Nannospalax galili (Upper Galilee mountains blind mole rat): 103748375
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Entry
103748375 CDS
T03372
Symbol
Srd5a2
Name
(RefSeq) steroid 5 alpha-reductase 2
KO
K12344
3-oxo-5-alpha-steroid 4-dehydrogenase 2 [EC:
1.3.1.22
]
Organism
ngi
Nannospalax galili (Upper Galilee mountains blind mole rat)
Pathway
ngi00140
Steroid hormone biosynthesis
ngi01100
Metabolic pathways
ngi05215
Prostate cancer
Module
ngi_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
ngi00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
103748375 (Srd5a2)
09160 Human Diseases
09162 Cancer: specific types
05215 Prostate cancer
103748375 (Srd5a2)
Enzymes [BR:
ngi01000
]
1. Oxidoreductases
1.3 Acting on the CH-CH group of donors
1.3.1 With NAD+ or NADP+ as acceptor
1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
103748375 (Srd5a2)
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Ortholog
Paralog
GFIT
Motif
Pfam:
Steroid_dh
DUF1295
Motif
Other DBs
NCBI-GeneID:
103748375
NCBI-ProteinID:
XP_008849217
UniProt:
A0A8C6RKD4
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All DBs
Position
Un
AA seq
254 aa
AA seq
DB search
MPGACQQSSVLAGSATLITLGALIVFSGKPGGYGKHTLSGTSGARSLPARIAWFVQELPA
FLASAGMLTQQPGPLFGHPGNVLLGLFCVHYFHRTFIYSLLTRGRPFPVVIFLRATAFCI
GNGLFQGYYLTYCAEYPEEWYTDGRFSLGVFLFILGMGINIHSDYILRQLRKPGEVIYRI
PQGGLFTYVSGANFLGEIIEWTGYALATWSLPGLGFAFFSLCFLGLQAFHNHRFYLRMFK
DYPKSRKVLIPFIF
NT seq
765 nt
NT seq
+upstream
nt +downstream
nt
atgcctggtgcgtgccagcagagctcggtactggcaggtagcgccactttgatcaccctg
ggggccctgattgtgttctctgggaaacccggcggctacggcaagcacaccctgagcggg
acgtcaggagctcgcagcctgccggcccgcatcgcctggttcgtgcaggagctgccagcc
ttcttggcgtcggcgggaatgcttacccagcagccaggtcctctcttcggacatcccggg
aacgtgctgctgggtctcttctgcgtacattacttccacaggacatttatttactccttg
ctcaccagagggaggccttttccagttgtgatctttttgagagcaactgccttctgcatt
ggaaatggattatttcaaggctactatctgacttactgtgcagaataccctgaagagtgg
tatacagatggacggtttagtttgggtgtcttcctatttattttggggatgggaatcaac
attcatagtgactacatattgcgccagctcaggaagcctggagaagtcatctataggatt
ccacaaggtggcttgtttacatatgtttctggagccaatttcctgggtgagatcatcgag
tggacaggctatgccttggccacctggtccctgccaggacttggatttgcatttttctca
ctgtgtttccttgggctacaagcttttcacaaccacaggttctacctcaggatgtttaag
gactatccaaaatctcggaaagtgcttattccattcatcttttaa
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