Nannospalax galili (Upper Galilee mountains blind mole rat): 103746842
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Entry
103746842 CDS
T03372
Symbol
Spg11
Name
(RefSeq) spastic paraplegia 11 (autosomal recessive)
KO
K19026
spatacsin
Organism
ngi
Nannospalax galili (Upper Galilee mountains blind mole rat)
Pathway
ngi04142
Lysosome
ngi05014
Amyotrophic lateral sclerosis
ngi05022
Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:
ngi00001
]
09140 Cellular Processes
09141 Transport and catabolism
04142 Lysosome
103746842 (Spg11)
09160 Human Diseases
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
103746842 (Spg11)
05022 Pathways of neurodegeneration - multiple diseases
103746842 (Spg11)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03400 DNA repair and recombination proteins [BR:
ngi03400
]
103746842 (Spg11)
DNA repair and recombination proteins [BR:
ngi03400
]
Eukaryotic type
DSBR (double strand breaks repair)
HR (homologous recombination)
Other HR factors
103746842 (Spg11)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Spatacsin_C
Motif
Other DBs
NCBI-GeneID:
103746842
NCBI-ProteinID:
XP_008847359
UniProt:
A0A8C6QNM9
LinkDB
All DBs
Position
Un
AA seq
2437 aa
AA seq
DB search
MAAKPGVGSAVSHGSAGATERVLSILLVPVATEASVQLGSRAQLHREQEALGSLTAGGSL
QVLSLAPGSRGGSSCSLDGPFGHFVWEESRNSSTSTDKPKLLAFSENYKLFMYEFNLKDG
RCDAALLYSCSGKTLEKLIEDQGISVSLQSLKILSFHDNTSLLFINRCIVLRVLFPERDA
EMRVLSCLTLSLPAQTVETIIDVQLCRGVLFVLSTLDWIYIFNTVNGMHVANVDLALLQE
DSCNEQQQESARTSSFTSLKVAQDLDVLVIVSNSSTAVALDLDLYFSQHPGHLLCERTPD
DLPIQGPVGIDEDDPLNSVHNMKLTKVSFQVDRSWKAQLSSLNETIKSSKLEVSYCAPWF
QGILHLESTESGNHVLRVLNRVFIPEDVLHGQCAFPQKEHIKTSDPRRSWKTMHLTEQEQ
PTELKCMSATGFTALFTWAMGTTSCTIVLWDLETQNLECLSLSQCIPVESSGDQQLCLVL
TENGLSLILFGLTQEEFLNRLMIHGSAGTVDTLCHLNGWGRCSIPIHALEAGIENRQLDT
VDFFLKSKENLLTPSSKSSVPDQFHSFSSLLYLKNVEEMTPALDLLCSAIRESDSETQSK
HFSEQLLNLTLSFLNKQIKELFVHTEELDEHLQKGVDILTSYINKLRTFMIKFPWKPADA
IGDYDVNENVSTVKESKIWEKLSFEEIIANAILNNKIPEAQTFFRITSHSAQRLEELIRM
GLDLVFNSLKKSNIKEASILLKNMGFDVKDQLLKICFYTTDKNTRDFLVEILKEKKYFSE
KEKRTIDFVHQVEKVYSGHFQENMQIQSFPRYWIKEQDFFKHESLLNTVLKYDHKDEFDQ
QDHRIALNWAHWWDQPTQDRILLPRTNPEEYKSYSPEALWSYLTAHHDRLSITLWIEEFQ
AQETMSLQQNKWPPLTVDVIDQNTCCNNYMRNEILDKLARCGIFLTSELEDFELFLQRLS
RIGGIIQDTLPVQNYKSKEGWDFHSRFILYCLEHNLQHLLYVYLDYYKLCPENSPFLEKK
ELYEAHPWFEFLVQCRQVSSNLTDPKLIFQASLANAQILIPTNQASVSSMLLEGHTLLAL
ATTVYAPGGISQVIQNKENESCLKKVDSQLLKMALTPYPKLKTALFPQYTAPSILPSDVT
LYHLIQSLSPFDPSRLFGWQSANTLAIGDASSHLPHFSSPDLVNKYAVMERLNFAYYLHH
GRPSFAFATFLVQELIKSKTPKQLIQQVGKEAYILGLSSFHIPSVGAACVCFLELLGLGS
LKLRVDMKVANTIFEYRCRNEDAQSSFIRDSLAEKLSRLANGDKAAMEELLVLLEEGTWN
SIQQQDIKRLSNESGSQWTLVVQFCTLHSMKLSMSYLRECARANDWLQFITHSQLHSYHP
EEVKSLLQYFSPVLQSHLKLAFENLPSVSSSRTDSEQVFTIPQELQKNEEMADFFEILHR
CSEESDSWLWLLAEAVKQQAPILSILASCLQGASAIPCLCVWIVTSVEDSIAAEAMGHIQ
VSIEDHTWDLGDLSIIWRTLLTKQKSSTLIQGFQLFFKDSPLLLMMEVYELCMFFKNYKK
ARAKLLEFQKSLGMLDIAATRVFPNIPAAWVKDQVCFLLKLMPQQCQTQYELGQLLQLFV
GVEHLFSDGPDMRKLCVLSQILKDTSITINHAVITSYSIENFQHECRSILEKLKIDGQFV
LARTVAELAELPVDSLVIEEIIQEMQTLKHIEQWSLKQARIDFWKKCHQNFKKNSISNKA
ASSFFSTQALVAREHPTGQSNIGERHLLLTLAGHWIAQEEPVPVQELEELEKQIWVCRIT
QHTLKGSQEEVEPRFSREISTSGELSFDSLASEFSFSKLASLNTSKYLELNGLPPKETCE
NRLDYKEQESLNVLIGHLLNDGCVHEASRVCQYFHFYNQDVALVLHCRALASGEASVDDL
HPDIRALLQSTKLPEEEESPSAPVRKVHSTSSLDSQSFVMVPPGDEMVRNLRTLTSRCLN
GKNYCRQILCLYELAKELGCSYADVAAGDGEVMLRAILSSQQPDRCKQAQAFISTQGLKP
DTVAELVAEEVTRELLTPSEGTGQKQIFNATEESQIFLQLTALCQDRTLVGMKLLDKISS
VPLGELSCTTELLILAHHCFTLTCHMEGIIRVLQAARMLTDNHLAPNEEYGLVVRLLTGI
GRYNEMTYIFDLLHKKHYFEVLMRKKLDPSGTLKTALLDYIKRCHPGDSEKHNMIALCFS
MCREIGENHEAAACIQLKLIESQPWEDSLKDGPHLKQLLLKALTLMLDAAESYAKDSCVR
QALHCNRLTKLITLQIHFLNSGQNTMLINLGHHKLMDCIMALPRFYQASIVAEAYDFVPD
WAEVLYQKVILKGDFNYLEEFKQQKLLQSNIFEEISRKYKQHQPTDRATENLKKLLSYCE
DIYLYYKLAYEHKFFEIVNVLLKDPQTGCCLKDMLAG
NT seq
7314 nt
NT seq
+upstream
nt +downstream
nt
atggctgctaagccgggggtcggaagtgctgtatcccacggctcagctggggccacggag
cgggttctgtcaatactactcgtgccggttgccaccgaagcgtctgtgcagctgggatcg
cgggcgcagctgcaccgggagcaggaggccctggggagcctgacggctgggggcagtctc
caagtgctttccttggcgccgggcagtcggggcggaagcagctgcagcctggacggcccc
tttgggcactttgtatgggaggagtctcgtaacagcagcacatcaacagacaagcccaag
ctgcttgcttttagtgaaaattataagctgtttatgtatgaatttaacttgaaagatgga
agatgtgatgcagccttattatacagctgtagtgggaagacactggaaaagctcattgaa
gatcaaggtattagtgtttccttacagtctttgaaaatcctctcctttcacgacaacaca
tcattattgttcatcaacagatgtatcgtcctacgagttctgtttcctgagagagatgct
gagatgagagtgctcagctgtttgacactgtccttgcccgcacaaacagtggaaacgatt
atcgatgtgcagctctgcagaggagttctttttgtgctgagtacattagactggatctat
atttttaacactgtgaatggcatgcatgtagctaatgtagacttagcacttctccaagaa
gattcttgtaatgagcaacagcaggaatcagccaggacttcgtcctttacgtcattgaaa
gtggctcaagacttggatgtgttggtgattgtcagcaactccagcactgcagttgctctt
gacctagatttgtatttcagccaacacccaggacatctgctttgtgaaagaacaccagac
gaccttcctattcaaggaccagtggggatagatgaagatgatcctcttaactctgtccac
aacatgaaactgaccaaggtttcctttcaagttgataggtcttggaaggcccagctttca
tcactgaatgaaacaataaagagctctaaactggaggtttcctattgtgctccatggttc
cagggtattttgcatttggagtccactgaatctggtaaccatgttctcagggtgctaaac
cgggtttttattccagaggatgtgctgcatggccagtgtgcttttccacagaaagagcac
atcaagaccagtgatccaagaagatcatggaagacaatgcacctcactgaacaagagcaa
cccacagagcttaagtgtatgtctgcaacaggatttactgcactgtttacttgggccatg
ggaacaactagctgtaccattgtcctctgggatttggagactcagaacttggagtgtttg
tctctcagccagtgcattcctgtagagagtagtggagaccagcagctgtgcctcgttctg
acagaaaatgggctctctctgattttgtttggtttaactcaagaggagtttttaaacaga
ctaatgatccatggaagtgcgggcactgtggacaccctttgtcatctcaatggctgggga
cggtgttcaattcctattcacgctctagaggcagggatagaaaatcgccagctagataca
gtggatttcttcttgaagagcaaggaaaatcttcttactccatcttcaaaatcttctgtg
cctgatcagttccattcattttcatcccttttatacttaaaaaatgtagaagaaatgaca
ccagcattggatttactttgttcagcaattagagaaagtgactctgaaacccaaagcaaa
cacttttcagaacagttgcttaatcttacactgtctttccttaacaaacaaataaaggaa
ctttttgttcacactgaagagttagatgaacatctacagaaaggagtggacattttgacc
agctacattaataaacttcgaacttttatgataaaatttccttggaagccagcagatgct
ataggtgactatgatgtaaatgaaaatgtctccacagtaaaggagagtaaaatatgggag
aaactcagctttgaggaaattattgccaatgccattttaaataacaaaataccagaggca
caaactttcttcaggattaccagtcattcagctcaaagactagaggaattgattaggatg
ggcctagatttggtcttcaacagtttaaagaagagcaatataaaagaagcctccatactt
ttgaagaatatgggttttgatgtgaaagatcagttactcaagatatgcttctatacaact
gacaaaaatacacgggactttttggttgaaattttaaaagaaaaaaagtatttttctgaa
aaagaaaaaagaactatagactttgttcatcaagttgagaaggtttattcaggacatttc
caagaaaatatgcagatccagtcctttcccaggtattggataaaggaacaagattttttc
aagcatgaatctctcttgaacacagtcctcaaatatgatcataaggatgaatttgaccag
caggaccatagaattgcattaaattgggctcactggtgggatcaaccaacccaagatcgt
atcctccttcccaggacaaatccagaagaatacaaatcatattccccagaagccctctgg
agctacctcacagctcaccatgataggctaagcattaccttgtggattgaagaatttcaa
gcccaggaaaccatgtcacttcagcagaacaaatggcctcctcttactgttgatgttatt
gatcagaatacttgctgcaacaattatatgaggaatgaaattttagataagctggccagg
tgtggcatttttcttacatctgagctagaagactttgagctcttcctccagagactgagc
cgtattgggggcataatacaagatactctccctgttcaaaactacaaatccaaagaaggt
tgggatttccattctcgcttcattctgtactgtttggagcacaatctgcagcatcttctg
tatgtctatcttgactattataaactttgtcctgaaaattctccctttttggaaaagaaa
gaattatatgaagctcacccttggtttgaatttttagttcaatgtcgacaagtttccagt
aacttaacagatcccaaactgatcttccaagctagtcttgcaaatgctcagattttgatt
cccaccaatcaggccagtgtaagcagcatgctcttggaaggccataccctcctggccctt
gctactacagtgtatgctcctgggggcatcagccaggttattcagaataaagaaaatgag
agctgcttgaaaaaagtggattcccaactgttgaagatggccttaactccttacccaaag
ctaaaaactgctctcttcccacagtacactgctcctagcattctgccatccgatgttaca
ctctaccacctcattcagtccttgtcaccctttgatcccagcagattgtttggctggcag
tctgccaacacactagcaataggagacgcatccagtcatcttccacatttctccagccct
gacttggtgaataaatatgctgtaatggaacgtctgaattttgcgtattacttacatcat
ggacgcccatcatttgcttttgctacttttctggtccaagaattaatcaagagtaagact
cccaagcagctgatccagcaagtaggcaaggaagcctacatcctggggctctcgtccttc
cacattccttcagtaggagctgcttgtgtctgcttcctagaattgctcggccttggcagc
ctcaagctcagagttgacatgaaagtggccaatacaattttcgagtacaggtgtagaaat
gaagatgctcagtccagctttatccgagactctctagctgaaaagttgtctaggctggcc
aatggtgataaggcagccatggaagaattgcttgttcttctggaagaaggcacgtggaac
agcattcagcagcaggacataaagaggttatccaatgaatctggcagccagtggacgtta
gtggtacagttctgcacactccacagtatgaaactgagcatgtcttaccttcgagaatgt
gccagagcaaatgattggctacagttcataactcacagccagctccatagctaccaccca
gaggaggtgaaatctcttcttcagtacttcagtccagtccttcaaagccacttaaagcta
gcttttgagaacttgccatcagtatccagctctagaacagacagtgagcaagtcttcacg
attccccaggaactccagaaaaatgaagagatggctgatttctttgaaattctccaccga
tgctcagaggagtcagactcttggctctggctcctggctgaggcagtgaaacagcaggct
cctatcctcagcatcctggcctcatgtctccagggtgccagtgctattccctgtctctgt
gtttggattgtcacttctgtggaggacagcattgcagctgaagcgatgggtcacattcag
gtctcaatagaggaccatacatgggaccttggggacctttccatcatctggagaactttg
ctaacaaagcagaagagcagcactctcatccaagggttccaacttttctttaaggattct
ccacttctattgatgatggaggtgtatgaactgtgcatgttcttcaagaattataagaaa
gccagagccaagcttctggagttccagaaaagtcttggaatgcttgatatagcagctaca
agggtcttccctaacatacctgccgcatgggtgaaggatcaggtgtgtttccttttgaaa
cttatgccacagcagtgccagacgcagtacgagctagggcagctgctgcagctgtttgtt
ggagtggagcatctcttctctgatgggccagatatgaggaagctatgtgtccttagccaa
attttgaaggatacatctataaccatcaatcatgcagttattaccagctacagcattgag
aattttcaacatgaatgtagatctattttggaaaagctgaagatagatggacagtttgtt
ttggccaggacagtagcagaattagcagaattacctgtggacagcttggtcattgaagag
ataatccaggaaatgcagaccctaaaacacattgaacagtggtccctgaaacaagcaaga
attgacttctggaaaaaatgccatcagaattttaagaaaaattccatctcaaacaaagca
gcgtcttccttcttctccacgcaggcccttgtggcccgtgagcacccaactgggcaaagc
aacatcggggagcgccatctgctgctcaccctagcagggcactggattgcccaggaagag
cctgttcctgtgcaggagctggaggagctggagaagcagatctgggtctgcaggatcacc
cagcacaccctcaaagggagtcaagaagaagtagagcctagattttctcgagagatttca
actagtggtgaactttccttcgatagcttagccagtgaattttccttctccaagctcgcg
tctctgaacacttccaaatacttagaacttaatggtcttccccccaaagagacatgtgag
aacagactagattacaaggagcaggaatcactgaatgttttgattggacacctgctgaac
gacggctgtgttcacgaagcgagtagagtatgccagtatttccatttctataaccaagat
gtggccttggtattgcactgcagagccctggcctcaggagaggccagtgtggatgaccta
cacccagacatccgtgctctgcttcagagcactaagctacctgaggaagaggagagccct
agcgctcctgtacggaaagtccacagcacttcgagtttggatagtcagtcatttgtgatg
gtgccacctggtgatgagatggtgaggaatttgcgaactctgacaagcagatgcctcaat
gggaagaactactgtcggcagatcctctgtctttatgaacttgccaaggagctgggttgt
tcctatgcagatgttgctgctggggatggtgaggtcatgctccgggcaatcctgtcctct
cagcagcctgaccgatgcaaacaagcccaggccttcatcagcacccagggcctcaagcca
gacactgtggctgaactagtggctgaagaggtgactcgagagctgctgactccatctgag
ggaacaggacaaaagcagatattcaatgcaacagaggaaagtcagatatttcttcagcta
actgccctgtgtcaagaccgcacattggtaggcatgaagctgctggataagatttcctcc
gttccccttggggaactgtcttgcaccacagagctcctgatcctggcccatcactgcttc
accctaacttgccacatggagggcatcatcagagtcctacaggctgcccgcatgcttaca
gataaccacttggctcccaacgaggagtatggtctggtggtgcgcctcctcaccggcatt
ggaaggtacaatgagatgacatacatctttgatttactgcataaaaagcactattttgaa
gttctgatgaggaagaagctggatccgagtggtaccctgaagacagccctgctggactac
attaaacgctgccaccctggagacagtgaaaagcacaacatgattgccctgtgcttcagc
atgtgccgggagataggggagaaccatgaggcagcggcctgcatccagttgaaactgatc
gagtctcagccctgggaggatagcctcaaggatggaccccacctgaagcagctcctgctt
aaggctctgactttgatgctggatgcagcagagagttatgccaaggactcctgtgtacgg
caagccctgcactgtaaccggctcaccaagttgataacactacagattcactttctgaac
agtggccagaacacaatgctcatcaacttgggtcatcataagctaatggactgtatcatg
gccttacctcgcttctaccaggcttctattgtagctgaggcctatgactttgttcctgac
tgggctgaagttctataccaaaaagtgattcttaaaggagactttaattatctggaagaa
tttaagcagcaaaagttattacaatccaatatatttgaagaaatttctagaaaatataaa
caacaccagcccactgacagagccacagaaaacctaaagaagttactttcgtattgtgaa
gatatctacctgtattacaagttggcatatgaacacaaattttttgaaattgtaaatgtg
cttctgaaggaccctcagacaggatgctgtctgaaagatatgcttgcaggttag
DBGET
integrated database retrieval system
