Nannospalax galili (Upper Galilee mountains blind mole rat): 103739078
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Entry
103739078 CDS
T03372
Symbol
Atp2a2
Name
(RefSeq) ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2
KO
K05853
P-type Ca2+ transporter type 2A [EC:
7.2.2.10
]
Organism
ngi
Nannospalax galili (Upper Galilee mountains blind mole rat)
Pathway
ngi04020
Calcium signaling pathway
ngi04022
cGMP-PKG signaling pathway
ngi04024
cAMP signaling pathway
ngi04148
Efferocytosis
ngi04260
Cardiac muscle contraction
ngi04261
Adrenergic signaling in cardiomyocytes
ngi04380
Osteoclast differentiation
ngi04919
Thyroid hormone signaling pathway
ngi04972
Pancreatic secretion
ngi05010
Alzheimer disease
ngi05017
Spinocerebellar ataxia
ngi05022
Pathways of neurodegeneration - multiple diseases
ngi05410
Hypertrophic cardiomyopathy
ngi05412
Arrhythmogenic right ventricular cardiomyopathy
ngi05414
Dilated cardiomyopathy
ngi05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
ngi00001
]
09130 Environmental Information Processing
09132 Signal transduction
04020 Calcium signaling pathway
103739078 (Atp2a2)
04024 cAMP signaling pathway
103739078 (Atp2a2)
04022 cGMP-PKG signaling pathway
103739078 (Atp2a2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
103739078 (Atp2a2)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
103739078 (Atp2a2)
09153 Circulatory system
04260 Cardiac muscle contraction
103739078 (Atp2a2)
04261 Adrenergic signaling in cardiomyocytes
103739078 (Atp2a2)
09154 Digestive system
04972 Pancreatic secretion
103739078 (Atp2a2)
09158 Development and regeneration
04380 Osteoclast differentiation
103739078 (Atp2a2)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
103739078 (Atp2a2)
05017 Spinocerebellar ataxia
103739078 (Atp2a2)
05022 Pathways of neurodegeneration - multiple diseases
103739078 (Atp2a2)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
103739078 (Atp2a2)
05412 Arrhythmogenic right ventricular cardiomyopathy
103739078 (Atp2a2)
05414 Dilated cardiomyopathy
103739078 (Atp2a2)
05415 Diabetic cardiomyopathy
103739078 (Atp2a2)
Enzymes [BR:
ngi01000
]
7. Translocases
7.2 Catalysing the translocation of inorganic cations
7.2.2 Linked to the hydrolysis of a nucleoside triphosphate
7.2.2.10 P-type Ca2+ transporter
103739078 (Atp2a2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
E1-E2_ATPase
Cation_ATPase_C
Cation_ATPase
Cation_ATPase_N
Hydrolase
Hydrolase_3
HAD
Motif
Other DBs
NCBI-GeneID:
103739078
NCBI-ProteinID:
XP_017655193
UniProt:
A0A8C6RY02
LinkDB
All DBs
Position
Un
AA seq
1043 aa
AA seq
DB search
MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDL
LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK
EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSIL
TGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV
ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV
ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
MSVCRMFILDKVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVKCHQYDGLVELATICALC
NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMK
KEFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTPGV
KQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGMLD
PPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDEL
SPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKSEIGIAMG
SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAAL
GFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIG
CYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKEDNPDFDGVDCAIFESPYPMTMAL
SVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITP
LNLTQWLMVLKISLPVILMDETLKFVARNYLEPGKECVQPATKSSCSFSACTDGISWPFV
LLIMPLVVWVYSTDTNFSDMFWS
NT seq
3132 nt
NT seq
+upstream
nt +downstream
nt
atggagaacgctcacacaaagacggtggaggaggttctgggccacttcggcgtcaacgag
agcaccgggctaagcctggagcaggtcaagaagctcaaggagagatggggctccaacgaa
ttaccggctgaagaaggaaaaaccttgctggaacttgtgattgagcagtttgaagactta
ctagttagaattttattgttggcagcatgtatatcttttgttttggcttggtttgaagaa
ggtgaagaaacaattacagcctttgtagaaccttttgtaattctacttatattagtagcc
aatgcaattgtgggtgtgtggcaggaaagaaatgctgaaaatgcaatagaagcccttaag
gagtatgaacctgaaatgggcaaagtgtatcgacaggacagaaagagtgtacagcggatt
aaagctaaagacatagttccgggtgatatagtagaaattgctgttggtgacaaagttcct
gctgatataagattaacttccatcaagtctacaactctaagagttgaccagtcaattctc
acaggtgaatcagtttcagtcataaagcacactgaccctgtccctgacccacgtgccgtc
aatcaagataagaagaatatgctcttttctggtacaaacattgctgctgggaaagccatg
ggagtggtggtggccactggagttaatactgaaattggcaagatccgggatgaaatggtt
gcaacggaacaggagagaacaccactgcagcagaagttagatgagtttggggaacagctt
tccaaagttatctccctcatttgcattgcagtctggatcataaacattgggcatttcaat
gacccagttcatggaggctcctggatcagaggtgctatctattactttaagattgcagtg
gccttagctgttgctgccatccctgagggtctgcctgctgtcatcactacctgtttggct
cttggaactcgaagaatggcgaaaaaaaatgccattgttcgaagcctaccttctgtggaa
acccttggttgtacttctgttatttgctcagacaaaacaggcacacttacgacaaaccag
atgtcagtttgcaggatgttcattctggacaaagttgaaggtgatacttgttcccttaat
gagtttaccataactggatcaacatatgcacccattggagaagtgcataaagatgataag
ccagtgaaatgtcatcagtatgatggtcttgtagaattagcaacaatctgtgccctttgt
aatgactctgctttggattacaatgaggcaaagggtgtgtatgaaaaagttggagaagct
acagagactgctctcacctgcttggtagagaagatgaatgtatttgatacggaattaaaa
gggctttctaaaatagaacgtgcaaatgcctgcaactcggtcatcaaacaattgatgaaa
aaggagtttactctggagttttcacgagatagaaaatcaatgtcagtctattgtacacca
aacaagccaagcaggacatccatgagcaagatgtttgtgaagggtgctcctgaaggtgtc
atcgacaggtgtacccacattcgagttggaagtacaaaggtccccatgacccctggtgtc
aaacagaagatcatgtctgtcattcgggagtggggcagtggtagtgacacactgcgatgc
ctggctctcgccactcatgacaacccactaaggagagaggagatgcacctggaggattcc
gccaacttcatcaaatatgagaccaatctgacattcgttggctgtgtgggcatgctggat
cctcccagaatcgaagtggcctcctctgtgaagctgtgccgtcaagcaggcatccgtgtc
atcatgatcacaggggacaacaagggcactgctgtggccatctgtcgtcgcattggtatc
tttgggcaggatgaggatgtgacatcaaaggcttttacagggcgggaatttgatgagctc
agtccctcagcccagagagatgcctgcttgaacgcccgctgttttgctcgagttgaacct
tcccacaaatctaaaattgtcgagttccttcagtcctttgatgagatcacagctatgact
ggtgatggtgtgaatgatgctcctgccttgaagaaatctgagattggcattgccatgggt
tctggcactgcagtggctaaaactgcctcagagatggtcctggcagatgacaacttctcc
accattgtggcagctgtcgaggaggggcgagccatctacaacaacatgaagcagtttatc
cgatacctcatctcatccaacgtcggggaggttgtctgtattttcctgacagcagctctt
ggatttcctgaggctttaattcctgtccaactactctgggtcaacctggtgacagatggt
ctgcctgccactgctctggggttcaaccctccggacctggacatcatgaataaacctccc
cggaacccgaaggaaccgctcatcagtggatggctctttttccgttacttagctattggc
tgttatgttggtgctgccactgtgggtgctgctgcatggtggttcattgctgctgatggt
ggtccaagagtgtccttctaccagctgagtcatttcctacagtgtaaagaggacaaccca
gactttgatggagtggattgtgcaatctttgagtctccgtacccaatgacaatggcactt
tctgttctagtaaccatagagatgtgtaatgccctcaacagcttgtctgaaaaccagtcc
ttgctgaggatgcctccttgggagaatatctggcttgtgggctccatctgcttgtccatg
tcgctccacttcctgatcctctatgtagaacccttgccactcatcttccagatcacacca
ctgaatttgacccaatggctgatggtgctgaaaatctccttgcctgtgatcctcatggat
gagaccctcaagtttgtggcccggaactacctggaacccggtaaagagtgtgtacagcct
gccaccaaatcctcctgctcgttttcagcatgcaccgatggcatttcctggccgtttgtg
ctgctcattatgcccctggtggtctgggtctacagcacagacactaactttagtgatatg
ttctggtcttga
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