KEGG   Nannospalax galili (Upper Galilee mountains blind mole rat): 103747194
Entry
103747194         CDS       T03372                                 
Symbol
Lrrk1
Name
(RefSeq) leucine rich repeat kinase 1
  KO
K08843  leucine-rich repeat kinase 1 [EC:2.7.11.1]
Organism
ngi  Nannospalax galili (Upper Galilee mountains blind mole rat)
Brite
KEGG Orthology (KO) [BR:ngi00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ngi01001]
    103747194 (Lrrk1)
Enzymes [BR:ngi01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     103747194 (Lrrk1)
Protein kinases [BR:ngi01001]
 Serine/threonine kinases: TKL group
  LRRK family
   103747194 (Lrrk1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr LRR_8 COR-B LRR_4 Ank_2 Roc COR-A Ank LRR_1 Ank_3 LRR_14 Arf Ank_4 Ank_KRIT1 LRR_EndoS Ank_5 Ras LRR_LRWD1 Gtr1_RagA MMR_HSR1 Beta-prop_LRRK2 TniB
Other DBs
NCBI-GeneID: 103747194
NCBI-ProteinID: XP_008847761
LinkDB
Position
Un
AA seq 2004 aa
MSQRPPSMYWCVGPEGSTECPGGAMETHNGARDMGSKLSAPGDDSTVRPPSTEDIHTAYK
QRDLSRARDLLREACEESESQLEKGQLLSISAAHGDLEIVRYLLTEKHVELPTEPTDDNP
AVVAAHFGHTEVVQELLESLSGSCSTQRLLNWMLALACQRGHLEVVKLLVLTHGADPESY
AVRKNEFPAIVCLPLYAAIKSGNEDIAIFLLRHGAFFCSYILLDSPDPSKHLLRKYFIDT
STQPSSCLGKPALRVRWSHLKLPWVDLDWLIDISCQITELDLSANCLPSLPSVIPWGLIN
LRKLNLSDNHLGELPYVQSSDEIICSRLLEIDISSNKLSHLPPGFLHLSKLQKLTASKNY
LEKLFEEENATNWIGLRKLQELDLSDNKLTELPALFLHSFKSLTYLNVSRNSLKAFPDPW
ACPLKSCKASKNILESLPEKMAVFWKNHLKDVDFSENMLKEVPLGLFQLDALMFMRLQGN
QLVALPPQEKWTCRQLKTLDLSRNQLGKNEDGLKTKRISFFTTRGRQRSGTEAACMLEFP
AFLSESLEVLCLNDNHLDAVPPSVCLLKNLSELYLGNNPGLRELPPELGQLGNLWQLDIE
DVNISNVPAEIRKEGPKAILSFLRAQLRKAEKCKLMKMILVGPPRQGKSTLLEILQTGRA
PQVAHSEATIRTTKWELQRPTGSKAKVESVEFNVWDIGGPASMATVNQCFFTDKALYVVV
WNLALGEEAVANLQFWLLNIEAKAPNAVVLVVGTHLDLIEAKFRVERIATLRAYVLALCR
SPSGSRATGFPDITFKHLHEISCKSLEGLEGLRQLIFHITCSMKDVGSTIGCQRLAGRLI
PRSYLSLQEAVLAEQQSRSLGDEVQYLTDRQLEQLVEQTPDNDIKDYEDLQSAISFLIET
GALLHFPDTSHGLRNLYFLDPIWLSECLQRIFNIKGSRSVAKNGVIRAEDLRMLLVGTGF
TQQTEEQYFQFLAKFEIALPVANDSYLLPHLLPSKPGLDTHSMRHPTANTIQRVFKMSFV
PVGFWQRFIARMLISLAEMDLQLFENKKNTKSRNRKVTIYSFTGNQRNRCSTFRVKRNQT
IYWQEGLLVTFDGGYLSVESSDVNWKKKKSGGIKIICQSEMRDFSAMAFITDHVNSLIDQ
WFPALTATESDGTPLMEQYVPCPVCETSWAQHEDPSEKSESVQYFDMEDCVLTAIEQDFI
ACPRHPDVLVPLQELVPELFMTDFPARLFLENSMLEHSEGESSILGQGGSGTVIYRARYQ
GQPVAVKRFQIKKFKNSANAPADTMLRHLRAMDAMKNFSDFRQEASMLHALQHPCIVSLI
GISIHPLCFALELAPLSSLNTVLSENAKDSSFMPLGHMLTQKIAYQIASGLAYLHKKNII
FCDLKSDNILVWSLDIKEHINIKLSDYGISRQSFHEGALGVEGTPGYQAPEIRPRIVYDE
KVDMFSYGMVLYELLSGQRPALGHHQLQIAKKLSKGIRPVLGQPEEVQFHRLQALMMECW
DTRPEKRPLALSVVSQMKDPTFATFMYLLPCGKQSAFFSSQGQEYTVVFWDGKEESRNYT
VVNTEKGLLEVQRMTCAGMKLSCQLKVQSSVWTATEDQKIYIYSLKGMCPLSMPQRALDT
PAIVTCFLAVPIIKKNSFVVLAGLADGLVAVYPVIRGTPKESCSYLCSHTANRSKFGIPD
DDSRQNPYPVKAMEVVNSGSEVWYSNGPGLLIIDCLALDISRRLEPYTAPSIVTSVVCSS
DCKGEEVVWCLDDKTNSLVMYHSATYQLCARYFCGDPSPLRDMFPVKPLGPEAPDTHITT
PKEPEEECIADVTIMYSEELGTQILTHQDSVTDYCSMSSYSSSPPHRDPRSPSSLPSSPT
SYSSVPFSTDYEPSVTSDRSDHDLTPMDGDTFNQHLQAVKVLAVKDLIWVPRRGGDIIII
GVEKNSSAQRGRVIAVLKARELTPHGVLMDAAVVAKDTVVCGFANENTEWCLAVWRGWGT
REFDIFYQSYEELGRLEACTRKRR
NT seq 6015 nt   +upstreamnt  +downstreamnt
atgtcacagagaccacccagcatgtactggtgtgtggggccagagggatctaccgagtgt
ccaggaggcgccatggagacccataatggtgccagagatatgggcagcaaactgtctgcg
ccgggtgatgactccacagtacggccccccagcacagaagacattcacactgcctacaag
cagagagacctctcccgggcccgtgacctgctcagggaagcttgtgaagagagtgaatcc
cagctagagaagggtcagctactgagcatctcagcagcccatggggatctggagatcgtt
cgatacctactcacagagaaacatgtagagctgccaacagagcccacggatgacaaccca
gctgtggtggcagcacattttggacacactgaagttgtacaggaattgctagagtcctta
tcaggttcctgcagcacccagagactgctgaactggatgctggccctggcttgccagcga
gggcacctggaggttgtaaagctgctggtcctgacacatggggctgacccagagagctac
gctgtcaggaagaatgaattccccgccatcgtgtgcttgcccctctatgctgccatcaaa
tcagggaatgaagacattgccatattcctgctacggcacggggcctttttctgttcctac
atcctactggacagccctgaccccagcaagcatctgcttaggaagtatttcatcgatacc
agcacccagcctagcagctgccttggaaaaccagcacttcgggtgagatggtcccatctc
aagttgccctgggtggatctcgactggctcatagacatctcctgccagatcacagagctt
gatctctctgccaactgcctgccttccctcccctcagtcatcccctgggggctcatcaac
ctgagaaagctgaacctctcagacaaccacctgggggagctgccctatgtgcagtcatct
gatgaaatcatctgttccaggttacttgaaattgacatttccagcaacaagctgtcccac
cttccgcctggattcttgcacctctcaaaacttcaaaaactgacagcttcaaagaattat
ttggaaaagttgtttgaagaagaaaatgccactaactggatcggcctgcggaagctgcag
gaacttgatttatctgataataagctgaccgagctccctgcccttttcctgcactccttc
aagtcgctcacctatctgaatgtttccagaaacagcctgaaggcctttccagatccctgg
gcctgccctttgaaatcttgcaaagcctccaaaaacatcttggaatcgctgccagaaaaa
atggctgtcttttggaaaaatcaccttaaggatgtggatttttcagaaaacatgctaaaa
gaagttcctctgggtctttttcagcttgatgccctcatgttcatgaggttacaggggaac
cagctggtggcactgccacctcaagagaagtggacttgcagacaactcaagaccctggac
ctctccagaaaccaactcggcaaaaatgaagatgggcttaaaacaaagcgtatctcattt
ttcaccaccagagggcgccagcgttcagggactgaggcagcatgtatgttagaatttcca
gctttcctaagtgagtctttggaagtcctttgtctgaatgacaaccaccttgacgcagtt
cctccttcagtttgccttctcaagaacttatcagagctctacctgggaaacaaccctggc
ctccgggagctccctcctgagctaggtcagctgggaaacctctggcagttggatattgaa
gatgtgaacatcagcaacgtgcctgcagagatcaggaaagaaggccccaaagcaatactg
tctttcctgcgtgctcagctgcgcaaagcagagaagtgcaagctgatgaagatgatcctc
gtgggccccccacgccagggcaagtccacactcctggagatcttacagacggggagggcc
ccccaggtggcacacagcgaggccaccatcaggaccaccaaatgggagctccagaggccc
acaggctccaaagccaaggttgagtccgtggagttcaatgtctgggacatcgggggccct
gccagcatggccacagtcaatcagtgcttcttcaccgacaaggccctgtacgtggtggtc
tggaacctggcactgggggaggaagctgtggccaacctccagttttggctgctcaacatt
gaggccaaggccccaaatgctgttgtgctggtggtcgggacacacttagacctaattgaa
gccaaattccgagtggagaggatagcaacactgcgtgcctatgtgctggcactctgccgc
tcaccctcaggatccagagccacaggcttcccagacatcacattcaaacacttacatgag
atctcctgtaagagtctagaaggactggaaggacttcggcagctgattttccacatcaca
tgcagcatgaaggatgtgggtagcaccatcggctgccagagactcgctggcaggctgatc
cccaggagctacctgagcctgcaggaggcagtgctagccgagcagcagagccgcagcctg
ggtgatgaagtacagtacctgacagacaggcagctggagcagctggtggagcagacacct
gacaatgacatcaaagactatgaggacctgcaatctgccatcagcttcctcatagaaaca
ggagccctgctgcacttcccagacaccagtcatggcctgagaaatctctacttccttgac
cccatttggctgtctgaatgtctacagaggatcttcaacatcaagggctctcgttcagtg
gcaaagaacggcgtgatccgagcggaggacctcaggatgctgctggtggggactggcttc
acgcagcagactgaggagcagtactttcagttccttgccaagtttgagattgccctgcct
gttgccaatgacagctacctcctgcctcatctccttccatccaagcctgggctggatacc
cacagcatgcggcacccaacagccaacaccatccagcgggtgtttaagatgagcttcgtc
cccgttggcttctggcaaaggttcatagcacggatgctgatcagcttagctgagatggac
ctacagctttttgaaaacaagaagaatactaaaagcaggaacaggaaagtcaccatttat
agttttacaggaaaccaaagaaatcgctgcagcacattcagagtgaagagaaatcagacc
atctactggcaagaagggctgctggttacctttgatggaggctacctcagtgtggaatcc
tctgatgtcaactggaaaaagaaaaaaagtggaggaattaaaatcatctgccagtcagaa
atgagggacttctcagcaatggcgtttattacagaccatgtcaactccctgatcgatcag
tggtttcctgccctgacagccacagaaagtgatggaacaccactcatggagcagtatgtg
ccctgcccagtctgtgagacatcctgggcccagcatgaagatccaagtgagaagtcagag
agcgtacaatacttcgatatggaagactgtgtgctgacagctattgagcaggacttcatc
gcctgccccagacacccagatgtcctagtgccactacaggagctagtcccagagctgttc
atgactgacttcccagccaggctcttcctggagaacagcatgctggagcacagtgagggt
gaaagcagcatcctgggccaaggtggcagtggcacagtcatataccgggcccggtaccag
ggccagcctgtggctgtgaagagatttcagatcaagaagttcaagaattctgctaatgcc
ccagcagacaccatgctgaggcacctgagggccatggatgccatgaagaacttctcagac
ttccggcaggaggccagcatgcttcatgccctgcagcacccctgcatcgtgtcactcatt
gggatcagcattcacccactctgctttgccctggagctcgccccactgagcagcctcaac
accgtgctttctgagaatgccaaagattcttcctttatgcccctgggacacatgctcacc
caaaaaatagcctaccaaattgcctcgggcctggcctacctacacaagaagaacatcatc
ttctgtgacctcaagtcagacaacatcctagtgtggtccctggacatcaaggaacacatc
aacatcaagctctcagactacggcatctcacgccagtcctttcatgagggcgccctgggt
gtggagggcacccccggctaccaggctccagagatcaggcctcgcattgtgtatgacgag
aaggtagatatgttctcctatgggatggtgctgtatgagttgctttcgggacagcgtcct
gcactgggccaccaccaacttcagattgccaagaagctgtccaagggcattcgccccgtt
ctgggtcagccagaggaagtacagttccatcgactccaggcgctcatgatggagtgctgg
gacacaaggcccgagaagcgcccactggctttgtctgtggtgagccagatgaaggaccca
accttcgccaccttcatgtacctgctgccctgcgggaagcagtcagccttcttctcctcc
cagggccaggagtacaccgtggtgttctgggatgggaaagaggaatccaggaattacaca
gtggtgaacacagagaagggccttctggaagtgcagaggatgacctgtgctgggatgaag
ctgagctgccaactcaaggtccagagctcagtgtggacagccaccgaggatcaaaaaatc
tacatctatagcctcaagggcatgtgcccattaagcatgccccagcgggccctggacaca
ccagccattgtcacctgcttcttggcagtgcccattattaaaaagaactcctttgtggtg
ctggcaggcctggctgacggacttgtggctgtgtatcctgtgatacggggaaccccaaaa
gaaagctgctcttacctgtgctcacacacagccaacaggtctaagttcggcatcccggat
gacgactcacggcagaacccttacccagtgaaggccatggaggtggtcaacagtgggtct
gaggtctggtacagcaatgggccgggccttctcatcattgactgcctagccctggatatc
agcaggcggctggagccctacacagccccctccatagtcacctcagttgtgtgcagttca
gactgcaaaggggaggaggtggtatggtgtctagatgacaagaccaattccttggtgatg
taccattcagccacctatcagttgtgtgcccgatacttctgtggggaccccagtcccctc
agggacatgtttcctgtgaaacccctgggcccagaagccccagacacgcacataactacc
ccaaaggagcctgaggaggaatgcattgcagatgtgaccatcatgtacagcgaggagctg
ggcacgcagatcctaacacaccaggactcagtcactgactactgctctatgtcttcctac
tcttcatccccacctcaccgagatcccaggtccccttccagcctgcccagttccccaacc
agctattccagtgtgcctttctccactgattacgagcccagtgtcacctctgacaggtct
gatcatgacctgacccccatggatggggatacattcaaccaacacctgcaggcagtgaag
gtccttgctgttaaagatctcatttgggtccccaggcgtggtggagatattattattatt
ggtgtggagaagaattcgagtgcccagcggggccgagtcattgctgtattaaaagcacga
gagctgactccacatggggtactaatggatgcagcagtggtggcaaaggatacggtggtg
tgcggctttgcaaatgaaaacacagagtggtgcctggctgtctggaggggctggggcacc
agggagtttgacatcttctaccaatcgtatgaagagctgggccggctggaagcttgtaca
cgcaagagaaggtaa

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