Nannospalax galili (Upper Galilee mountains blind mole rat): 103727692
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Entry
103727692 CDS
T03372
Symbol
Atic
Name
(RefSeq) 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
KO
K00602
phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:
2.1.2.3
3.5.4.10
]
Organism
ngi
Nannospalax galili (Upper Galilee mountains blind mole rat)
Pathway
ngi00230
Purine metabolism
ngi00670
One carbon pool by folate
ngi01100
Metabolic pathways
ngi01523
Antifolate resistance
Module
ngi_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
ngi00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
103727692 (Atic)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
103727692 (Atic)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
103727692 (Atic)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
ngi04147
]
103727692 (Atic)
Enzymes [BR:
ngi01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase
103727692 (Atic)
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.10 IMP cyclohydrolase
103727692 (Atic)
Exosome [BR:
ngi04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
103727692 (Atic)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
AICARFT_IMPCHas
MGS
Ribosomal_L12_N
DUF5938
Motif
Other DBs
NCBI-GeneID:
103727692
NCBI-ProteinID:
XP_008823898
UniProt:
A0A8C6RKS3
LinkDB
All DBs
Position
Un
AA seq
592 aa
AA seq
DB search
MAPGQLALFSVSDKTGLVEFARSLASLGLSLVASGGTAKALRDAGLAVRDVSELTGFPEM
LGGRVKTLHPAVHAGILARSIPEDNADMARLDFSLIRVVACNLYPFVNTVASPDVTVEAA
VEQIDIGGVTLLRAAAKNHARVTVVCEPEDYVAVSTEMQSSDSKDTSLETRRHLALKAFT
HTAQYDEAISDYFRKQYSKGISQMPLRYGMNPHQTPAQLYTLKPKLPITVLNGAPGFINL
CDALNAWQLVKELKEALDIPAAASFKHVSPAGAAVGIPVSEDEAKVCMVYDLYPTLTPVS
TAYARARGADRMSSFGDFIALSDICDIPTAKIISREVSDGIVAPGYEEEALKILSKKKNG
NYCVLQMDPSYKPDENEVRTLFGLRLSQKRNNGVIDKSLFSNVVTKNKDLPESALRDLIV
ATIAVKYTQSNSVCYAKDGQVIGIGAGQQSRIHCTRLAGDKANCWWLRHHPRVLSMKFKA
GVKRAEISNAIDQYVTGTIGEGEDLVKWKALFEEVPELLTKVEKEEWVNKLSEVSVSSDA
FFPFRDNVDRAKRSGVAYIAAPSGSAADKVVIEACDELGIILAHTDLRLFHH
NT seq
1779 nt
NT seq
+upstream
nt +downstream
nt
atggcccccggccagctcgccctgttcagtgtgtctgacaaaactggcctcgtggaattt
gccagaagcctcgcatctcttggtctgagtctagtcgcttccggaggcactgcaaaagct
ctccgggacgctggcctggcagtcagagatgtgtctgagcttacggggtttcctgaaatg
ttaggggggcgtgtgaaaaccttgcatcctgcagtccacgctggaatcttggcacgcagt
attccagaagataatgctgacatggccagacttgatttcagccttataagagtcgttgcc
tgtaacctgtatccttttgtgaacaccgtggcttctccggatgtaactgttgaggcagct
gttgagcaaatcgacattggtggagtgaccttgctgagagctgcagccaaaaaccacgct
cgagtcacagttgtgtgcgaaccagaggactacgtggccgtgtccacagagatgcagagc
tctgacagcaaggacacctccttggagaccaggcgtcacttagccttgaaggcatttact
catactgcacaatatgatgaagcaatttcagattacttcaggaaacagtacagtaaagga
atctctcagatgcccttgaggtatggaatgaaccctcatcagactcctgcccagctgtac
acgctgaagcccaaactccccatcacagttctcaatggagccccaggattcataaacctg
tgtgatgccttgaatgcctggcagctggtgaaggaactcaaagaagctttagacattcca
gctgcagcttctttcaagcacgtcagcccagcaggtgctgctgttggaattccagtcagt
gaagatgaggccaaagtctgcatggtctatgacctctacccgaccctcacacctgtatct
actgcgtatgccagagcaagaggggccgataggatgtcttcatttggtgattttattgca
ttatctgacatctgtgatatcccgactgcaaaaatcatctccagagaagtgtcagatggt
attgttgctccgggatacgaagaagaagccttgaaaatactttctaaaaagaaaaatgga
aactactgtgttcttcagatggacccatcttacaaaccagatgaaaatgaagttcgaaca
ctctttggtcttcgtttaagccagaagagaaacaatggtgtcatcgacaaatcattgttt
agcaatgttgttaccaagaataaagatctgccggagtctgcccttagagacctcatcgtg
gccaccattgctgtcaagtatactcagtctaactccgtgtgctatgccaaggacgggcag
gtcattggcatcggagcaggtcagcagtctcggatccactgtacacgccttgcaggagat
aaggcaaactgctggtggcttagacaccacccacgagtactttctatgaagttcaaagct
ggagtgaagagagcagaaatctccaatgccattgatcagtatgtaactggcaccattggt
gagggtgaagacttggtgaagtggaaggcactgtttgaggaagtccctgagttactcacc
aaggtggagaaggaggagtgggtcaacaaactgagtgaggtttccgtcagctccgacgcc
ttctttcctttccgggataacgtagacagagctaaaaggagtggcgtggcctacattgca
gctccttctggttctgctgctgacaaggttgtgattgaggcttgtgatgaactggggatc
atcttggctcacacagatcttcggctcttccaccactga
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