Nannospalax galili (Upper Galilee mountains blind mole rat): 103743944
Help
Entry
103743944 CDS
T03372
Symbol
Sos1
Name
(RefSeq) SOS Ras/Rac guanine nucleotide exchange factor 1
KO
K03099
son of sevenless
Organism
ngi
Nannospalax galili (Upper Galilee mountains blind mole rat)
Pathway
ngi01521
EGFR tyrosine kinase inhibitor resistance
ngi01522
Endocrine resistance
ngi04010
MAPK signaling pathway
ngi04012
ErbB signaling pathway
ngi04014
Ras signaling pathway
ngi04062
Chemokine signaling pathway
ngi04068
FoxO signaling pathway
ngi04072
Phospholipase D signaling pathway
ngi04150
mTOR signaling pathway
ngi04151
PI3K-Akt signaling pathway
ngi04510
Focal adhesion
ngi04540
Gap junction
ngi04630
JAK-STAT signaling pathway
ngi04650
Natural killer cell mediated cytotoxicity
ngi04660
T cell receptor signaling pathway
ngi04662
B cell receptor signaling pathway
ngi04664
Fc epsilon RI signaling pathway
ngi04714
Thermogenesis
ngi04722
Neurotrophin signaling pathway
ngi04810
Regulation of actin cytoskeleton
ngi04910
Insulin signaling pathway
ngi04912
GnRH signaling pathway
ngi04915
Estrogen signaling pathway
ngi04917
Prolactin signaling pathway
ngi04926
Relaxin signaling pathway
ngi04935
Growth hormone synthesis, secretion and action
ngi05034
Alcoholism
ngi05160
Hepatitis C
ngi05161
Hepatitis B
ngi05163
Human cytomegalovirus infection
ngi05165
Human papillomavirus infection
ngi05200
Pathways in cancer
ngi05205
Proteoglycans in cancer
ngi05206
MicroRNAs in cancer
ngi05207
Chemical carcinogenesis - receptor activation
ngi05208
Chemical carcinogenesis - reactive oxygen species
ngi05210
Colorectal cancer
ngi05211
Renal cell carcinoma
ngi05213
Endometrial cancer
ngi05214
Glioma
ngi05215
Prostate cancer
ngi05220
Chronic myeloid leukemia
ngi05221
Acute myeloid leukemia
ngi05223
Non-small cell lung cancer
ngi05224
Breast cancer
ngi05225
Hepatocellular carcinoma
ngi05226
Gastric cancer
ngi05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
ngi00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
103743944 (Sos1)
04012 ErbB signaling pathway
103743944 (Sos1)
04014 Ras signaling pathway
103743944 (Sos1)
04630 JAK-STAT signaling pathway
103743944 (Sos1)
04068 FoxO signaling pathway
103743944 (Sos1)
04072 Phospholipase D signaling pathway
103743944 (Sos1)
04151 PI3K-Akt signaling pathway
103743944 (Sos1)
04150 mTOR signaling pathway
103743944 (Sos1)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
103743944 (Sos1)
04540 Gap junction
103743944 (Sos1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
103743944 (Sos1)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
103743944 (Sos1)
04660 T cell receptor signaling pathway
103743944 (Sos1)
04662 B cell receptor signaling pathway
103743944 (Sos1)
04664 Fc epsilon RI signaling pathway
103743944 (Sos1)
04062 Chemokine signaling pathway
103743944 (Sos1)
09152 Endocrine system
04910 Insulin signaling pathway
103743944 (Sos1)
04912 GnRH signaling pathway
103743944 (Sos1)
04915 Estrogen signaling pathway
103743944 (Sos1)
04917 Prolactin signaling pathway
103743944 (Sos1)
04926 Relaxin signaling pathway
103743944 (Sos1)
04935 Growth hormone synthesis, secretion and action
103743944 (Sos1)
09156 Nervous system
04722 Neurotrophin signaling pathway
103743944 (Sos1)
09159 Environmental adaptation
04714 Thermogenesis
103743944 (Sos1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
103743944 (Sos1)
05206 MicroRNAs in cancer
103743944 (Sos1)
05205 Proteoglycans in cancer
103743944 (Sos1)
05207 Chemical carcinogenesis - receptor activation
103743944 (Sos1)
05208 Chemical carcinogenesis - reactive oxygen species
103743944 (Sos1)
05231 Choline metabolism in cancer
103743944 (Sos1)
09162 Cancer: specific types
05210 Colorectal cancer
103743944 (Sos1)
05225 Hepatocellular carcinoma
103743944 (Sos1)
05226 Gastric cancer
103743944 (Sos1)
05214 Glioma
103743944 (Sos1)
05221 Acute myeloid leukemia
103743944 (Sos1)
05220 Chronic myeloid leukemia
103743944 (Sos1)
05211 Renal cell carcinoma
103743944 (Sos1)
05215 Prostate cancer
103743944 (Sos1)
05213 Endometrial cancer
103743944 (Sos1)
05224 Breast cancer
103743944 (Sos1)
05223 Non-small cell lung cancer
103743944 (Sos1)
09172 Infectious disease: viral
05161 Hepatitis B
103743944 (Sos1)
05160 Hepatitis C
103743944 (Sos1)
05163 Human cytomegalovirus infection
103743944 (Sos1)
05165 Human papillomavirus infection
103743944 (Sos1)
09165 Substance dependence
05034 Alcoholism
103743944 (Sos1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
103743944 (Sos1)
01522 Endocrine resistance
103743944 (Sos1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
RasGEF
RasGEF_N
RhoGEF
SOS1_NGEF_PH
PH
PH_10
PH_19
IQ_SEC7_PH
RHG20_PH
Takusan
Motif
Other DBs
NCBI-GeneID:
103743944
NCBI-ProteinID:
XP_008843731
LinkDB
All DBs
Position
Un
AA seq
1334 aa
AA seq
DB search
MQAQQLPYEFFSEENAPKWRGLLVPALKKVQGQVHPTLESNDDALQYVEELILQLLNMLC
QAQPRSASDVEERVQKSFPHPIDKWAIADAQSAIEKRKRRNPLSLPVEKIHPLLKEVLGY
KIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHYEITKQDIKVAMCADKVLMDMFHQDV
EDINILSLTDEEPSTSGEQTYYDLVKAFMAEIRQYIRELNLIIKVFREPFVSNSKLFSSY
DVENIFSRIVDIHELSIKLLGHIEDTVEMTDEGSPHPLVGSCFEDLAEELAFDPYESYAR
DILRPGFHDRFLSQLSKPGAALYLQSIGEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQL
EEKSEDQEDKECLKQAITALLNVQSGMEKICSKSLAKRRLSESACRFYSQQMKGKQLAIK
KMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQPRL
PGASNAEYRLKEKFFMRKVQINDKDDTSEYKHAFEIILKDENSVIFSAKSAEEKNNWMAA
LISLQYRSTLERMLDVTMLQEEKEEQMRLPSADVYRFAEPDSEENIIFEENMQPKAGIPI
IKAGTVVKLIERLTYHMYADPNFVRTFLTTYRSFCKPQEIQFLMLEKFEIPEPEPTEADR
IAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDADLLQRMEEFIGT
VRGKAMKKWVESITKIIQRKKIARDNGPGHNITFQSSPPTVEWHISRPGHIETFDLLTLH
PIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIV
ETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKI
LEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLKRHGKELINFSK
RRKVAEITGEIQQYQNQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRN
PKPLPRFPKKYSYPLKSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETESTASAP
NSPRTPLTPPPASGASSTTDVCSVFDSDHSTSPFHSSSDTVFIQVTLPHGPRSASVSSIS
LTKGTDEVPVPPPVPPRRRPESAPVESSPSKIMPKHLDSPPAIPPRQPTSKAYSPRYSVS
DRTSISDPPESPPLLPPREPVRTPDVFSSSPLHLQPPPLGKKSDHGNAFFPNSPSPFTPP
PPQTPSPHGTRRHLPSPPLTQEVDLHSIAGPPVPPRQSTSQHIPKLPPKTYKREHTHPSM
HRDGPPLLENAHSS
NT seq
4005 nt
NT seq
+upstream
nt +downstream
nt
atgcaggcgcagcagctgccctacgagtttttcagcgaggagaatgcacccaagtggcgg
gggctgctggtgccggcgctgaaaaaggttcaggggcaagttcatcctactcttgagtct
aatgatgatgctcttcagtatgttgaagaattaattttgcagttattaaatatgctctgc
caagctcagccccggagtgcttcagatgtagaggaacgtgttcaaaaaagtttccctcat
ccaattgataagtgggcaatagctgatgcccaatcggctattgaaaagaggaagagaaga
aaccctttatctctcccagtagaaaaaattcatcctttattaaaggaggtcctaggttat
aaaatcgaccaccaggtttctgtttacatagtagcagtattagaatatatttctgctgat
attttaaagctggtggggaattatgtaagaaatatacggcattatgaaattacgaaacaa
gatattaaagtggcaatgtgtgctgataaggtattgatggatatgtttcatcaagatgta
gaagatataaatatattatctttaactgatgaagagccttccacctcaggagaacaaact
tactatgatttggtaaaagcatttatggcagaaattcgacaatatataagagaactaaac
ctaattataaaagtttttagagagccctttgtctctaattccaaattgttttcatcttat
gatgtagaaaacatatttagtcgtatagtggatatacatgaacttagtataaagttactg
ggccatatagaagacactgtagaaatgacagatgaaggcagtccccatccattagtagga
agctgttttgaagacttagcagaggaactggcatttgacccatatgaatcatatgctcga
gatattttacgaccaggatttcatgaccgtttccttagtcagttatcaaagcctggggca
gcactttatttgcagtcaataggggaaggtttcaaagaagctgttcagtatgttttaccc
cggctgcttcttgcccctgtgtaccactgtctgcattactttgaactcctgaagcagtta
gaagaaaagagtgaagatcaagaagacaaggaatgtttgaaacaagcaataacagctttg
ctcaatgttcaaagtggtatggaaaaaatatgttctaaaagccttgcaaaacgaagactg
agtgaatctgcatgtcggttttatagccaacaaatgaaggggaaacaactagcgatcaag
aaaatgaacgagattcagaagaatattgatggttgggaagggaaagacattggacagtgt
tgcaatgaatttataatggaaggaactcttacacgtgtaggagccaaacatgagagacac
atatttctctttgatggcttaatgatctgctgtaaatcaaatcatggacagccaagacta
cctggtgctagcaatgcagaatatcgtctgaaagaaaagttttttatgcgaaaggtacaa
attaatgataaagatgacaccagtgaatacaagcatgcttttgaaataattctgaaagat
gaaaatagtgttatattttctgccaagtcagctgaagagaaaaacaactggatggcagca
ttgatatctttacagtaccggagtacactggaaagaatgcttgatgtaacaatgctacag
gaagagaaggaggagcagatgaggctgcctagtgctgatgtatataggtttgcagaacct
gactctgaggagaatattatatttgaagagaacatgcagcccaaggctggaattccaatc
atcaaagcaggaactgttgttaaacttatagagagacttacataccatatgtatgcagat
cccaattttgttcggacatttcttacaacatacagatccttttgtaaacctcaagaaatt
cagtttttgatgcttgaaaaatttgaaataccagagcctgagccaacagaagctgatcgc
atagctatagagaatggagatcagcccctaagtgcagaactgaaaaggtttagaaaagaa
tatatacagcctgtacaactgagagtgttaaatgtatgccggcactgggtggagcaccac
ttttatgattttgaaagagatgcagatcttttacaaagaatggaagaatttattggaaca
gtaagaggtaaagcaatgaaaaaatgggttgaatccatcactaagataatccaaaggaaa
aaaattgcaagagacaatggaccaggtcataatattacatttcaaagttcacctcccaca
gttgagtggcacataagcagacctgggcatatagagacttttgacttgctcaccttacac
ccaatagaaattgctcgacagcttactttacttgaatctgatctataccgagctgtgcag
ccatcagaattagttggaagtgtgtggacaaaagaagacaaagaaattaattctcccaat
cttctgaaaatgatacgacacaccaccaatcttactctgtggtttgaaaaatgtattgta
gaaactgaaaatttagaagaaagagtagctgtggtgagtcgaataattgagattctacaa
gtctttcaagagttgaacaatttcaatggtgtccttgaagttgtcagtgctatgaactca
tcacctgtttacaggctagaccacacatttgagcaaataccaagtagacaaaagaaaatt
ttagaagaagctcatgaattgagtgaagatcactataagaaatatttggcaaaactcagg
tctattaatccaccgtgtgtgcctttctttggaatttatctcactaatatcttgaaaaca
gaagaaggcaaccctgaagtcctaaaaagacatggaaaagaacttatcaactttagcaaa
agaaggaaagtggcagaaataacaggagagatccagcagtaccaaaatcagccttactgt
ttacgagtagaatcagacatcaaaaggttctttgaaaacttgaatccaatgggaaatagc
atggagaaagaatttacagactaccttttcaacaaatccctagaaatagaaccacgaaac
cctaagcctctcccaagatttccaaaaaaatacagctatcccctaaaatctcctggtgtt
cgtccatcgaacccaagaccaggaactatgaggcaccccacacctctgcagcaggagcca
agaaaaatcagttatagtcggatccctgaaagtgaaacagaaagtacagcatccgcacca
aattctccgagaacaccgctgacacctcctcctgcttctggtgcttccagtaccacagat
gtttgcagtgtgtttgattccgaccattcaacaagcccttttcactcaagcagcgatacc
gtctttatccaagttacactgccccatggtccaagatctgcttcagtatcatctataagt
ttgaccaaaggcactgatgaagtgcctgtcccccctcctgttcctcctcgaagacgacca
gaatctgccccagtggaatcttcgccatctaagattatgcctaagcacttggacagtccc
ccagctattcctcccaggcaacccacatcaaaagcctattcaccacgatattcagtatca
gaccggacctctatatcagaccctcctgaaagccctcccttgttgccaccacgagaacct
gtgaggacacctgatgttttctcaagctcaccactacatctccaacctccccctttgggc
aaaaagagtgaccatggcaatgccttcttcccaaacagcccttccccctttacaccacca
cctcctcaaaccccttctcctcatggcacaagaaggcacctgccatcaccaccactgaca
caagaagtggacctccattccattgctgggccacctgttcctccacgacaaagcacttct
cagcatatccctaaactccctccaaaaacttacaaaagggagcacacgcatccatccatg
cacagagatggaccaccactgttggagaatgcccactcttcctga
DBGET
integrated database retrieval system
