Nannospalax galili (Upper Galilee mountains blind mole rat): 103739411
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Entry
103739411 CDS
T03372
Symbol
Adcy4
Name
(RefSeq) adenylate cyclase 4
KO
K08044
adenylate cyclase 4 [EC:
4.6.1.1
]
Organism
ngi
Nannospalax galili (Upper Galilee mountains blind mole rat)
Pathway
ngi00230
Purine metabolism
ngi01100
Metabolic pathways
ngi01522
Endocrine resistance
ngi04015
Rap1 signaling pathway
ngi04020
Calcium signaling pathway
ngi04022
cGMP-PKG signaling pathway
ngi04024
cAMP signaling pathway
ngi04062
Chemokine signaling pathway
ngi04072
Phospholipase D signaling pathway
ngi04081
Hormone signaling
ngi04082
Neuroactive ligand signaling
ngi04114
Oocyte meiosis
ngi04211
Longevity regulating pathway
ngi04213
Longevity regulating pathway - multiple species
ngi04261
Adrenergic signaling in cardiomyocytes
ngi04270
Vascular smooth muscle contraction
ngi04371
Apelin signaling pathway
ngi04540
Gap junction
ngi04611
Platelet activation
ngi04713
Circadian entrainment
ngi04714
Thermogenesis
ngi04723
Retrograde endocannabinoid signaling
ngi04724
Glutamatergic synapse
ngi04725
Cholinergic synapse
ngi04727
GABAergic synapse
ngi04742
Taste transduction
ngi04750
Inflammatory mediator regulation of TRP channels
ngi04911
Insulin secretion
ngi04912
GnRH signaling pathway
ngi04913
Ovarian steroidogenesis
ngi04914
Progesterone-mediated oocyte maturation
ngi04915
Estrogen signaling pathway
ngi04916
Melanogenesis
ngi04918
Thyroid hormone synthesis
ngi04921
Oxytocin signaling pathway
ngi04923
Regulation of lipolysis in adipocytes
ngi04925
Aldosterone synthesis and secretion
ngi04926
Relaxin signaling pathway
ngi04927
Cortisol synthesis and secretion
ngi04928
Parathyroid hormone synthesis, secretion and action
ngi04934
Cushing syndrome
ngi04935
Growth hormone synthesis, secretion and action
ngi04970
Salivary secretion
ngi04971
Gastric acid secretion
ngi04972
Pancreatic secretion
ngi04976
Bile secretion
ngi05032
Morphine addiction
ngi05163
Human cytomegalovirus infection
ngi05166
Human T-cell leukemia virus 1 infection
ngi05200
Pathways in cancer
ngi05207
Chemical carcinogenesis - receptor activation
ngi05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
ngi00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
103739411 (Adcy4)
09130 Environmental Information Processing
09132 Signal transduction
04015 Rap1 signaling pathway
103739411 (Adcy4)
04371 Apelin signaling pathway
103739411 (Adcy4)
04020 Calcium signaling pathway
103739411 (Adcy4)
04072 Phospholipase D signaling pathway
103739411 (Adcy4)
04024 cAMP signaling pathway
103739411 (Adcy4)
04022 cGMP-PKG signaling pathway
103739411 (Adcy4)
09133 Signaling molecules and interaction
04082 Neuroactive ligand signaling
103739411 (Adcy4)
04081 Hormone signaling
103739411 (Adcy4)
09140 Cellular Processes
09143 Cell growth and death
04114 Oocyte meiosis
103739411 (Adcy4)
09144 Cellular community - eukaryotes
04540 Gap junction
103739411 (Adcy4)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
103739411 (Adcy4)
04062 Chemokine signaling pathway
103739411 (Adcy4)
09152 Endocrine system
04911 Insulin secretion
103739411 (Adcy4)
04923 Regulation of lipolysis in adipocytes
103739411 (Adcy4)
04912 GnRH signaling pathway
103739411 (Adcy4)
04913 Ovarian steroidogenesis
103739411 (Adcy4)
04915 Estrogen signaling pathway
103739411 (Adcy4)
04914 Progesterone-mediated oocyte maturation
103739411 (Adcy4)
04921 Oxytocin signaling pathway
103739411 (Adcy4)
04926 Relaxin signaling pathway
103739411 (Adcy4)
04935 Growth hormone synthesis, secretion and action
103739411 (Adcy4)
04918 Thyroid hormone synthesis
103739411 (Adcy4)
04928 Parathyroid hormone synthesis, secretion and action
103739411 (Adcy4)
04916 Melanogenesis
103739411 (Adcy4)
04925 Aldosterone synthesis and secretion
103739411 (Adcy4)
04927 Cortisol synthesis and secretion
103739411 (Adcy4)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
103739411 (Adcy4)
04270 Vascular smooth muscle contraction
103739411 (Adcy4)
09154 Digestive system
04970 Salivary secretion
103739411 (Adcy4)
04971 Gastric acid secretion
103739411 (Adcy4)
04972 Pancreatic secretion
103739411 (Adcy4)
04976 Bile secretion
103739411 (Adcy4)
09156 Nervous system
04724 Glutamatergic synapse
103739411 (Adcy4)
04727 GABAergic synapse
103739411 (Adcy4)
04725 Cholinergic synapse
103739411 (Adcy4)
04723 Retrograde endocannabinoid signaling
103739411 (Adcy4)
09157 Sensory system
04742 Taste transduction
103739411 (Adcy4)
04750 Inflammatory mediator regulation of TRP channels
103739411 (Adcy4)
09149 Aging
04211 Longevity regulating pathway
103739411 (Adcy4)
04213 Longevity regulating pathway - multiple species
103739411 (Adcy4)
09159 Environmental adaptation
04713 Circadian entrainment
103739411 (Adcy4)
04714 Thermogenesis
103739411 (Adcy4)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
103739411 (Adcy4)
05207 Chemical carcinogenesis - receptor activation
103739411 (Adcy4)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
103739411 (Adcy4)
05163 Human cytomegalovirus infection
103739411 (Adcy4)
09165 Substance dependence
05032 Morphine addiction
103739411 (Adcy4)
09166 Cardiovascular disease
05414 Dilated cardiomyopathy
103739411 (Adcy4)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
103739411 (Adcy4)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
103739411 (Adcy4)
Enzymes [BR:
ngi01000
]
4. Lyases
4.6 Phosphorus-oxygen lyases
4.6.1 Phosphorus-oxygen lyases (only sub-subclass identified to date)
4.6.1.1 adenylate cyclase
103739411 (Adcy4)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Guanylate_cyc
Adcy_cons_dom
AC_N
HNOBA
CD52
DMF_alpha
Motif
Other DBs
NCBI-GeneID:
103739411
NCBI-ProteinID:
XP_008838013
UniProt:
A0A8C6RVD9
LinkDB
All DBs
Position
Un
AA seq
1068 aa
AA seq
DB search
MARLFSPRPPPSEDLFYETYYSLSQQYPLLLLLLVIVLCALLALPAVAWASGRELTSDTS
FLTTVLCALGGFSLLLGLASREQRLQRWTRPLSGLIWAALLALGHGFLFTGGVVSAWDQV
SFFLFIIFTVYAMLPLGMRDAAAAGLTSSLSHLLVLGLYLGWQPDSQPALLPQLAANAVL
FLCGNVVGAYHKALMERALRATFREALSSLHSRRRLDTEKKHQEHLLLSILPAYLAQEMK
AEIMARLQAGQGSRPENTNNFHSLYVKRHQGVSVLYADIVGFTRLASECSPKELVLMLNE
LFGKFDQIAKEHECMRIKILGDCYYCVSGLPLSLPDHAINCVRMGLDMCRAIRKLRAATG
VDINMRVGVHSGSVLCGVIGLQKWQYDVWSHDVTLANHMEAGGVPGRVHITGATLALLAG
VYAVEDVAMEHRDPYLRELGEPTYLVIDPRAKEEDEKGTAGGLLSSLEGHKMRPSLLMTR
YLESWGAAKPFAHLSHVDSPVSTSTPLPEAFSPQWSLDRSRTPRGLDDELDTGDAKFFQV
IEQLNSQKQWKQSKDFNLLTLYFREKEMEKQYRLSALPAFKYYAACTFLVFLSNFTIQML
VTNRPPALAITYSITFLLFLLLLIVCFSEHLMKCVRKGPKMLHWLPALSGLVATRPGLRV
ALGTATILLVFTMATASLLFLPVSSDCLFLVSNVSSMAFNHSWELPGSLPLISIPYSMHC
CVLGFLSCSLFLHMSFELKLLLLLLWLAASCSLFLHSHAWLSDCLIACLYQGPLNSRPGV
LKEPKLMGAMSFFIFFFTLLVLARQNEYYCRLDFLWKKKLRQEREETETMENLTRLLLEN
VLPAHVAPQFIGQNRRNEDLYHQSYECVCVLFASVPDFKEFYSESNINHEGLECLRLLNE
IIADFDELLSKPKFSGVEKIKTIGSTYMAATGLNATSGQDTQQDAERSCSHLGTMVEFAV
ALGSKLDVINKHSFNNFRLRVGLNHGPVVAGVIGAQKPQYDIWGNTVNVASRMESTGVLG
KIQVTEETARALQSLGYTCYSRGIIKVKGKGQLCTYFLNTDLTRTGPP
NT seq
3207 nt
NT seq
+upstream
nt +downstream
nt
atggcccgtctcttcagcccccggcctccccccagcgaagacctcttctatgagacctac
tacagcctgagccaacagtacccgctgttgctactgcttctggtgatcgtgctgtgcgcg
ctcctggcactgcccgccgtcgcctgggccagcggcagggagctgacctcagacacaagc
ttcctgaccactgtgctgtgcgctttgggtggcttctcgctgttgttggggctagcttct
agagagcaaagactgcagcgctggacacgacctctctctggcctaatatgggctgcactg
ctggccctaggccatggcttcctgttcacggggggcgtagtaagtgcctgggaccaggtg
tcatttttcctcttcatcatctttactgtgtacgccatgttgcccttgggcatgcgggat
gctgccgcagcaggcctcacctcgtcactctcacacctgcttgtccttgggctgtacctc
ggatggcagcccgattcacagcccgcactgctaccacagctggcagcaaatgcagtgttg
ttcctgtgtgggaatgtggtgggagcgtaccacaaggccctgatggaacgagctttgcgt
gccacattccgggaagcactcagctccctgcactcacgccggaggctggacacagagaaa
aagcaccaggagcaccttctcttgtccatccttcctgcctacctggcccaagagatgaaa
gcagagatcatggcacggctgcaggctggacagggctcacgaccggagaacacaaacaat
ttccacagcctatatgtcaagaggcaccaaggagttagtgtgctgtacgctgacattgtg
ggcttcacacggctagccagcgagtgctcccctaaggagctggtactcatgctcaacgag
ctcttcggcaagtttgaccagattgccaaggagcacgaatgcatgcggatcaagatccta
ggggactgttactactgtgtctccgggctgccactctcgctgccagaccatgccatcaac
tgtgtacgcatgggactggacatgtgccgggccatcaggaaacttcgggcagccactggt
gtagacatcaacatgcgtgtgggtgtgcattcaggcagtgtgctctgtggagtcatcggg
ctacagaagtggcagtatgatgtctggtctcatgacgtcacattggccaaccacatggag
gcaggtggtgtaccagggcgagtgcatatcacaggcgctaccctggccttgctggcagga
gtttatgctgtggaggacgtagccatggaacaccgagacccataccttcgggagctaggc
gagcctacatacctggtcattgatcctcgggccaaagaggaagatgagaagggcacagca
ggagggttactgtcctctttggagggccacaagatgcgcccatcactactgatgacccgt
tacctagagtcttggggtgcagccaaacctttcgcccacctgagccacgttgacagtcct
gtatccacttccactccgctcccggaggccttcagcccccagtggagcctggaccggagc
cgcacccctcggggactagacgatgagctggatactggggatgccaagttcttccaggtc
atcgagcaactcaactctcagaaacaatggaagcagtcaaaggacttcaacctactgaca
ctgtacttcagagagaaggagatggagaaacagtatcggctctctgcactccctgccttc
aagtactatgcagcctgcaccttcctggtttttctgtccaacttcactatccaaatgctg
gtgacaaacaggcccccagctctggccatcacctacagcatcacgttcctcctcttcctt
ctcctcctcatcgtctgcttctcagagcacctgatgaagtgtgtgcggaaaggtcccaag
atgctacactggctgcctgcactgtctggcctggtggccacaaggccaggacttcgagtg
gccctgggcactgccaccatcctcctggtcttcaccatggccactgccagcctgctcttc
ctaccggtgtcatcagactgcctcttcctggtttccaatgtttcttccatggctttcaat
cactcctgggagcttcctggatccctgcctctcatcagcatcccatactccatgcactgt
tgtgtgctgggtttcctctcctgctccctctttctgcacatgagcttcgaactgaagctg
ttgctgctcctgctgtggctggcagcatcttgttccctcttcctgcactcccacgcctgg
ctgtctgattgcctcatcgcctgcctttatcaaggccctttgaactccaggccaggagtg
ctgaaggagcccaaactgatgggagcgatgtcctttttcatcttcttcttcaccctcctt
gtcctggctcggcagaatgagtattactgccgcttggacttcctgtggaagaagaaactg
aggcaggagcgtgaggagacagagacgatggagaacttgacccggctactcctggagaat
gtgctccctgcccacgtggccccccagttcattggccagaaccggcgcaacgaggacctt
taccaccagtcgtacgaatgtgtttgtgtgctctttgcatcagtcccagactttaaggaa
ttctactcagaatccaacatcaaccacgagggactagagtgtctgaggctgcttaatgag
atcattgctgattttgatgagctgctctccaagccaaaattcagtggggtggagaagatc
aaaactattggcagtacctacatggcagccacaggcttaaatgccacatctggacaggac
acacaacaggatgctgaaagaagttgcagccatctgggcaccatggtggaatttgcagtg
gccctggggtctaaactggatgtcatcaacaagcactcattcaacaacttccgcctgcgt
gtagggttgaaccatggaccagtagtggctggagtgattggggcccagaagccacaatat
gacatctggggcaacacagtgaatgtagccagccgcatggagagtacaggagtccttggc
aagatccaagtgactgaggagacagccagggccctgcagtccctgggttatacatgctac
agccggggtatcatcaaggtcaaaggcaaagggcagctctgcacctacttcttgaacaca
gacttgacacgaactggacctccctaa
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