Nannospalax galili (Upper Galilee mountains blind mole rat): 103745419
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Entry
103745419 CDS
T03372
Symbol
Syk
Name
(RefSeq) spleen associated tyrosine kinase
KO
K05855
spleen tyrosine kinase [EC:
2.7.10.2
]
Organism
ngi
Nannospalax galili (Upper Galilee mountains blind mole rat)
Pathway
ngi04064
NF-kappa B signaling pathway
ngi04072
Phospholipase D signaling pathway
ngi04151
PI3K-Akt signaling pathway
ngi04380
Osteoclast differentiation
ngi04611
Platelet activation
ngi04613
Neutrophil extracellular trap formation
ngi04625
C-type lectin receptor signaling pathway
ngi04650
Natural killer cell mediated cytotoxicity
ngi04662
B cell receptor signaling pathway
ngi04664
Fc epsilon RI signaling pathway
ngi04666
Fc gamma R-mediated phagocytosis
ngi05152
Tuberculosis
ngi05167
Kaposi sarcoma-associated herpesvirus infection
ngi05168
Herpes simplex virus 1 infection
ngi05169
Epstein-Barr virus infection
ngi05171
Coronavirus disease - COVID-19
ngi05203
Viral carcinogenesis
Brite
KEGG Orthology (KO) [BR:
ngi00001
]
09130 Environmental Information Processing
09132 Signal transduction
04064 NF-kappa B signaling pathway
103745419 (Syk)
04072 Phospholipase D signaling pathway
103745419 (Syk)
04151 PI3K-Akt signaling pathway
103745419 (Syk)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
103745419 (Syk)
04613 Neutrophil extracellular trap formation
103745419 (Syk)
04625 C-type lectin receptor signaling pathway
103745419 (Syk)
04650 Natural killer cell mediated cytotoxicity
103745419 (Syk)
04662 B cell receptor signaling pathway
103745419 (Syk)
04664 Fc epsilon RI signaling pathway
103745419 (Syk)
04666 Fc gamma R-mediated phagocytosis
103745419 (Syk)
09158 Development and regeneration
04380 Osteoclast differentiation
103745419 (Syk)
09160 Human Diseases
09161 Cancer: overview
05203 Viral carcinogenesis
103745419 (Syk)
09172 Infectious disease: viral
05171 Coronavirus disease - COVID-19
103745419 (Syk)
05168 Herpes simplex virus 1 infection
103745419 (Syk)
05167 Kaposi sarcoma-associated herpesvirus infection
103745419 (Syk)
05169 Epstein-Barr virus infection
103745419 (Syk)
09171 Infectious disease: bacterial
05152 Tuberculosis
103745419 (Syk)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ngi01001
]
103745419 (Syk)
Enzymes [BR:
ngi01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
103745419 (Syk)
Protein kinases [BR:
ngi01001
]
Non-receptor tyrosine kinases
SYK family
103745419 (Syk)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
SH2
DUF7145
DUF7063
Kdo
ABC1
SH2_1
RIO1
Motif
Other DBs
NCBI-GeneID:
103745419
NCBI-ProteinID:
XP_008845574
LinkDB
All DBs
Position
Un
AA seq
629 aa
AA seq
DB search
MAGNTADSANHLPYFFGNITREEAEDYLVQGGMTDGLYLLRQSRNYLGGFALSVAHNRKA
HHYTIERELNGTYAISGGRTHASPADLCQYHSQESDGLVCLLKKPLNRPPGVQPKTGPFE
DLKENLIREYVKQTWNLQGQALEQAIISQKPQLEKLIATTAHEKMPWFHGNISRDESEQT
VLIGSKINGKFLIRARDNSGSYALCVLHEGKVLHYRIDKDKTGKLSIPEGKKFDTLWQLV
EHYSYKPDGLLRVLTVPCQKIGAQTGNSQNSSAHPVTWSAGGIISRIKSYTFPKPGHRKT
APTPASRPESTVSFNPYEPSGGPWSPDRGLQREALPMDTEVYESPYADPEEIRPKEVYLD
RSLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNETNDPALKDELLAEANVMQQ
LDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNKHVKDKNIIELVHQVSMGMKYLE
ECNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINY
YKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPQGCPREMYELMN
LCWTYEVENRPGFTAVELRLRNYYYDVVN
NT seq
1890 nt
NT seq
+upstream
nt +downstream
nt
atggcgggcaacacggctgacagcgccaaccacctgccctactttttcggcaacatcact
cgggaggaggctgaagactacctggtccagggaggaatgacagatgggctctacctgctg
cgccagagccgcaattacctgggcggatttgccctgtccgtggcccacaacaggaaggca
caccactacaccattgagagggagctcaatggcacctatgctatctctggtggcaggacc
catgccagtcctgccgacctctgccaataccactcccaggaatccgatggcctcgtctgc
ctcctcaagaagcccttaaatcggcccccaggggtgcagcccaagaccgggccttttgag
gacctgaaagaaaacctcatcagggaatatgtgaagcagacctggaacctgcagggccag
gctctggagcaagccatcatcagccagaagccccagctggagaagctgatcgccaccact
gcccatgagaagatgccctggttccatggcaacatctccagggatgaatcagagcagacc
gtcctcatagggtcaaagatcaatgggaaattcctaatcagggccagagacaacagtggc
tcctacgcactgtgcgtactacatgaagggaaggtgttgcactatcgcatcgacaaggat
aagacagggaagctctccatccctgaagggaagaagtttgacactctctggcagctggtg
gagcattactcttataagccagatgggctgttaagagtcctcacagtgccatgccaaaag
attggtgcacagacgggtaactcacagaattcaagtgcccaccctgtgacttggtcagcg
ggtggaataatctcaagaatcaaatcctacaccttcccaaagcccggccacagaaagact
gctccaactccagccagccgtccagagagcactgtgtcattcaacccctacgagccatca
ggagggccctggtccccagacagaggccttcagagagaagccctacccatggacacagag
gtgtacgagagcccctatgctgatcctgaggagatccggcccaaggaggtctacctagat
cgaagcctgctgaccctggaggacaaagaactgggctcgggtaacttcgggactgtgaaa
aagggctactaccaaatgaaaaaagtggtgaaaacagtggcggtgaagatcctgaagaat
gagaccaatgaccctgctctgaaggacgagctgctggcagaggcgaacgtcatgcagcag
ctggacaacccctacatcgtgcgcatgattgggatctgcgaggccgagtcttggatgctg
gtgatggagatggcagagctcggacccctcaacaagtacctgcaacagaacaagcacgtc
aaggataagaacatcatagaactggtccaccaggtttccatggggatgaagtatttggag
gagtgcaactttgtgcacagagatctggctgcgaggaacgtgctgctggtcactcagcat
tatgccaagatcagtgattttggtctttccaaagctcttcgtgctgatgaaaactactac
aaggcccagacccacgggaagtggcccgtgaagtggtacgcccctgaatgcatcaactac
tacaagttctccagtaagagcgacgtgtggagcttcggagttctgatgtgggaggcgttc
tcctatgggcagaagccctatcgagggatgaaagggagcgaggttactgccatgctggag
aaaggagagcggatggggtgcccccaagggtgcccaagagagatgtatgagctgatgaac
ctgtgctggacatacgaggtggaaaacagaccgggattcacagcagtggagctgcggctg
cgcaattactattacgacgtggttaactaa
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