctgttccgttctactatg
aagcctgtccagaaagtgttggaagattctgatttgaagaaatctgatattgatgaaatt
gttcttgttggtggttccactcgaattccaaagattcagcaactggtgaaagagttcttc
aatggcaaggagccatcccgtggcataaacccagatgaggctgtggcatatggtgctgct
gtccaggctggtgtactctctggtgatcaagatacaggtgatctggttctgcttgatgtg
tgtccccttacacttggtattgaaactgtgggaggtgtcatgaccaaactgattccaagg
aacactgtggtacctaccaagaagtctcagatcttttctacagcttctgataatcagcca
actgttacaatcaaggtctatgaaggtgaacgacccttgacaaaagacaatcatcttctg
ggtacatttgatctgactggaattcctcctgctcctcgtggagtgccccaaatagaagtc
acctttgagatagatgtgaatggcattctgcgagtgacagctgaggacaagggtacagga
aacaaaaataagatcacaattacaaatgaccaaaatcgcctgacacctgaagagattgaa
aggatggttaatgatgctgagaaatttgctgaggaagacaaaaagctgaaggagcgcatt
gataccaggaatgagttggaaagctatgcctactctctcaagaatcagattggggataaa
gaaaagctgggaggtaaactttcctctgaagataaagagaccatggaaaaagctgtagag
gaaaagattgaatggctggaaagccatcaggatgctgacattgaagactttaaagctaaa
aagaaggagctagaagaaattgttcaaccaattatcagcaaactctatggaagtgcaggc
cctcccccaactggtgaagaggatacatcagaaaaagatgagttgtag
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