Nannospalax galili (Upper Galilee mountains blind mole rat): 103732657
Help
Entry
103732657 CDS
T03372
Symbol
Acaca
Name
(RefSeq) acetyl-CoA carboxylase alpha
KO
K11262
acetyl-CoA carboxylase / biotin carboxylase 1 [EC:
6.4.1.2
6.3.4.14
2.1.3.15
]
Organism
ngi
Nannospalax galili (Upper Galilee mountains blind mole rat)
Pathway
ngi00061
Fatty acid biosynthesis
ngi00620
Pyruvate metabolism
ngi00640
Propanoate metabolism
ngi01100
Metabolic pathways
ngi01212
Fatty acid metabolism
ngi04152
AMPK signaling pathway
ngi04910
Insulin signaling pathway
ngi04922
Glucagon signaling pathway
ngi04936
Alcoholic liver disease
Module
ngi_M00082
Fatty acid biosynthesis, initiation
Brite
KEGG Orthology (KO) [BR:
ngi00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
103732657 (Acaca)
00640 Propanoate metabolism
103732657 (Acaca)
09103 Lipid metabolism
00061 Fatty acid biosynthesis
103732657 (Acaca)
09110 Biosynthesis of other secondary metabolites
00254 Aflatoxin biosynthesis
103732657 (Acaca)
09130 Environmental Information Processing
09132 Signal transduction
04152 AMPK signaling pathway
103732657 (Acaca)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
103732657 (Acaca)
04922 Glucagon signaling pathway
103732657 (Acaca)
09160 Human Diseases
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
103732657 (Acaca)
Enzymes [BR:
ngi01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.3 Carboxy- and carbamoyltransferases
2.1.3.15 acetyl-CoA carboxytransferase
103732657 (Acaca)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.4 Other carbon-nitrogen ligases
6.3.4.14 biotin carboxylase
103732657 (Acaca)
6.4 Forming carbon-carbon bonds
6.4.1 Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
6.4.1.2 acetyl-CoA carboxylase
103732657 (Acaca)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
ACC_central
Carboxyl_trans
CPSase_L_D2
ACCA_BT
Biotin_carb_N
Biotin_carb_C
Biotin_lipoyl
ATP-grasp
Dala_Dala_lig_C
ATP-grasp_3
Motif
Other DBs
NCBI-GeneID:
103732657
NCBI-ProteinID:
XP_008829526
UniProt:
A0A8C6RHF0
LinkDB
All DBs
Position
Un
AA seq
2346 aa
AA seq
DB search
MDEPSSLDQPLELNQHSRFIIGSVSEDNSEDEISNLVKLDLLEEKEGSLSPASVSSDTLS
DLGISGLQDGLAFHLRSSMSGLHLVKQGRDRKKIDSQRDFTVASPAEFVTRFGGNKVIEK
VLIANNGIAAVKCMRSIRRWSYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPG
GPNNNNYANVELILDIAKRIPVQAVWAGWGHASENPKLPELLLKNGIAFMGPPSQAMWAL
GDKIASSIVAQTAGIPTLPWSGSGLRVDWQENDFSKRILNVPQELYEKGYVKDVDDGLKA
AEEVGYPVMIKASEGGGGKGIRKVNNADDFPNLFRQVQAEVPGSPIFVMRLAKQSRHLEV
QILADQYGNAISLFGRDCSVQRRHQKIIEEAPAAIATPAVFEHMEQCAVKLAKMVGYVSA
GTVEYLYSQDGSFYFLELNPRLQVEHPCTEMVADVNLPAAQLQIAMGIPLFRIKDIRMMY
GVSPWGDIPIDFENSAHVPCPRGHVIAARITSENPDEGFKPSSGTVQELNFRSNKNVWGY
FSVAAAGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLIKLLET
ESFQLNRIDTGWLDRLIAEKVQAERPDTMLGVVCGALHVADVNLRNSISNFLHSLERGQV
LPAHTLLNTVDVELIYEGVKYVLKVTRQSPNSYVVIMNGSCVEVDVHRLSDGGLLLSYDG
SSYTTYMKEEVDRYRITIGNKTCVFEKENDPSVMRSPSAGKLIQYIVEDGGHVFAGQCYA
EIEVMKMVMTLTAVESGCIHYVKRPGAALDPGCVIAKMQLDNPSKVQQAELHTGSLPQIQ
STALRGEKLHRVFHYVLDNLVNVMNGYCLPDPFFSNRVKDWVERLMKTLRDPSLPLLELQ
DIMTSVSGRIPLNVEKSIKKEMAQYASNITSVLCQFPSQQIANILDSHAATLNRKSEREV
FFMNTQSIVQLVQRYRSGIRGHMKAVVMDLLRQYLRVETQFQNGHYDKCVFALREENKSD
MNTVLNYIFSHAQVTKKNLLVTMLIDQLCGRDPTLTDELLNILTELTQLSKTTNAKVALR
ARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQFCIENLQKLILSETSIFDVLPNFFYH
SNQVVRMAALEVYVRRAYIAYELNSVQHRQLKDNTCVVEFQFMLPTSHPNRGNIPTLNRM
SFASNLNHYGMTHVASVSDVLLDNSFTPPCQRMGGMVSFRTFEDFVRIFDEVMGCFCDSP
PQSPTFPESGHTSLYDEDKVPRDEPIHILNVAIKTDGDIEDDRLAAMFREFTQQNKATLV
EHGIRRLTFLVAQKDFRKQVNCEVDQRFHREFPKFFTFRARDKFEEDRIYRHLEPALAFQ
LELNRMRNFDLTAIPCANHKMHLYLGAAKVEVGTEVTDYRFFVRAIIRHSDLVTKEASFE
YLQNEGERLLLEAMDELEVAFNNTNVRTDCNHIFLNFVPTVIMDPSKIEESVRSMVMRYG
SRLWKLRVLQAELKINIRLTTTGKAIPIRLFLTNESGYYLDISLYKEVTDSRTAQIMFQA
YGDKQGPLHGMLINTPYVTKDLLQSKRFQAQSLGTTYIYDIPEMFRQSLIKLWESMSSQA
FLPSPPLPSDILTYTELVLDDQGQLVHMNRLPGGNEIGMVAWKMSLKSPEYPDGRDIIVI
GNDITYRIGSFGPQEDLLFLRASELARAEGIPRIYVAANSGARIGLAEEIRHMFHVAWVD
PEDPYKGYKYLYLTPQDYKRVSALNSVHCEHVEDEGESRYKITDIIGKEEGLGAENLRGS
GMIAGESSLAYDEIITISLVTCRAIGIGAYLVRLGQRTIQVENSHLILTGAGALNKVLGR
EVYTSNNQLGGIQIMHNNGVTHCTVCDDFEGVFTVLHWLSYMPKSMHSSVPLLNSKDPID
RIIEFVPTKAPYDPRWMLAGRPHPTQKGQWLSGFFDYGSFSEIMQPWAQTVVVGRARLGG
IPVGVVAVETRTVELSIPADPANLDSEAKIIQQAGQVWFPDSAFKTYQAIKDFNREGLPL
MVFANWRGFSGGMKDMYDQVLKFGAYIVDGLRECSQPVMVYIPPQAELRGGSWVVIDPTI
NPRHMEMYADRESRGSVLEPEGTVEIKFRKKDLVKTMRRVDPVYIHLAERLGTPELSPAE
RKELENKLKEREEFLIPIYHQVAVQFADLHDTPGRMQEKGVINDILDWKTSRTFFYWRLR
RLLLEDLVKKKIHNANPELTDGQIQAMLRRWFVEVEGTVKAYVWDNNKDLVEWLEKQLTE
EDGVRSVIEENIKYISRDYILKQIRSLVQANPEVAMDSIVHMTQHISPTQRAEVVRILST
MDSPST
NT seq
7041 nt
NT seq
+upstream
nt +downstream
nt
atggatgaaccatcttcattggaccaacccctggagctgaaccagcactcccggttcata
attgggtctgtgtctgaagacaactcagaagatgagatcagcaacctggtgaagctggac
ctgctggaggagaaggagggctctctgtcaccagcttctgtcagctcagatacactttct
gatttggggatctctggtttacaggatggtttggcttttcacttgaggtccagcatgtct
ggcttgcacctagtaaaacaaggtcgagacagaaagaaaatagactcacagcgagatttc
actgttgcttctccagcagaatttgttactcgttttgggggaaataaagtgattgagaag
gttcttattgccaacaatggtattgcagcagtgaaatgtatgcgatctatccgtcggtgg
tcttatgaaatgtttcgaaatgagcgtgcaatccgatttgttgtcatggttacacctgaa
gaccttaaagccaatgcagaatacattaagatggcagatcactatgttccagtgcctgga
ggaccaaacaacaacaattatgcaaatgtggaattaattcttgatattgctaaaaggatc
cctgtacaagcagtatgggctggttggggtcatgcttctgaaaaccccaagcttccagag
ctactcttaaaaaatggcatcgccttcatgggccctccaagccaggctatgtgggcttta
ggggataagattgcatcttctatagtggctcaaactgcaggtatcccaactcttccctgg
agtggcagtggtcttcgtgtggattggcaagaaaatgatttttcgaaacgtatcttaaat
gttccacaggaactatatgagaaaggttatgtgaaggatgtggatgatggactgaaggca
gcagaggaagttggatatccagtaatgatcaaggcctcagaaggaggaggagggaaggga
atcagaaaagttaacaatgcagatgacttccctaacctctttagacaggttcaagcggaa
gtccctggatctcctatctttgtaatgagactagcaaaacaatctcgtcacctggaggtc
cagattctagcagatcagtatggcaatgccatttctttgtttggccgtgactgctctgta
cagcgcagacatcagaaaatcattgaagaggcacctgctgctattgctaccccagcagta
tttgaacatatggaacagtgtgcagtgaaacttgccaaaatggttggttatgtgagtgct
gggaccgtggaatacttgtacagccaggatggcagcttctactttctggaactgaaccct
cggctacaggttgaacacccttgtacagagatggtggctgatgtaaacctccctgcagca
cagctccagattgctatggggatccctctgttcaggatcaaggatatccgtatgatgtat
ggggtatctccttggggtgatattcccattgattttgaaaattctgcacatgttccttgc
ccaaggggccacgtaattgccgctcggatcactagtgaaaatccagatgaggggtttaag
cccagctcgggaacagttcaggaactaaattttcgcagcaataagaacgtttggggttat
ttcagtgttgctgctgctgggggacttcatgaatttgctgattctcagtttggtcactgc
ttttcctggggagaaaacagagaagaagcaatttcaaatatggtggtggcattgaaggag
ctatctattcggggtgattttcgaactacagttgaatacttgatcaaattgttagagact
gaaagctttcagttgaatagaattgatactggctggctggacagactgatagcagaaaaa
gtacaggcagaacgtcctgacactatgttgggagttgtgtgtggagcccttcatgtggca
gatgtgaacctgcggaatagcatctctaatttccttcactccttagaaaggggtcaagtc
cttcctgctcacacacttttgaacacagtagacgttgaacttatctatgaaggagtcaaa
tatgttcttaaggtgactcgacagtctcccaactcctatgtggtgatcatgaatggttca
tgtgtagaagtagatgtgcatcggctaagtgatggtggactgcttttgtcttatgatggc
agcagttataccacatacatgaaggaggaagtggatagataccgcatcacgattggcaat
aaaacctgtgtgtttgagaaggaaaacgacccgtctgtgatgcgctcaccttctgctggg
aagttaatccagtacatcgtggaggatggaggccatgtgtttgctggccagtgctatgct
gagattgaggtaatgaagatggtgatgaccttaacagctgtagaatctggctgcatccat
tatgtcaagcgacctggagcggctcttgaccctggctgtgtgatagccaaaatgcagctg
gacaacccaagcaaggttcagcaggctgagcttcatacaggtagtctgccacagatccag
agcacagctctcagaggcgagaagctccatcgagtgttccactatgtcctggataacctg
gtcaatgtgatgaatggatactgccttccagatcctttcttcagcaacagggtaaaagac
tgggtggaacgattgatgaaaactctcagagatccatccctgcctcttctagaattacag
gatattatgaccagtgtttctggccgtatccccctcaatgtagaaaagtctattaagaag
gaaatggctcaatatgccagcaacatcacatctgtcctctgtcagtttcccagccagcag
attgccaacatcctagatagtcatgcagctaccttgaaccggaaatctgaacgggaggtc
ttcttcatgaacactcagagcattgtccaactggtgcagaggtaccgaagtggcattcga
ggccacatgaaggctgtggtgatggatctgctccgacagtacctaagggtagagacgcag
ttccagaatggccactacgacaaatgtgtgtttgcccttcgggaggagaacaaaagtgac
atgaacactgtgctgaactacatcttctctcatgctcaagtcaccaaaaagaatctcctg
gtcacgatgcttattgatcagctgtgtggccgggacccgactctcactgatgagctatta
aatatcctcacagagctaactcaactcagtaagaccacaaatgctaaagtagcacttcgg
gctcgtcaggttcttattgcttcccatttgccatcgtatgagcttcgccataaccaagta
gagtctatcttcctatcagctattgacatgtatggacatcagttttgcattgagaacctg
cagaaattgatcctatcggaaacatctatttttgatgttctaccaaacttcttttatcac
agcaaccaagttgtaaggatggcagctctggaggtatatgttcgaagggcttatattgcc
tatgaacttaacagtgtacaacaccgccagctaaaagacaatacctgcgtggtggaattt
cagtttatgttgcccacatctcatccaaacagagggaacatccccacgctaaacagaatg
tccttcgcctccaacctcaaccactacggcatgactcatgtagctagtgtcagcgatgtg
ctgttggacaattccttcactccaccttgtcagcggatgggcggaatggtctcttttcgg
acttttgaagattttgtcaggatctttgatgaagtgatgggctgcttctgtgactcccca
ccccaaagccccacatttccagagtcaggtcatacatcactctatgatgaagacaaggtt
cccagggatgaaccgattcacattctgaatgtggctatcaagactgatggtgatattgag
gatgacaggctggcagctatgtttagagagtttacccagcaaaataaagctactttggtt
gagcatgggattcggcgtcttacgttcctggttgcacaaaaggatttcagaaaacaggtc
aactgtgaggtggatcagagatttcatagagaattccctaaatttttcacattccgggca
agggataagtttgaggaagatcgtatttaccgtcacctggagcctgctttggccttccag
ttagagctgaaccggatgagaaattttgacctcactgccattccatgtgctaatcacaag
atgcacctatatcttggggcagccaaggtagaagtgggcacagaagtgacagactacagg
ttctttgttcgtgcaatcatcaggcattctgatctggtcacaaaggaagcttcatttgaa
tatctacaaaatgaaggggagcggctactcctggaagccatggatgagttggaagttgct
tttaacaatacaaatgtccgcactgactgtaaccacatcttcctcaactttgtgcccaca
gtcatcatggacccttcaaagattgaagaatctgtgcggagcatggtaatgcgctatgga
agtcggctgtggaaattgcgcgtcctccaggcagaactgaaaatcaacattcgcctgaca
acaactggaaaagcaattcccatacgcctcttcctgacaaatgagtctggctattacttg
gacatcagcctatacaaagaagtgactgactccaggacagcacagatcatgtttcaagca
tatggagataagcagggaccactgcatggaatgttaatcaacactccatatgtgaccaaa
gacctccttcagtcaaagaggtttcaggcacagtccttgggaacaacatatatatatgat
atcccagagatgtttcgacagtccctcatcaaactctgggagtctatgtcctctcaagca
ttccttccctcaccgcctctgccttctgacattctgacgtatactgaactggtgttggac
gatcaaggccagctggtccacatgaacaggcttccaggaggaaatgagattggcatggta
gcttggaaaatgagccttaaaagtccagaatatccagatggccgagatataattgtcatt
ggcaatgacataacatatcggattgggtcctttgggcctcaggaagatttgctgtttctc
agagcttctgagcttgccagagctgagggtatcccacgcatctatgtagcagccaacagt
ggagcaagaattggactggctgaagaaattcgtcatatgttccatgtggcctgggtagat
cctgaggatccttacaagggatataagtatttgtacctgacaccccaggattataaaaga
gtcagtgctctcaactctgtccattgtgaacatgtggaggatgaaggagaatccaggtac
aaaataacagatattattgggaaagaagaaggacttggtgcagagaaccttcgaggttct
ggaatgattgctggagagtcttcattggcctatgatgaaatcatcaccatcagcctggtg
acgtgccgggccattgggattggagcctaccttgtccggctaggacaaagaaccatccag
gttgagaattctcacttaattctgacaggagctggtgccctcaacaaagtccttggccgg
gaagtatacacctccaacaatcagcttgggggcatccagatcatgcacaacaatggagtt
actcattgcacggtctgtgatgactttgaaggggttttcactgtcttgcactggctgtca
tatatgcctaagagcatgcatagttcagttcctctcctgaattccaaggatcctatagat
agaatcatcgagtttgttcccacaaaggccccatatgatcctcggtggatgctggcaggc
cgtcctcatccaacccaaaaaggccaatggttgagtggattttttgactatggatctttc
tcggagattatgcagccctgggcacagacagtggtggttggtagagccaggttaggagga
atacctgtgggagtagttgccgtagaaacccgaactgtagaactcagtatcccagctgat
cctgcaaacctggattctgaagccaagataatccagcaggctggtcaggtttggttccca
gactctgcatttaagacctatcaagctatcaaggacttcaaccgtgaagggctacctcta
atggtctttgctaactggagaggcttctctggtgggatgaaagatatgtatgaccaagtg
ctgaagtttggtgcctatattgtagatggcttgcgggagtgctcacagcctgtgatggtt
tatattcctccccaggctgagctgcggggtggctcttgggttgtgattgaccccaccatc
aacccccggcacatggagatgtatgctgaccgggaaagcaggggatccgttctggaacca
gaagggacagtagaaatcaaattccgcaaaaaggatctggtgaaaaccatgcgtcgggtg
gacccagtctacatccacttggctgagcgattgggcaccccagagctaagcccagctgag
cggaaggaactggagaacaagctgaaagagcgagaggaattcctaattcccatttaccat
caggtagctgtgcagtttgctgacttgcacgacacaccaggccggatgcaggagaagggt
gttattaacgacatcctggattggaaaacatcccgtaccttcttctattggcggctgagg
cgtctcctgctggaggacctggtcaagaagaaaatccacaatgccaacccggaactgact
gatggacagattcaggccatgttgaggcgctggtttgtggaagtagaaggcacagtgaag
gcttatgtttgggacaataataaggatctggtggaatggctggagaaacagctgacagag
gaagatggtgttcggtcagtgatagaggagaacatcaaatacatcagcagggactacatc
ctcaagcaaatccgcagtttggtacaggccaatccagaagttgctatggattccatcgtc
cacatgacccagcacatctcacccactcagcgagcagaagttgtacggatcctctccact
atggattccccttccacatag
DBGET
integrated database retrieval system
