Nannospalax galili (Upper Galilee mountains blind mole rat): 103737596
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Entry
103737596 CDS
T03372
Symbol
Pde8a
Name
(RefSeq) phosphodiesterase 8A
KO
K18437
high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:
3.1.4.53
]
Organism
ngi
Nannospalax galili (Upper Galilee mountains blind mole rat)
Pathway
ngi00230
Purine metabolism
ngi01100
Metabolic pathways
ngi04927
Cortisol synthesis and secretion
ngi04934
Cushing syndrome
ngi05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
ngi00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
103737596 (Pde8a)
09150 Organismal Systems
09152 Endocrine system
04927 Cortisol synthesis and secretion
103737596 (Pde8a)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
103737596 (Pde8a)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
103737596 (Pde8a)
Enzymes [BR:
ngi01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
103737596 (Pde8a)
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Paralog
GFIT
Motif
Pfam:
PDEase_I
PAS
PAS_9
PDE8A_N
PAS_3
PAS_4
PAS_8
Motif
Other DBs
NCBI-GeneID:
103737596
NCBI-ProteinID:
XP_008835640
LinkDB
All DBs
Position
Un
AA seq
694 aa
AA seq
DB search
MQVYQSIKTLRKHGYCWCSTKDGQGRVVFNALHCCWLHTGEEANSGRRYIENPSIMACYN
ELLQLAFGEVRSQLKLRACNSIFTALERSQEAIEITSEDHIIQYANPAFETTMGYQSGEL
IGKELAQVPINEKKGDLLDAINSCIKIGKEWQGVYHTQKKNGDNIQQNVKIIPVTGQGGK
IRHYVSIIRVCNDNNKVEKVSDGVLTDSQTDNQSGKHKDRRKSSVDMKAVASRASEVSNQ
RRNSSLARVHSMMIEAPINKVISIISAAQENSPMPVIEALNRVLEILRTTELYSPQFNTE
EDDPHAVNLVGGLMSDGLRRFSGTEYVLSTKNIQQASSSMIIPLSLHDIPPRIALAIENE
EYWDFDIFELEAATQNRPLIYLGLKTFARFGICEFLQCSESTLRSWFQIIEANYHSSNPY
HNSTHSADVLHATAYFLSRDKIKETLDPIDEVAALIAATIHDVDHPGRTNSFLCNAGSEL
AILYNDTAVLESHHAALAFQLTLENDKCNIFKNMERNEYRTLRQGIIDMVLATEMTKHFE
HVNKFINSINKPLTTLKEKEEIGKDQGAISAMLKTPENRALIKRMMIKCADVSNPCRPLE
YCIEWAARISEEYFSQTDEEKQLDLPVVMPVFDRNTCSIPKSQISFIDYFITNMFYAWHA
FVNLPILMQHLDDNYKYWKGLDEKKLRSLRPPPE
NT seq
2085 nt
NT seq
+upstream
nt +downstream
nt
atgcaggtctatcagagcatcaaaactctcagaaaacacggttattgttggtgtagtaca
aaggatggacaaggaagagttgtctttaatgcccttcattgctgctggcttcacacgggt
gaggaagcaaactcaggaaggaggtatatagaaaaccccagtatcatggcctgttacaac
gaactgctccagttggcgtttggagaggtgcgatcacagctcaaactcagggcttgtaac
tcaatatttactgcattagagaggagtcaagaagcaattgaaattacaagtgaagaccac
attatacagtatgcaaatcctgcatttgaaacaacaatgggctaccaatcaggtgaatta
atagggaaggagttagcacaagtgcccataaatgaaaaaaaaggtgacttgcttgatgcc
ataaactcatgcatcaagataggcaaggagtggcaaggagtttaccatacccaaaagaaa
aatggagataatatacaacagaacgtgaagataatacctgtcactgggcagggaggaaaa
atcaggcactatgtgtccattatcagagtgtgcaatgataacaataaggttgagaaagta
tctgatggtgttctgaccgacagtcaaacagataatcagtcaggcaaacataaagacagg
aggaaaagctcagtggacatgaaggctgttgcttctcgagcaagtgaagtttccaaccag
aggagaaattcctccttggcccgggtacattcaatgatgattgaggcacccatcaacaag
gtaatcagtattatcagtgctgcccaggagaacagtcctatgcctgtgatagaagccttg
aaccgtgtgctggaaattctgagaaccactgagttatattcaccacagtttaatactgaa
gaagatgatcctcatgccgtcaacctcgtagggggcttaatgtctgacggtttacgaaga
ttttcaggaactgagtatgttctttcaacaaaaaacattcagcaggcttcaagcagtatg
atcatccccctctcccttcatgatattccacctcggattgccctggccatagaaaatgaa
gaatattgggactttgacatttttgagctagaggctgccacccaaaataggcctttgatt
tatctaggtctcaaaacatttgctcgctttggaatctgtgaattcttacagtgctccgag
tcaacattgagatcgtggttccaaattattgaagccaattatcattcttctaacccttac
cacaattctacacattctgcagatgtgcttcacgccactgcctatttcctttccagggac
aaaataaaggaaactttagatccaattgatgaggttgctgccctcatcgctgccaccatt
cacgatgtggatcaccctgggagaaccaactcgttcctttgcaatgcaggaagtgagctg
gccattttatacaatgacactgctgtgctggagagccaccatgcagccctggccttccag
ctgactcttgaaaatgacaagtgcaatatctttaaaaacatggagaggaatgagtaccgg
accctacgccagggtattattgacatggtcctagccacagaaatgacaaagcattttgaa
catgtcaacaagtttatcaacagtatcaacaagcccttgacaacactaaaagaaaaagag
gaaattggcaaagaccaaggagctataagtgctatgctcaagactccagagaaccgggct
ctcatcaaacgaatgatgatcaagtgtgccgatgtgtccaatccctgccggcccctggag
tactgcatcgagtgggctgcacgcatttcagaagaatatttttctcagactgatgaagag
aagcagctggacttgcctgtagtgatgccagttttcgacagaaacacctgcagcatcccc
aaatctcaaatctctttcattgactacttcatcacaaacatgttttacgcctggcatgcc
tttgtgaacctgcctattttaatgcagcacttggatgataactacaagtactggaaagga
ctggatgaaaagaagctgcggagcctccgaccccctccagaatag
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