Nannospalax galili (Upper Galilee mountains blind mole rat): 103746894
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Entry
103746894 CDS
T03372
Symbol
Fh
Name
(RefSeq) fumarate hydratase
KO
K01679
fumarate hydratase, class II [EC:
4.2.1.2
]
Organism
ngi
Nannospalax galili (Upper Galilee mountains blind mole rat)
Pathway
ngi00020
Citrate cycle (TCA cycle)
ngi00620
Pyruvate metabolism
ngi01100
Metabolic pathways
ngi01200
Carbon metabolism
ngi04934
Cushing syndrome
ngi05200
Pathways in cancer
ngi05211
Renal cell carcinoma
Module
ngi_M00009
Citrate cycle (TCA cycle, Krebs cycle)
ngi_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
ngi00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
103746894 (Fh)
00620 Pyruvate metabolism
103746894 (Fh)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
103746894 (Fh)
09162 Cancer: specific types
05211 Renal cell carcinoma
103746894 (Fh)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
103746894 (Fh)
Enzymes [BR:
ngi01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.2 fumarate hydratase
103746894 (Fh)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Lyase_1
FumaraseC_C
DUF4288
Motif
Other DBs
NCBI-GeneID:
103746894
NCBI-ProteinID:
XP_008847403
LinkDB
All DBs
Position
Un
AA seq
508 aa
AA seq
DB search
MYRALRILTRSRRLLRAPPSASAPGSGGTAVLPLWPPNTALMASQNSFRVEYDTFGELKV
PTDKYYGAQTVRSTMNFKIGGPTERMPIPVIKAFGILKRAAAEVNQDYGLDPKIASAIMK
AADEVAEGKLNDHFPLVVWQTGSGTQTNMNVNEVISNRAIEMLGGELGSKKPVHPNDHVN
KSQSSNDTFPTAMHIAAAMEVNEVLLPGLQKLHDALSTKSKEFAQVIKIGRTHTQDAVPL
TLGQEFSGYVQQVQYAMARIKAAMPRIYELAAGGTAVGTGLNTRIGFAEKVAAKVASLTG
LPFVTAPNKFEALAAHDALVELSGAMNTTACSLMKIANDIRFLGSGPRSGLGELILPENE
PGSSIMPGKVNPTQCEAMTMVAAQVMGNHVAVTVGGSNGHFELNVFKPMMIKNVLHSARL
LGDASVSFTENCVVGIQANTERINKLMNESLMLVTALNPHIGYDKAAKIAKTAHKKGSNL
KETAIELGYLTAEQFDEWVKPKDMLGPK
NT seq
1527 nt
NT seq
+upstream
nt +downstream
nt
atgtaccgtgcactccggatcctcacgcgctcgcgtcgcctgctgcgggccccgccgtcg
gcctctgctccgggctcgggtggcacggccgtcctcccgctgtggcccccgaacaccgcc
ctcatggcaagccaaaattccttccgtgtagaatatgatacctttggtgaactgaaggtc
ccaaccgataagtactatggtgcgcagacggtgaggtctacaatgaactttaagatcgga
ggtccaacagaacgcatgccaatccctgttattaaagcctttggcattttgaagcgagct
gccgctgaagtaaaccaggattatggtcttgatccaaagattgctagtgcaataatgaag
gcagcagatgaggtagctgaaggtaaattgaatgatcattttcctcttgtggtgtggcag
actggatcaggaacccagacaaatatgaatgtgaatgaagtcatcagcaacagagccatt
gaaatgttaggcggggaacttggcagtaagaaaccagtgcaccccaatgatcacgttaat
aaaagccagagctccaatgatactttccctacagcaatgcacatcgctgctgcaatggaa
gttaatgaagttctgttaccaggactgcagaagctgcacgatgctctcagtacaaaatcc
aaagagtttgcacaggtcatcaaaatcgggcggactcacacgcaggatgctgttccgctt
actcttgggcaggagttcagtggttatgttcaacaagtacagtatgcgatggcgcgaatt
aaagctgccatgccgagaatctacgagctcgcagctggaggcactgctgtcggcaccggg
ttaaacactagaattggctttgcagaaaaggttgctgcaaaagtggcctcactcacaggc
ttgccttttgtcactgctccaaataagtttgaagctcttgctgctcacgatgctctggtt
gaactcagtggagccatgaacaccacagcctgcagtctgatgaagatagcaaatgacatt
cgttttctgggttctggtcctcggtcaggtctgggagaactgatcttgccagagaacgaa
ccagggagcagtatcatgccaggcaaggtgaaccctactcagtgtgaagcgatgaccatg
gttgcagcccaagtcatggggaatcacgtggccgttactgttggaggcagcaatggacat
tttgagttgaatgtttttaaaccaatgatgattaagaacgtgttacactccgccaggctg
ctgggggatgcttctgtttccttcacagaaaactgtgtggtggggatccaggccaacaca
gaaaggatcaacaagctaatgaacgagtctctaatgttggtgaccgctcttaatcctcat
ataggctatgacaaggcagcaaagattgccaagactgcacacaagaaaggatcaaactta
aaggaaacagctattgaacttggctacctcacagcagagcagtttgatgagtgggtgaaa
cctaaggacatgctgggtccaaagtga
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