Nannospalax galili (Upper Galilee mountains blind mole rat): 103741338
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Entry
103741338 CDS
T03372
Symbol
Prkaa1
Name
(RefSeq) protein kinase AMP-activated catalytic subunit alpha 1
KO
K07198
5'-AMP-activated protein kinase, catalytic alpha subunit [EC:
2.7.11.31
]
Organism
ngi
Nannospalax galili (Upper Galilee mountains blind mole rat)
Pathway
ngi04068
FoxO signaling pathway
ngi04140
Autophagy - animal
ngi04150
mTOR signaling pathway
ngi04151
PI3K-Akt signaling pathway
ngi04152
AMPK signaling pathway
ngi04211
Longevity regulating pathway
ngi04213
Longevity regulating pathway - multiple species
ngi04371
Apelin signaling pathway
ngi04530
Tight junction
ngi04710
Circadian rhythm
ngi04714
Thermogenesis
ngi04910
Insulin signaling pathway
ngi04920
Adipocytokine signaling pathway
ngi04921
Oxytocin signaling pathway
ngi04922
Glucagon signaling pathway
ngi04931
Insulin resistance
ngi04932
Non-alcoholic fatty liver disease
ngi04936
Alcoholic liver disease
ngi05410
Hypertrophic cardiomyopathy
ngi05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
ngi00001
]
09130 Environmental Information Processing
09132 Signal transduction
04371 Apelin signaling pathway
103741338 (Prkaa1)
04068 FoxO signaling pathway
103741338 (Prkaa1)
04151 PI3K-Akt signaling pathway
103741338 (Prkaa1)
04152 AMPK signaling pathway
103741338 (Prkaa1)
04150 mTOR signaling pathway
103741338 (Prkaa1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
103741338 (Prkaa1)
09144 Cellular community - eukaryotes
04530 Tight junction
103741338 (Prkaa1)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
103741338 (Prkaa1)
04922 Glucagon signaling pathway
103741338 (Prkaa1)
04920 Adipocytokine signaling pathway
103741338 (Prkaa1)
04921 Oxytocin signaling pathway
103741338 (Prkaa1)
09149 Aging
04211 Longevity regulating pathway
103741338 (Prkaa1)
04213 Longevity regulating pathway - multiple species
103741338 (Prkaa1)
09159 Environmental adaptation
04710 Circadian rhythm
103741338 (Prkaa1)
04714 Thermogenesis
103741338 (Prkaa1)
09160 Human Diseases
09166 Cardiovascular disease
05418 Fluid shear stress and atherosclerosis
103741338 (Prkaa1)
05410 Hypertrophic cardiomyopathy
103741338 (Prkaa1)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
103741338 (Prkaa1)
04932 Non-alcoholic fatty liver disease
103741338 (Prkaa1)
04931 Insulin resistance
103741338 (Prkaa1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ngi01001
]
103741338 (Prkaa1)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
ngi04131
]
103741338 (Prkaa1)
03029 Mitochondrial biogenesis [BR:
ngi03029
]
103741338 (Prkaa1)
Enzymes [BR:
ngi01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.31 [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase
103741338 (Prkaa1)
Protein kinases [BR:
ngi01001
]
Serine/threonine kinases: CAMK group
CAMKL family
103741338 (Prkaa1)
Membrane trafficking [BR:
ngi04131
]
Autophagy
Other autophagy associated proteins
Others
103741338 (Prkaa1)
Mitochondrial biogenesis [BR:
ngi03029
]
Mitochondrial quality control factors
Regulator of mitochondrial biogenesis
Other regulator of mitochondrial biogenesis
103741338 (Prkaa1)
Mitophagy factors
Other mitophagy factors
103741338 (Prkaa1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
AMPK_alpha_AID
AdenylateSensor
ABC1
Kinase-like
Kdo
APH
Motif
Other DBs
NCBI-GeneID:
103741338
NCBI-ProteinID:
XP_008840319
UniProt:
A0A8C6QP32
LinkDB
All DBs
Position
Un
AA seq
558 aa
AA seq
DB search
MRRLSSWRKMATAEKQKHDGRVKIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNR
QKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNG
RLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEF
LRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDG
IFYTPQYLNPSVISLLKHMLQVDPMKRATIKDIREHEWFKQDLPKYLFPEDPSYSSTMID
DEALKEVCEKFECAEEEVLSCLYNRNHQDPLAVAYHLIIDNRRIMNEAKDFYLATSPPDS
FLDDHHLTRPHPERVPFLVAETPRARHTLDELNPQKSKHQGVRKAKWHLGIRSQSRPNDI
MAEVCRAIKQLDYEWKVVNPYYLRVRRKNPVTSTFSKMSLQLYQVDSRTYLLDFRSIDDE
ITEAKSGTATPQRSGSISNYRSCQRSDSDAEAQGKSSEVSLTSSVTSLDTSVDLAPRPGS
HTIEFFEMCANLIKILAQ
NT seq
1677 nt
NT seq
+upstream
nt +downstream
nt
atgcgcagactcagttcctggagaaagatggcgacggccgagaagcagaagcacgacggg
cgggtgaagatcggccactacatcctgggggacacgctgggcgtcggcaccttcgggaaa
gtgaaggttggcaaacatgaattgaccgggcataaagttgctgtgaaaatactcaatcgg
cagaagattcgaagtcttgacgtggttggaaaaatccgcagagaaattcagaacctcaag
cttttcaggcatcctcatataattaaactgtaccaggtcatcagtacaccatctgatatt
ttcatggtgatggaatatgtctcaggaggagagctatttgattatatctgtaaaaatgga
aggctggatgaaaaagaaagtcgacgtctgttccaacagatcctttctggtgtggattat
tgtcacaggcatatggtagtccacagagatttgaaacctgaaaatgtcctgcttgatgca
cacatgaatgcaaagatagctgattttggtctttcaaacatgatgtcagatggtgaattt
ttaagaacaagttgtggctcaccgaactatgctgcaccagaagtgatctcaggaagattg
tacgcaggcccggaggtggacatctggagcagcggggtcattctctatgctttgctgtgt
gggacccttccctttgatgatgaccacgtgccaactctttttaagaagatatgcgatggg
attttttatacccctcagtatttgaatccttctgtgatcagccttttgaagcatatgctg
caggtagatcccatgaagagggccacaatcaaagacatcagggaacatgaatggtttaaa
caggaccttccaaaatacctctttcctgaagatccatcctatagttcaaccatgattgat
gatgaagccttaaaagaagtgtgtgagaagtttgaatgcgcagaagaggaggtgctcagc
tgcctgtataataggaatcaccaggacccattggcagttgcctaccatctcataatagac
aacaggagaataatgaatgaagccaaagatttctacttggcaacaagcccacctgattct
ttccttgatgatcaccatttaactcgaccccatcctgaaagagtaccattcttggtggct
gaaacaccaagggcacggcataccctcgatgaattaaacccacagaaatccaaacaccaa
ggtgtacggaaagcaaaatggcatttgggaattagaagtcaaagtcgaccaaatgatatc
atggcagaagtatgcagagcgatcaagcagttggactatgaatggaaggttgtaaaccca
tattatttgcgtgtgcgaaggaagaatcctgtgacaagcacattttccaaaatgagtcta
cagttgtaccaagtggatagcaggacttacttactggatttccgaagcattgatgatgaa
attacagaggccaaatcagggactgctactccacagagatcgggatccatcagcaactat
cgctcttgccaaaggagtgactccgatgctgaagctcaagggaagtcctcagaagtttct
cttacctcgtctgtgacctcacttgacacttctgttgacttagctccaagacctggaagt
cacacaatagaattttttgaaatgtgtgcaaatctaattaaaattcttgcacaataa
DBGET
integrated database retrieval system
