Nannospalax galili (Upper Galilee mountains blind mole rat): 103734261
Help
Entry
103734261 CDS
T03372
Symbol
Top2b
Name
(RefSeq) topoisomerase (DNA) II beta
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
ngi
Nannospalax galili (Upper Galilee mountains blind mole rat)
Pathway
ngi01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
ngi00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
103734261 (Top2b)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
ngi03032
]
103734261 (Top2b)
03036 Chromosome and associated proteins [BR:
ngi03036
]
103734261 (Top2b)
Enzymes [BR:
ngi01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
103734261 (Top2b)
DNA replication proteins [BR:
ngi03032
]
Eukaryotic type
DNA Topoisomerases
103734261 (Top2b)
Chromosome and associated proteins [BR:
ngi03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
103734261 (Top2b)
Centrosome formation proteins
Centriole proteins
103734261 (Top2b)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
Toprim
HATPase_c
DUF7180
Microp_apicomplexa_20
Motif
Other DBs
NCBI-GeneID:
103734261
NCBI-ProteinID:
XP_008831364
UniProt:
A0A8C6WCJ5
LinkDB
All DBs
Position
Un
AA seq
1612 aa
AA seq
DB search
MAKSGGAGGDGTLTWVNNAAKKEESETANRSDASKKLSVERVYQKKTQLEHILLRPDTYI
GSVEPLTQSMWVYDEDVGMNCREVTFVPGLYKIFDEILVNAADNKQRDKNMTCIKVSIDP
ESNIISIWNNGKGIPVVEHRVEKVYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCN
IFSTKFTVETACKEYKHSFKQTWMNNMMKTSEAKIKHFDGEDYTCITFQPDLSKFKMEKL
DKDIVALMTRRAYDLAGSCKGVKVMFNGKKLPVNGFRSYVDLYVKDKLDETGVALKVIHE
LANERWDVCLTLSEKGFQQISFVNSIATTKGGRHVDYVVDQVVGKLIEVVKKKNKAGVSV
KPFQVKNHIWVFINCLIENPTFDSQTKENMTLQPKSFGSKCQLSEKFFKAASNCGIVESI
LNWVKFKAQTQLNKKCSSVKYSKIKGIPKLDDANDAGGKHSLECTLILTEGDSAKSLAVS
GLGVIGRDRYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKSYDDAESLKTL
RYGKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLKHGFLEEFITPIVKASKNKQELSFYS
IPEFDEWRKHIENQKAWKIKYYKGLGTSTAKEAKEYFADMERHRILFRYAGPEDDAAITL
AFSKKKIDDRKEWLTNFMEDRRQRRLHGLPEQFLYGTATKHLTYNDFINKELILFSNSDN
ERSIPSLVDGFKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSAYHHGEQALMMTIVNL
AQNFVGSNNINLLQPIGQFGTRLHGGKDAASPRYIFTMLSSLARLLFPAVDDNLLKFLYD
DNQRVEPEWYIPIIPMVLINGAEGIGTGWACKLPNYDAREIVNNVRRMLEGLEPHPMLPN
YKNFKGTIQELGQNQYAVSGEIFVVDRNTVEITELPVRTWTQVYKEQVLEPMLNGTDKTP
ALISDYKEYHTDTTVKFVVKMTEEKLAQAEAAGLHKVFKLQTTLTCNSMVLFDHMGCLKK
YETVQDILKEFFDLRLSYYGLRKEWLVGMLGAESTKLNNQARFILEKIQGKITIENRSKK
DLIQMLVQRGYESDPVKAWKEAQEKAAEEEDTQNQHDDGSSDSGAPSGPDFNYILNMSLW
CLTKEKVEELIKQRDTKGREVNDLKRKSPSDLWKEDLAAFVEELDKVEAQEREDILAGMS
GKAIKGKVGKPKVKKLQLEETMPSPYGRRIVPEITAMKADASRKLLKKKKGDSDTTVVKV
EFDEEFSGAPVEGAGEEAMTPSAPVNKGPKAKRERKEPGTRVRKTPASSGKPSAKKVKKR
NPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDADDDDDNNDLE
ELKVKASPITNDGEDEFVPSDGLDKDEYSFSPGKSKATPEKSSHDKKSQDFGTLFSFPSY
SQKSEDDSAKFDSNEEDAASVFVPSFGLKQTDKVPSTTAAAKKGKPPSDTAPKAKRAPKQ
KKVVETVNSDSDSEFGIPKKTTAPKGKGRGAKKRKASGSENEGDYNPGRKTSRTTSKKPK
KTSFDQDSEVDMFPSDFTSEPPTLPRTGRARKEVKYFAESDEEEDVDFAMFD
NT seq
4839 nt
NT seq
+upstream
nt +downstream
nt
atggccaagtccggcggtgcgggcggcgacgggaccctgacctgggtgaacaatgctgca
aaaaaagaagagtcagaaacggcgaacaggagtgacgcttcaaagaagctgtctgtcgag
agagtgtaccagaagaagacacagctggagcacattcttcttcgtcctgacacatacatt
ggatcagtggagccactgacacagtcaatgtgggtgtatgatgaagatgtagggatgaac
tgcagagaagtcacctttgttccagggttgtacaagatctttgatgaaattctggttaat
gctgcagacaataagcagagggacaagaacatgacctgcattaaggtttctattgatcct
gaatctaacatcatcagcatttggaataatgggaaaggcattccagtagtggagcacagg
gtagagaaagtttatgttcccgctctgatctttggacagcttttaacatccagtaactat
gatgatgatgagaaaaaagttacaggtggccgcaacggttatggtgcaaaactttgtaat
atttttagtacaaagtttacagtagaaacagcttgtaaggagtacaaacatagctttaag
cagacatggatgaataatatgatgaagacttctgaagccaaaatcaagcattttgatggt
gaagattacacatgcataacattccaaccagacctgtccaagtttaagatggagaaactt
gacaaggacatcgtagccctcatgaccagaagagcatatgacttggctggttcctgtaaa
ggtgtcaaagtcatgttcaatgggaaaaagctgcctgtaaatggatttcgaagttacgta
gacctgtatgtgaaagacaaattggatgaaactggggtagccctgaaagttattcatgaa
cttgcaaatgagagatgggatgtttgtctcactttgagtgagaaaggattccagcagatc
agcttcgtgaatagcattgcaaccacaaaaggtggacggcatgtggattatgtggtagat
caggttgttggtaaactgattgaagtcgtgaagaagaagaacaaagctggtgtgtcggtg
aagccgtttcaggtcaaaaaccatatatgggtttttattaattgtctcattgaaaatcca
acctttgattctcagactaaggaaaacatgactctgcagcccaaaagttttgggtccaaa
tgccaactctcagaaaaattttttaaagcagcctctaattgtggcattgtagaaagtata
ttgaactgggtgaagtttaaggctcaaactcagctgaataagaagtgttcatcagtgaaa
tacagtaaaatcaaaggcattcccaaactggatgatgccaatgatgctggtggcaaacat
tccctggaatgtacactgatattaacagagggggactcggccaaatcgctagctgtgtct
ggattaggtgtgatcgggagagacagatacggagtcttcccactcaggggtaaaattctc
aatgtccgagaagcttctcataaacagatcatggaaaatgcagaaataaacaacattatt
aaaatagttggtttgcaatacaaaaaaagttatgatgacgcagaatccctgaaaaccttg
cgttatgggaagattatgatcatgactgatcaggatcaggatggttctcacatcaaaggc
ctgcttattaattttatccatcataactggccatcacttttgaagcacggctttcttgaa
gagttcatcactcccattgtcaaggcaagcaaaaataagcaggaactttccttttatagt
attcctgagtttgatgagtggagaaagcacatagaaaaccagaaagcctggaagataaaa
tattacaaaggattaggtaccagtacagctaaagaagcaaaggaatattttgctgatatg
gaaaggcatcgcattttgtttagatatgcgggtcccgaagatgatgctgccattaccttg
gcttttagtaagaagaagattgatgacagaaaagagtggctaacaaactttatggaggac
cggagacagcgtaggttacacggcctaccagagcaatttctatatggtacagcaacaaag
catttgacttacaatgatttcatcaacaaagaattgattctcttctcaaactcagataat
gagcgatctataccatctcttgtggatggctttaaaccaggccaacgaaaagttttgttc
acctgtttcaagaggaatgataaacgtgaagtcaaagtcgcccagctagctggatctgtt
gctgaaatgtctgcttatcatcatggagaacaagccttgatgatgacgattgtgaatctg
gcccagaactttgtgggaagtaacaacattaacttgctccagcccatcggtcagtttgga
actcggcttcatggtggcaaagatgctgcgagccctcgttacattttcacaatgttaagc
tccctagcaagactactttttccagctgtggatgataacttgcttaagttcctttatgat
gataatcagcgtgttgagcccgagtggtacatccccatcatccccatggttttgattaat
ggtgccgagggcattgggacgggatgggcttgtaagctgcccaactatgacgccagagag
attgtgaacaatgtcagacggatgctggaagggctggagccccatccaatgcttccaaac
tataagaacttcaaaggcaccatccaggaacttggtcagaaccagtatgctgtcagtggt
gagatatttgtggtggatagaaacacagtagaaattacggagcttcctgtcagaacgtgg
acacaggtgtacaaggagcaggttctagaacctatgctaaatggaacagataaaaccccc
gcactaatttctgattacaaggagtatcatactgacacaactgtgaaatttgtggtgaaa
atgacggaggagaagcttgcacaagcagaagctgctgggctgcataaagtttttaaactt
caaactactctcacttgcaattccatggtactctttgaccatatgggatgtctgaagaag
tatgaaactgtgcaagacattctgaaagaattctttgatttacggttaagttattatggt
ttgcggaaagaatggctcgtaggaatgttgggagcagaatctacaaagcttaacaatcaa
gcccgtttcattttagagaagatacaagggaaaattacaatagagaataggtcaaagaaa
gatttgattcaaatgttagtccagagaggttatgaatctgacccagtgaaagcgtggaaa
gaagcacaagaaaaggcagcggaagaggaagacacacaaaaccagcatgatgatggttcc
tctgactcgggagctccctcaggccctgattttaattatattttaaatatgtctctgtgg
tgtcttactaaagaaaaagttgaagaactcattaaacagagagatacaaaagggcgagag
gtcaatgatctcaaacgaaaatctccttcagatctttggaaagaagatttagcagcattt
gttgaagaattggataaagtggaagcacaagaacgagaagatattctggcaggaatgtct
ggaaaagcaataaaaggtaaagtcggcaaacctaaggtgaagaagctccagttggaggag
acgatgccctcaccgtatgggaggagaattgttcctgagattacagctatgaaggcagac
gccagcagaaagttgctgaagaagaagaagggtgattctgataccacagtagtaaaagta
gaatttgatgaggaattcagtggagcaccagtagaaggtgcaggagaagaggcaatgacc
ccatcagctcctgtaaataaaggtcccaaagccaaaagggagagaaaggagcctgggacc
agggttaggaaaacacctgcgtcatctggtaaacctagtgcgaagaaagtgaagaaacga
aacccttggtcagatgatgagtccaagtcagagagcgacttggaagaaacggagcctgtg
gtgattccaagagactctttgcttaggagagcagctgctgaaagacccaagtacacgttt
gatttctcagaagaggaggacgatgatgctgatgatgatgacgacaataatgacctagaa
gaactgaaagttaaagcatctcccataacaaacgatggggaggatgaatttgttccttca
gatggcttagataaagacgagtattcattttctccaggcaaatcaaaagctactccagaa
aaatcttcacatgataaaaaaagtcaggattttgggactctcttctcatttccttcgtat
tcgcagaagtcggaagacgattcagctaaatttgacagtaatgaagaagatgctgcttct
gtgtttgtaccatcatttggtctgaaacaaacagacaaagttccaagtacgacagcagct
gctaaaaagggtaaaccaccttcagatacagccccgaaggccaagagagctcccaagcag
aagaaagttgtagaaactgtgaactcggactcagactctgaatttggcatcccaaagaag
accacggcacccaaaggtaaaggccgaggggcaaagaaaaggaaagcatctggctctgaa
aatgaaggtgactataatcccggcagaaaaacgtccagaacaaccagcaagaaaccgaag
aaaacatcttttgatcaggattcagaggtagacatgttcccttcagacttcacttctgaa
ccacccactctgccgaggactggtcgggctcggaaagaagtaaaatactttgcagagtct
gatgaggaagaagatgtcgattttgcaatgtttgattaa
DBGET
integrated database retrieval system
