Nannospalax galili (Upper Galilee mountains blind mole rat): 103728037
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Entry
103728037 CDS
T03372
Symbol
Ppp3ca
Name
(RefSeq) protein phosphatase 3 catalytic subunit alpha
KO
K04348
serine/threonine-protein phosphatase 2B catalytic subunit [EC:
3.1.3.16
]
Organism
ngi
Nannospalax galili (Upper Galilee mountains blind mole rat)
Pathway
ngi04010
MAPK signaling pathway
ngi04020
Calcium signaling pathway
ngi04022
cGMP-PKG signaling pathway
ngi04114
Oocyte meiosis
ngi04218
Cellular senescence
ngi04310
Wnt signaling pathway
ngi04360
Axon guidance
ngi04370
VEGF signaling pathway
ngi04380
Osteoclast differentiation
ngi04625
C-type lectin receptor signaling pathway
ngi04650
Natural killer cell mediated cytotoxicity
ngi04658
Th1 and Th2 cell differentiation
ngi04659
Th17 cell differentiation
ngi04660
T cell receptor signaling pathway
ngi04662
B cell receptor signaling pathway
ngi04720
Long-term potentiation
ngi04724
Glutamatergic synapse
ngi04728
Dopaminergic synapse
ngi04921
Oxytocin signaling pathway
ngi04922
Glucagon signaling pathway
ngi04924
Renin secretion
ngi05010
Alzheimer disease
ngi05014
Amyotrophic lateral sclerosis
ngi05020
Prion disease
ngi05022
Pathways of neurodegeneration - multiple diseases
ngi05031
Amphetamine addiction
ngi05152
Tuberculosis
ngi05163
Human cytomegalovirus infection
ngi05166
Human T-cell leukemia virus 1 infection
ngi05167
Kaposi sarcoma-associated herpesvirus infection
ngi05170
Human immunodeficiency virus 1 infection
ngi05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
ngi05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
ngi00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
103728037 (Ppp3ca)
04310 Wnt signaling pathway
103728037 (Ppp3ca)
04370 VEGF signaling pathway
103728037 (Ppp3ca)
04020 Calcium signaling pathway
103728037 (Ppp3ca)
04022 cGMP-PKG signaling pathway
103728037 (Ppp3ca)
09140 Cellular Processes
09143 Cell growth and death
04114 Oocyte meiosis
103728037 (Ppp3ca)
04218 Cellular senescence
103728037 (Ppp3ca)
09150 Organismal Systems
09151 Immune system
04625 C-type lectin receptor signaling pathway
103728037 (Ppp3ca)
04650 Natural killer cell mediated cytotoxicity
103728037 (Ppp3ca)
04660 T cell receptor signaling pathway
103728037 (Ppp3ca)
04658 Th1 and Th2 cell differentiation
103728037 (Ppp3ca)
04659 Th17 cell differentiation
103728037 (Ppp3ca)
04662 B cell receptor signaling pathway
103728037 (Ppp3ca)
09152 Endocrine system
04922 Glucagon signaling pathway
103728037 (Ppp3ca)
04921 Oxytocin signaling pathway
103728037 (Ppp3ca)
04924 Renin secretion
103728037 (Ppp3ca)
09156 Nervous system
04724 Glutamatergic synapse
103728037 (Ppp3ca)
04728 Dopaminergic synapse
103728037 (Ppp3ca)
04720 Long-term potentiation
103728037 (Ppp3ca)
09158 Development and regeneration
04360 Axon guidance
103728037 (Ppp3ca)
04380 Osteoclast differentiation
103728037 (Ppp3ca)
09160 Human Diseases
09161 Cancer: overview
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
103728037 (Ppp3ca)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
103728037 (Ppp3ca)
05170 Human immunodeficiency virus 1 infection
103728037 (Ppp3ca)
05163 Human cytomegalovirus infection
103728037 (Ppp3ca)
05167 Kaposi sarcoma-associated herpesvirus infection
103728037 (Ppp3ca)
09171 Infectious disease: bacterial
05152 Tuberculosis
103728037 (Ppp3ca)
09164 Neurodegenerative disease
05010 Alzheimer disease
103728037 (Ppp3ca)
05014 Amyotrophic lateral sclerosis
103728037 (Ppp3ca)
05020 Prion disease
103728037 (Ppp3ca)
05022 Pathways of neurodegeneration - multiple diseases
103728037 (Ppp3ca)
09165 Substance dependence
05031 Amphetamine addiction
103728037 (Ppp3ca)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
103728037 (Ppp3ca)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
ngi01009
]
103728037 (Ppp3ca)
Enzymes [BR:
ngi01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.16 protein-serine/threonine phosphatase
103728037 (Ppp3ca)
Protein phosphatases and associated proteins [BR:
ngi01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Calcineurin (PPP3/ PP2B)
Catalytic subunits
103728037 (Ppp3ca)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Metallophos
Motif
Other DBs
NCBI-GeneID:
103728037
NCBI-ProteinID:
XP_017651875
UniProt:
A0A8C6RNG5
LinkDB
All DBs
Position
Un
AA seq
521 aa
AA seq
DB search
MSEPKAIDPKLSTTDRVVKAVPFPPSHRLTAKEVFDNDGKPRVDILKAHLMKEGRLEESV
ALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYV
DRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMD
AFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFG
NEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFP
SLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEK
VTEMLVNVLNICSDDELGSEEDGFDGATAAARKEVIRNKIRAIGKMARVFSVLREESESV
LTLKGLTPTGMLPSGVLSGGKQTLQSATVEAIEADEAIKGFSPQHKITSFEEAKGLDRIN
ERMPPRRDALPSDANLNSINKALASETNGTDSNGSNSSNIQ
NT seq
1566 nt
NT seq
+upstream
nt +downstream
nt
atgtccgagcccaaggcaattgatcccaagttgtcgacgaccgacagggtggtgaaagct
gttccatttcctccaagtcaccgacttacagcaaaggaagtgtttgataatgatggaaaa
cctcgtgtggatatcttaaaagcacatctcatgaaggagggcaggctggaagagagtgtt
gctttgagaataataacagagggtgcttcaattcttcgacaggaaaaaaacttgctggat
atcgatgcaccagtcacagtttgtggggacatccatggacaattttttgacttaatgaag
ctctttgaagtcgggggctctcctgccaacactcgctacctcttcttaggggactatgtg
gacagagggtacttcagtatcgagtgtgtgctgtatttgtgggccttgaaaattctttac
cccaaaacactgtttttacttcgtggaaatcatgaatgtagacatctaacagagtatttc
acatttaaacaagaatgtaaaataaagtattcagaacgtgtatatgacgcctgtatggac
gccttcgactgccttcccctggcggcgctgatgaaccaacagttcctgtgtgtacatggt
ggtttgtctccagagattaacactctagatgacatcagaaaattagaccgattcaaagaa
ccacctgcttatggacccatgtgtgacatcctgtggtcagaccccctggaggactttgga
aatgagaagactcaggagcatttcactcacaacacagtcagggggtgttcctacttctac
agttacccggctgtatgtgaattcttgcagcacaataacttgttatctatactccgagcc
catgaagcccaagatgcagggtaccgcatgtacaggaaaagccaaacaacaggcttcccc
tctctaattacaattttctcagcaccaaattacttagatgtgtacaataacaaagctgca
gtattgaaatatgagaacaatgttatgaatatcaggcagttcaactgttccccccatcca
tactggctcccaaatttcatggatgttttcacctggtcactgccatttgttggagagaaa
gtgactgagatgctggtaaatgtccttaacatctgctcagatgatgaactggggtccgaa
gaagatggatttgatggagccactgctgcagcacggaaggaagtgatacggaacaagatc
cgagcaataggaaaaatggccagagtgttctcggttctcagagaagagagtgagagtgtt
ctgacgctgaaaggcttgaccccaaccggcatgctccccagcggagtgctttctggaggg
aaacaaaccctgcaaagcgctactgttgaggctattgaggctgatgaagctatcaaagga
ttttcaccacagcataagatcactagcttcgaggaggccaagggcttagaccgaattaac
gagcggatgccgccccgcagagacgccctgccctctgacgccaaccttaactccatcaac
aaggctctcgcctcagagactaacggcacggacagcaatggcagtaacagcagcaatatc
cagtga
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