Nannospalax galili (Upper Galilee mountains blind mole rat): 103727317
Help
Entry
103727317 CDS
T03372
Symbol
Fpgs
Name
(RefSeq) folylpolyglutamate synthase
KO
K01930
folylpolyglutamate synthase [EC:
6.3.2.17
]
Organism
ngi
Nannospalax galili (Upper Galilee mountains blind mole rat)
Pathway
ngi00790
Folate biosynthesis
ngi01100
Metabolic pathways
ngi01240
Biosynthesis of cofactors
ngi01523
Antifolate resistance
ngi04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
ngi00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
103727317 (Fpgs)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
103727317 (Fpgs)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
103727317 (Fpgs)
Enzymes [BR:
ngi01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.17 tetrahydrofolate synthase
103727317 (Fpgs)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Mur_ligase_C
Motif
Other DBs
NCBI-GeneID:
103727317
NCBI-ProteinID:
XP_008823382
LinkDB
All DBs
Position
Un
AA seq
487 aa
AA seq
DB search
MCLWKKSDWGRKGPGAREGSPDDPRSPGSSPHLVQVRERIRINGQPISPELFTKHFWRLY
HRLEETKDGSHAPMPAYFRFLTLMAFHIFLQEKVDLAVVEVGIGGAYDCTNIIRKPVVCG
VSSLGIDHTSLLGDTMEKIAWQKGGIFKPGVPAFTVPQPDGPLAVLRDRAQQISCPLYLC
PPLEALEEEGRPLMLGLEGEHQRSNAALALQLAHCWLQWQDHHDIWELKVSSPNTWWQLP
LAPRFQPTSRMQHGLRDTEWPGRTQVLRRGPLTWYLDGAHTTSSVQACVRWFHQSLQRNE
RPSGGPEVHVLLFNSTGDRDPAALLKLLQPCQFDYAVFCPNLTEVSATSNADQQNFTVTL
DQVLLRCLQHQQHWSCLSEKQASPDLWNTPSTEPDGPASLLLAPHPPHPTNTSSLVFSCI
SHALQWISQGRDPIFQPPSPPKGLFSHPTASSGASVLREAAAIHVLVTGSLHLVGGVLRL
LEPSLSQ
NT seq
1464 nt
NT seq
+upstream
nt +downstream
nt
atgtgtttatggaagaagtctgactggggcaggaaaggccctggggctcgggaaggaagt
cccgatgaccccagatctcccggcagctctcctcacctggtgcaggtgcgtgagcggatc
cgaatcaatgggcagcccatcagccctgagctcttcaccaagcacttctggcgcctctac
caccggctggaggagaccaaggatggcagccacgcccccatgcccgcctacttccgcttc
ctcacactcatggccttccacatcttcctccaagagaaggtggacctggccgtggtagaa
gtgggcatcggtggggcttacgactgtaccaacatcattaggaagcctgtggtatgtgga
gtgtcctctcttggcattgaccacaccagcctgctaggagacaccatggagaagatagca
tggcagaaagggggcatctttaagcctggtgtccctgccttcactgtgccacagccagac
ggtcccctggccgtgctgagggatcgagcccagcagatctcatgtcctctctacctgtgt
cccccgctggaagccctggaggaggagggaaggccattgatgctgggcctggagggagaa
caccagcggtccaatgcagccttggccttgcagctggctcattgctggttacagtggcag
gaccaccatgatatctgggagctgaaggtgtctagcccaaacacatggtggcaactgccc
ctggcaccaaggttccaacccacatcccgtatgcaacatgggcttcgggacacggagtgg
cctggccggacacaggtgctgcggaggggaccccttacctggtacctggatggggcacac
accaccagcagcgtgcaggcctgtgttcgctggttccatcagtcgctgcagcgtaatgag
cgacccagtggtggacctgaggtacatgtcttgctcttcaactctactggagacagggac
ccagcagccctgctgaagttgctgcagccctgtcagtttgactatgctgtcttctgtccc
aacctgacagaggtgtcggccacaagtaatgcagaccagcagaacttcacagtgactctg
gaccaagtgctgctccgctgcctccaacaccagcagcactggagctgcctgagtgaaaag
caggccagcccggacctctggaacacccccagcacggaacctgacgggccagcctccctg
cttctggctccccaccctccccatcccaccaacaccagctcccttgtgttcagctgcatt
tcccacgccttgcagtggatcagccaaggccgggaccctatctttcagcccccaagtcct
ccaaagggcctgttcagccaccccactgccagcagtggggccagcgttctccgggaggct
gctgccatccatgtactggtcacaggaagcctgcatctggtgggtggagtcctgaggctg
ttggagccctccctgtcccagtag
DBGET
integrated database retrieval system
