KEGG   Nannospalax galili (Upper Galilee mountains blind mole rat): 103734428
Entry
103734428         CDS       T03372                                 
Symbol
Mgst1
Name
(RefSeq) microsomal glutathione S-transferase 1
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
ngi  Nannospalax galili (Upper Galilee mountains blind mole rat)
Pathway
ngi00480  Glutathione metabolism
ngi00980  Metabolism of xenobiotics by cytochrome P450
ngi00982  Drug metabolism - cytochrome P450
ngi00983  Drug metabolism - other enzymes
ngi01100  Metabolic pathways
ngi01524  Platinum drug resistance
ngi05200  Pathways in cancer
ngi05204  Chemical carcinogenesis - DNA adducts
ngi05207  Chemical carcinogenesis - receptor activation
ngi05208  Chemical carcinogenesis - reactive oxygen species
ngi05225  Hepatocellular carcinoma
ngi05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ngi00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    103734428 (Mgst1)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    103734428 (Mgst1)
   00982 Drug metabolism - cytochrome P450
    103734428 (Mgst1)
   00983 Drug metabolism - other enzymes
    103734428 (Mgst1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    103734428 (Mgst1)
   05204 Chemical carcinogenesis - DNA adducts
    103734428 (Mgst1)
   05207 Chemical carcinogenesis - receptor activation
    103734428 (Mgst1)
   05208 Chemical carcinogenesis - reactive oxygen species
    103734428 (Mgst1)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    103734428 (Mgst1)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    103734428 (Mgst1)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    103734428 (Mgst1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:ngi02000]
    103734428 (Mgst1)
Enzymes [BR:ngi01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     103734428 (Mgst1)
Transporters [BR:ngi02000]
 Other transporters
  Pores ion channels [TC:1]
   103734428 (Mgst1)
SSDB
Motif
Pfam: MAPEG
Other DBs
NCBI-GeneID: 103734428
NCBI-ProteinID: XP_008831575
UniProt: A0A8C6RGQ2
LinkDB
Position
Un
AA seq 155 aa
MADLKQLMDHEVLMAFASYATIILCKMMLLSPATAFQRLTKKVFANPEDTAGFGKGENAK
KFLRTDDRVERVRRAHLNDLENIVPFLGIGLLYSLSGPDLSTALMHFRIFLGARIYHTIA
YLTPLPQPNRALAFIIGYGVTLSMAYRLLRSRLYL
NT seq 468 nt   +upstreamnt  +downstreamnt
atggctgacctcaagcagctcatggaccatgaagtcttgatggcatttgcctcctatgct
accatcatcctttgtaagatgatgctcttgagccctgcaacagcgttccagagattgaca
aaaaaggtttttgccaacccagaagacactgcaggctttggtaagggagagaatgccaag
aagtttcttcgaacagatgacagggtggaacgcgtgcgaagagctcacctcaatgacctt
gaaaacatcgttccctttcttggtatcggcctcctgtattccttgagtggtccagatctc
tctacagccctaatgcacttcagaatctttttgggagctcggatctaccacactattgca
tatttgactcctcttccccagccaaacagagccttggcatttattattggctatggagtt
actttgtcgatggcctacaggctgctaagaagtagattgtacctgtaa

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