Nannospalax galili (Upper Galilee mountains blind mole rat): 103736448
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Entry
103736448 CDS
T03372
Symbol
Gart
Name
(RefSeq) phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
ngi
Nannospalax galili (Upper Galilee mountains blind mole rat)
Pathway
ngi00230
Purine metabolism
ngi00670
One carbon pool by folate
ngi01100
Metabolic pathways
ngi01523
Antifolate resistance
Module
ngi_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
ngi00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
103736448 (Gart)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
103736448 (Gart)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
103736448 (Gart)
Enzymes [BR:
ngi01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
103736448 (Gart)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
103736448 (Gart)
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
103736448 (Gart)
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Ortholog
Paralog
GFIT
Motif
Pfam:
GARS_A
Formyl_trans_N
GARS_N
AIRS_C
GARS_C
AIRS
ATP-grasp
CPSase_L_D2
ATP-grasp_3
Dala_Dala_lig_C
ATP-grasp_2
ATP-grasp_4
RimK
LUD_dom
ATP-grasp_5
Motif
Other DBs
NCBI-GeneID:
103736448
NCBI-ProteinID:
XP_008834168
UniProt:
A0A8C6QMT9
LinkDB
All DBs
Position
Un
AA seq
1010 aa
AA seq
DB search
MAVRVLVIGSGGREHTLAWKLAQSHHVKEVLVAPGNAGTACCGKISNAAISINDHNVLAQ
FCKDEKIELVVVGPEAPLAAGIVGDLTSAGVRCFGPTAEAARLESSKKFAKEFMDRHGIP
TARWKAFTKPEDACSFIMSANFPALVVKASGLAAGKGVIVAKNKEEACKAVQEIMQEKSF
GAAGETIVVEEFLEGEEVSCLCFTDGKTVAPMPSAQDHKRLLDGDQGPNTGGMGAYCPTP
QVPKELLLKIKSSVLQRTVDGMQQEGTPYTGILYAGIMLTKDGPKVLEFNCRFGDPECQV
ILPLLKSDLYEVIQSTLDGLLSTSLPVWLENHSAITVVMASKGYPGAYIKGVEITGFPEA
QALGLEVFHAGTALKDGKVVTSGGRVLTVTAMRENLLSALEEARRGLAAIKFEGAVYRTD
IGFRAIAFLQQPRALTYKESGVDIAAGNTLVKKIQPLAKATSRPGCSVDLGGFAGLFDLK
AAGFKDPLLASGTDGVGTKLKIAQLCNRHDTIGQDLVAMCVNDILAQGAEPLFFLDYFSC
GKLDLSTTEAVVAGVAKACGQAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMERDQKLP
HLERITEGDVVVGVASSGLHSNGFSLVRKIVAKSSLQYSSPAPDGCGHQSLGDLLLTPTK
IYSQSLLPIIRSGHVKAFAHITGGGLLENIPRVLPQKFGVDLDACTWRIPKVFSWLQWEG
QLSEEEMARTFNCGVGAALVVSKDQAEQILRDIRQHQEEAWVIGSVVLCPEDSPRVKVKN
LIETMQINRSVLTNGFLTDRFPTQPRKARVAVLISGTGSNLQALIDSTQDTKSSSHIVVV
ISNKAAVAGLEKAERAGIPTRVINHKLYKSRVEFDNAVDQVLEEFSTDIVCLAGFMRILS
GPFVRKWNGKMLNIHPSLLPSFKGSNAHEQVLEAGVTITGCTVHFVAEDVDAGQIILQEA
VPVKRGDTVATLSERVKVAEHKIFPAALQLVASGTVQLGENGKICWVKEK
NT seq
3033 nt
NT seq
+upstream
nt +downstream
nt
atggcagtccgagtccttgtaattggcagtggaggaagggaacatacactggcctggaaa
cttgcacagtctcatcatgtcaaagaagtgttggttgccccaggaaatgcaggcactgcc
tgctgtggaaagatttcaaatgctgccatctccatcaatgatcataatgtccttgctcaa
ttctgcaaagatgagaagattgaacttgtggttgttggaccagaggcccctctagctgct
ggaatcgttggggacctgacttctgcgggagtgcgatgctttggtcccacagcagaagca
gctcggttagagtccagtaaaaagtttgccaaagagtttatggaccgacatggaatccca
acagcacggtggaaagctttcaccaaacctgaagatgcctgtagctttattatgagtgca
aattttcctgctttggttgtgaaggccagtgggcttgcagctggaaagggggtgatagtt
gcaaagaacaaggaggaagcatgcaaagctgtacaggagatcatgcaagaaaaatctttt
ggagcagctggagaaacaattgttgttgaagaatttcttgaaggagaagaagtatcttgt
ctttgtttcactgatgggaagacggtggctcccatgccctcagcacaagaccataaacga
ttactggatggagatcagggccccaacacagggggaatgggagcctattgtccaacacct
caggttcctaaagagttattactaaaaattaaaagcagtgttcttcagaggacagtagat
ggcatgcagcaggagggtacgccttatactggaattctctatgctggtataatgctgacc
aaagatggcccaaaagttctggagtttaattgccgttttggtgatcccgagtgccaagta
atcctcccacttcttaaaagtgatctttatgaagtgattcagtctaccttagatggcctg
ctgagtacatctctccctgtttggctagaaaaccacagtgccataactgttgtcatggca
agtaaaggttatcctggagcctacatcaagggtgtagagataacagggtttcctgaagca
caagctttaggactagaagtgttccatgcaggcactgccctcaaagatggcaaagtagtg
accagcgggggtagagtccttacagtcacagccatgcgggaaaatctcctatcagccctt
gaagaagccaggagaggactggctgctataaagtttgagggggcagtttataggacggac
attggcttccgtgccatagccttcctccagcagcccagggccctgacttataaggaatcg
ggggtagatattgcagccggaaatacgctagttaagaaaattcagcctttagccaaagct
acctcaagaccaggttgcagtgtggatcttggaggttttgctggtctttttgatttgaaa
gcagctggtttcaaagatcctcttctggcctctggaacagatggtgttgggactaaactg
aagatcgcccagctgtgcaataggcatgataccattggtcaggatttggttgcaatgtgc
gtaaatgacattctagcacaaggagcagagcccctcttcttccttgattacttctcctgt
ggaaaacttgacctcagtacgactgaagctgttgtagctggagttgctaaagcttgtggc
caagctggatgtgctctccttggtggggaaacagcagaaatgcctgacatgtatcctcct
ggagagtatgatcttgccgggtttgccgttggtgctatggagcgggatcaaaaactccct
cacctggaaaggatcaccgaaggggatgttgttgttggagtagcttcatctggtcttcac
agcaatggatttagccttgtgcggaaaattgtggcaaagtcttccctccagtactcctct
ccagcacctgatggttgtggtcaccagtctttaggagacttacttctcactccaaccaag
atctacagccaatcactgttacctatcatacgttcaggacatgtcaaagcctttgctcat
attactggaggaggactgctagaaaatattcccagagtgctccctcagaagtttggagtg
gatttagatgcctgcacctggaggatccctaaggtcttctcatggttacagtgggaagga
cagctctctgaagaagagatggccagaacatttaactgtggagttggagctgcactggtg
gtatccaaggaccaggcagagcagattctgcgtgatattcgacagcaccaggaagaagcc
tgggtaataggcagtgttgttctgtgtcccgaagattctcctcgtgtaaaagtcaagaat
ttgattgaaaccatgcaaataaacaggtcagtgttgacaaatggcttcctgacagatcgt
ttccctacccaaccaagaaaggcaagagtggctgtgctgatatctggaacaggatcaaat
ctccaagccctcatagacagtacacaggatacaaaaagttcttcacacattgttgttgtt
atctccaacaaagctgctgtggctggcttagaaaaagcagaaagagctggtattcccacc
agagtaattaatcataaattatataaaagtcgtgtggaatttgacaatgcagttgaccaa
gtccttgaagagttctctacagacatagtctgtcttgcaggatttatgagaattctgtct
ggcccttttgtcagaaaatggaatgggaaaatgctcaatatccacccatctttgctccct
tctttcaagggttcaaatgctcatgagcaggtcctggaagctggagtcacaatcactggg
tgcactgtacactttgtagctgaagacgtagatgctggacaaattatcttacaagaagca
gttcctgtgaagaggggtgacactgttgcaactttgtctgaaagagtaaaagtagcagaa
cataaaatctttcctgcagccctccagctggtggccagtgggactgtacagcttggagaa
aatggcaagatctgctgggtcaaagagaagtga
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