KEGG   Nannospalax galili (Upper Galilee mountains blind mole rat): 103739659
Entry
103739659         CDS       T03372                                 
Symbol
Mapk13
Name
(RefSeq) mitogen-activated protein kinase 13
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
ngi  Nannospalax galili (Upper Galilee mountains blind mole rat)
Pathway
ngi01522  Endocrine resistance
ngi04010  MAPK signaling pathway
ngi04015  Rap1 signaling pathway
ngi04068  FoxO signaling pathway
ngi04071  Sphingolipid signaling pathway
ngi04114  Oocyte meiosis
ngi04148  Efferocytosis
ngi04218  Cellular senescence
ngi04261  Adrenergic signaling in cardiomyocytes
ngi04370  VEGF signaling pathway
ngi04380  Osteoclast differentiation
ngi04550  Signaling pathways regulating pluripotency of stem cells
ngi04611  Platelet activation
ngi04613  Neutrophil extracellular trap formation
ngi04620  Toll-like receptor signaling pathway
ngi04621  NOD-like receptor signaling pathway
ngi04622  RIG-I-like receptor signaling pathway
ngi04625  C-type lectin receptor signaling pathway
ngi04657  IL-17 signaling pathway
ngi04658  Th1 and Th2 cell differentiation
ngi04659  Th17 cell differentiation
ngi04660  T cell receptor signaling pathway
ngi04664  Fc epsilon RI signaling pathway
ngi04668  TNF signaling pathway
ngi04670  Leukocyte transendothelial migration
ngi04714  Thermogenesis
ngi04722  Neurotrophin signaling pathway
ngi04723  Retrograde endocannabinoid signaling
ngi04728  Dopaminergic synapse
ngi04750  Inflammatory mediator regulation of TRP channels
ngi04912  GnRH signaling pathway
ngi04914  Progesterone-mediated oocyte maturation
ngi04917  Prolactin signaling pathway
ngi04926  Relaxin signaling pathway
ngi04932  Non-alcoholic fatty liver disease
ngi04933  AGE-RAGE signaling pathway in diabetic complications
ngi04935  Growth hormone synthesis, secretion and action
ngi04936  Alcoholic liver disease
ngi05014  Amyotrophic lateral sclerosis
ngi05020  Prion disease
ngi05022  Pathways of neurodegeneration - multiple diseases
ngi05132  Salmonella infection
ngi05133  Pertussis
ngi05135  Yersinia infection
ngi05140  Leishmaniasis
ngi05142  Chagas disease
ngi05145  Toxoplasmosis
ngi05152  Tuberculosis
ngi05161  Hepatitis B
ngi05163  Human cytomegalovirus infection
ngi05167  Kaposi sarcoma-associated herpesvirus infection
ngi05169  Epstein-Barr virus infection
ngi05170  Human immunodeficiency virus 1 infection
ngi05171  Coronavirus disease - COVID-19
ngi05205  Proteoglycans in cancer
ngi05208  Chemical carcinogenesis - reactive oxygen species
ngi05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
ngi05415  Diabetic cardiomyopathy
ngi05417  Lipid and atherosclerosis
ngi05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ngi00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    103739659 (Mapk13)
   04015 Rap1 signaling pathway
    103739659 (Mapk13)
   04370 VEGF signaling pathway
    103739659 (Mapk13)
   04668 TNF signaling pathway
    103739659 (Mapk13)
   04068 FoxO signaling pathway
    103739659 (Mapk13)
   04071 Sphingolipid signaling pathway
    103739659 (Mapk13)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    103739659 (Mapk13)
  09143 Cell growth and death
   04114 Oocyte meiosis
    103739659 (Mapk13)
   04218 Cellular senescence
    103739659 (Mapk13)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    103739659 (Mapk13)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    103739659 (Mapk13)
   04613 Neutrophil extracellular trap formation
    103739659 (Mapk13)
   04620 Toll-like receptor signaling pathway
    103739659 (Mapk13)
   04621 NOD-like receptor signaling pathway
    103739659 (Mapk13)
   04622 RIG-I-like receptor signaling pathway
    103739659 (Mapk13)
   04625 C-type lectin receptor signaling pathway
    103739659 (Mapk13)
   04660 T cell receptor signaling pathway
    103739659 (Mapk13)
   04658 Th1 and Th2 cell differentiation
    103739659 (Mapk13)
   04659 Th17 cell differentiation
    103739659 (Mapk13)
   04657 IL-17 signaling pathway
    103739659 (Mapk13)
   04664 Fc epsilon RI signaling pathway
    103739659 (Mapk13)
   04670 Leukocyte transendothelial migration
    103739659 (Mapk13)
  09152 Endocrine system
   04912 GnRH signaling pathway
    103739659 (Mapk13)
   04914 Progesterone-mediated oocyte maturation
    103739659 (Mapk13)
   04917 Prolactin signaling pathway
    103739659 (Mapk13)
   04926 Relaxin signaling pathway
    103739659 (Mapk13)
   04935 Growth hormone synthesis, secretion and action
    103739659 (Mapk13)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    103739659 (Mapk13)
  09156 Nervous system
   04728 Dopaminergic synapse
    103739659 (Mapk13)
   04723 Retrograde endocannabinoid signaling
    103739659 (Mapk13)
   04722 Neurotrophin signaling pathway
    103739659 (Mapk13)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    103739659 (Mapk13)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    103739659 (Mapk13)
  09159 Environmental adaptation
   04714 Thermogenesis
    103739659 (Mapk13)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    103739659 (Mapk13)
   05208 Chemical carcinogenesis - reactive oxygen species
    103739659 (Mapk13)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    103739659 (Mapk13)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    103739659 (Mapk13)
   05161 Hepatitis B
    103739659 (Mapk13)
   05171 Coronavirus disease - COVID-19
    103739659 (Mapk13)
   05163 Human cytomegalovirus infection
    103739659 (Mapk13)
   05167 Kaposi sarcoma-associated herpesvirus infection
    103739659 (Mapk13)
   05169 Epstein-Barr virus infection
    103739659 (Mapk13)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    103739659 (Mapk13)
   05135 Yersinia infection
    103739659 (Mapk13)
   05133 Pertussis
    103739659 (Mapk13)
   05152 Tuberculosis
    103739659 (Mapk13)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    103739659 (Mapk13)
   05140 Leishmaniasis
    103739659 (Mapk13)
   05142 Chagas disease
    103739659 (Mapk13)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    103739659 (Mapk13)
   05020 Prion disease
    103739659 (Mapk13)
   05022 Pathways of neurodegeneration - multiple diseases
    103739659 (Mapk13)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    103739659 (Mapk13)
   05418 Fluid shear stress and atherosclerosis
    103739659 (Mapk13)
   05415 Diabetic cardiomyopathy
    103739659 (Mapk13)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    103739659 (Mapk13)
   04932 Non-alcoholic fatty liver disease
    103739659 (Mapk13)
   04933 AGE-RAGE signaling pathway in diabetic complications
    103739659 (Mapk13)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    103739659 (Mapk13)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ngi01001]
    103739659 (Mapk13)
Enzymes [BR:ngi01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     103739659 (Mapk13)
Protein kinases [BR:ngi01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   103739659 (Mapk13)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 APH Kdo Kinase-like
Other DBs
NCBI-GeneID: 103739659
NCBI-ProteinID: XP_008838307
UniProt: A0A8C6WBU4
LinkDB
Position
Un
AA seq 366 aa
MSLSRKKGFYKQDVNKTAWELPKTYLAPTHVGSGAYGAVCSAIDKRSGEKVAIKKLSRPF
QSEIFAKRAYRELLLLKHMHHENVIGLLDVFTSASSLRNFHDFYLVMPFMQTDLQKIMGM
EFSEDKVQYLVYQMLKGLKYIHSAGVVHRDLKPGNLAVNEDCELKILDFGLARHADAEMT
GYVVTRWYRAPEVILSWMHYNQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILKVTG
VPGTEFVQKLNDKAAKSYIQSLPQSPKKDFTQLFPRASPQAADLLDKMLELDVDKRLTAT
QALAHPFFEPFRDPEEETEAQQPFDDALEHEKLTVDEWKQHIYKEIMSFSPIARKDSRRR
CGMKLP
NT seq 1101 nt   +upstreamnt  +downstreamnt
atgagcctcagccggaaaaagggcttctacaagcaggacgtgaacaagacggcctgggag
ctgcccaagacctacctggcccccacgcacgtaggcagcggtgcctacggcgcagtatgc
tcggccattgacaagcggtcaggggagaaagtggccatcaagaagctaagccgacccttc
cagtcggagattttcgccaaacgtgcctatcgtgagctcctgctgctcaaacacatgcac
catgaaaatgtcattggactcctggatgtcttcacctctgcttcctccctgcgcaacttc
cacgatttctacctggtgatgcccttcatgcagacagatcttcagaagatcatggggatg
gagttcagtgaggataaggtccagtacctggtataccagatgctcaaaggtctaaagtac
atccactcagctggcgttgtccacagggacctgaagccaggcaacctggcagtgaatgag
gactgtgaactgaagatcctggattttgggctggcacgccatgcggatgcggagatgact
ggctatgtggtaacccgctggtaccgtgctcctgaagttattctcagctggatgcattac
aaccagactgtggacatctggtctgtcggctgcatcatggcagagatgcttacgggaaag
actctattcaagggaaaggattacctggaccagctgacccagattctgaaggtgactggg
gtgcctggcacagagtttgtgcagaaactcaacgacaaggcggccaaatcctacatccag
tccctgccccagagccccaagaaggatttcactcagctcttcccaagggccagtccccag
gctgctgacctcctggataagatgttggagctggatgtggacaagcgcctgacagccacg
caagcactcgcccaccccttctttgaacccttccgagaccctgaggaggagaccgaggcc
cagcagccattcgatgatgctctggaacacgagaaactcactgtggatgaatggaagcag
cacatctacaaagagatcatgagcttcagtcccatcgcccggaaggactctcggcgacgg
tgtggcatgaagctaccttga

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