Nannospalax galili (Upper Galilee mountains blind mole rat): 103748812
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Entry
103748812 CDS
T03372
Symbol
Pde3a
Name
(RefSeq) phosphodiesterase 3A
KO
K19021
cGMP-inhibited 3',5'-cyclic phosphodiesterase A [EC:
3.1.4.17
]
Organism
ngi
Nannospalax galili (Upper Galilee mountains blind mole rat)
Pathway
ngi00230
Purine metabolism
ngi01100
Metabolic pathways
ngi04022
cGMP-PKG signaling pathway
ngi04024
cAMP signaling pathway
ngi04924
Renin secretion
ngi05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
ngi00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
103748812 (Pde3a)
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
103748812 (Pde3a)
04022 cGMP-PKG signaling pathway
103748812 (Pde3a)
09150 Organismal Systems
09152 Endocrine system
04924 Renin secretion
103748812 (Pde3a)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
103748812 (Pde3a)
Enzymes [BR:
ngi01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase
103748812 (Pde3a)
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SSDB
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Paralog
GFIT
Motif
Pfam:
PDEase_I
TgpA_N
Motif
Other DBs
NCBI-GeneID:
103748812
NCBI-ProteinID:
XP_008849822
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All DBs
Position
Un
AA seq
1186 aa
AA seq
DB search
MAELASGKLEVSRSSWRPGEFSASSKFAWIREKEEGFLGRAPEAPGRARGTRLGSPCRAH
SMAVPGDRQQPGPGGSSPARVAIPRASPPSTRGSPGLQPLRRSRQLSSALCAGSVSLLLA
LLVRLVGGEVGGLEPSPEAAAEEEGAAGGAGGGVVPGPRGGAPGGGAAPSPWLQPAALLL
SLLCAFFWMGLCLLRAGVRLPLAVALLAACCAGEALLQLALGVGDARLPSLPAAGLLLGC
LAAATWLGLRLRLGVLMIAGTSALRTVALLSLERFKVAWRPYLAYLACVLGLLLARYAEQ
ILPQSDRAAPPRELCASQLRIKEEIPGPKRRRRSSSVVAGEMSGCSSKSHRRTSLPCIPR
EQLMGHSEWDHKRGPRGSQSSGTSITVDIAVMGEAHGLITDLLADPSLPPNVCTSLRAVS
NLLSTQLTFQAIHKPRLNPTMCFSENYTCSDSEENLEKDKLAIPKRLRRSLPPGLLRRVS
STWTTTTSATGLPTLEPAPVRRDRSASMKLHEASSPSAVNPDSWNTPVLMTLTKSRSFTS
SYAVSAANHVKAKKPNRPGGLAKISPLSSPCSSPPQGTPVSSPVSKLSSARFPESSETTA
KQGPASHRALTYTQSAPDLSPQIPPPPVICSSCGRLYSEGNSADGPLLERSGPATRKPNR
TDDTVQVTSDYETNNNSDSSDILQNEDEAECPGEPPRKASTCGTYTPESMIFLDKPILAP
EPLVMDNLDSIMEQLNTWNFPIFDLVENIGRKCGRILSQVSYRLFEDMGLFEAFKIPIRE
FMNYFHALEIGYRDIPYHNRIHATDVLHAVWYLTTQPIPGLPTVINDHGSTSDSDSDSGF
THGHMGYVFSKMYHVPDDKYGCLSGNIPALELMALYVAAAMHDYDHPGRTNAFLVATSAP
QAVLYNDRSVLENHHAAAAWNLFMSRPEYNFLVNLDHVEFKHFRFLVIEAILATDLKKHF
DFVAKFNAKVNDDVGIDWSNENDRLLVCQMCIKLADINGPAKCKELHLQWTEGIVNEFYE
QGDEEASLGLPISPFMDRSAPQLANLQESFISHIVGPLCHSYDSAGLMPGKWVEDSDESG
DTDDPEEEEEEAGAANEETCENREAQRKKTFKRRKVYCQITQHLLQNHTMWKKVIEEEQR
LAGIESQSLDQAPQQHSAEEIQAIKEEEEEQGRPRAEEIPVPQPGL
NT seq
3561 nt
NT seq
+upstream
nt +downstream
nt
atggctgagcttgccagcggaaaacttgaagtctccaggagcagctggcgccccggggag
ttctccgcaagctcaaagtttgcgtggatccgcgagaaggaggagggattcctagggagg
gctccggaagcgccaggacgcgcgcgtgggaccaggttggggtctccctgcagagcgcat
agtatggcagtgcccggagacaggcagcagcccggcccgggagggtcgagtccagccagg
gtggccatcccccgcgcgtcccctccatccacgcggggctccccggggctgcagccgctc
cggcgctcgcggcaactttcctccgcgctgtgcgcgggctccgtgtctctcctgctggcg
ctgctggtgagactggtcggcggggaggtcggagggctggagcccagtccagaggcggcg
gcggaggaggagggagcggccggcggagccggagggggcgtcgtcccgggccctcgggga
ggtgctcccgggggcggtgcagcgcccagcccctggctgcaacccgccgcgctgctcctc
agtctgctctgcgccttcttctggatgggcttgtgcctcctgcgcgccggggtgcgcctg
cctctggccgtcgcgctgctggccgcctgctgcgcgggggaagcgctgctgcagctcgcg
ctgggcgtcggggacgcccgcctgccgtcgctgcccgccgcggggctgctgctcggctgc
ctggccgccgcgacatggctggggctgcggctgcggctgggcgtcctcatgatcgccggg
actagcgcgctcaggacggtggccctgctgtccttggagaggttcaaggtcgcctggaga
ccttacctggcgtacttggcctgcgtgctggggctcctgctggccaggtacgccgagcag
atcttgccgcagtccgacagggcggctcctccccgggagctctgtgcgtcccagctgagg
atcaaggaagagatcccgggccccaagaggaggaggcggtccagctctgtggtggccggc
gagatgtcaggctgcagcagcaagtcgcatcggaggacctcgctgccctgtatccccagg
gagcagctcatgggacattcggagtgggaccacaaaagaggaccacgagggtcacagtct
tcaggaaccagcatcactgtggatatcgctgtgatgggcgaggcccatggcctcatcact
gacctcctggcagacccttctctgccaccaaacgtgtgcacatccttgagggccgtgagc
aaccttctcagcacgcagctcaccttccaggccatccacaagcccagactgaaccccacc
atgtgcttcagtgagaactatacttgttcagattctgaggagaacttggagaaagataag
ctggccattcccaagcgcttgagaagaagtttgcccccaggcctgttgaggcgagtttcc
tcgacttggacaaccaccacctcagccacaggcctgcccaccctggagcctgcaccagta
cggagggaccgcagtgccagcatgaaactgcatgaagcatcatcacccagtgctgttaat
cctgattcttggaataccccagtattgatgacactcaccaagagcagatccttcacttcg
tcctacgctgtttccgcagccaaccatgtaaaggctaaaaagccaaaccgcccaggtggc
cttgctaaaatctcacctctttcctcaccctgctcctcacctcctcaaggaactcctgtc
agcagtcctgtcagcaaactttcttcagcacggtttccagaatcttctgaaacaactgcc
aagcaaggcccagcttctcacagggccttaacttatacccagagtgcccctgacctgtcc
cctcagatcccgcctccacctgtcatatgtagcagctgtggccgactttattcggaaggg
aattctgctgatggacccctcctggagagaagtggtccagccaccagaaaaccgaacaga
acagatgacactgtccaggttacctctgactatgagaccaacaacaacagtgacagtagt
gacattttgcagaacgaagatgaggcagagtgcccgggagaaccaccgaggaaagcatcg
acttgtggcacctacactcccgagtccatgatcttcctggacaaaccaattcttgctcca
gaacctctggtcatggataacctggactcaattatggaacagttaaatacttggaatttt
ccaatttttgatttagtggaaaatataggaagaaagtgcggccgtattctgagccaggta
tcatacagactttttgaagacatgggcctctttgaagcttttaaaatcccaattagagaa
tttatgaattattttcatgctttggagattggatacagggatattccttatcataacaga
atccatgccactgatgtcttacacgctgtctggtatctgactacgcagccgattcccggt
ctcccaactgtgattaatgatcatggatccacaagcgactctgattctgacagtggattt
acacacgggcacatgggatatgtgttttcaaaaatgtaccatgttccagatgacaaatac
ggatgtctgtctgggaacatccctgccttagagttgatggccttgtatgttgctgcggcc
atgcatgactatgatcacccagggaggacaaatgcgttcctggtggccaccagcgcacct
caggcggttctgtacaacgaccgttcagttttggagaatcatcatgcagccgcagcctgg
aaccttttcatgtcccggccagagtacaacttcttagttaaccttgatcacgtggaattc
aagcacttccgtttcctagtcatcgaagcgattctggccactgacctaaagaaacacttt
gactttgtagccaaatttaatgccaaggtgaatgatgatgttgggatagattggagcaat
gaaaacgatcgtctactggtttgtcaaatgtgtataaagttggctgatattaacgggcct
gctaaatgtaaagaacttcatctgcagtggacagagggcattgtcaatgaattctatgag
cagggtgatgaagaggccagccttggtttgcccataagccccttcatggaccgctctgcc
cctcagctggccaatcttcaggaatccttcatctcacatatcgtgggtcctctgtgccac
tcctatgactctgcaggtctcatgccaggaaagtgggtggaggacagtgacgagtcagga
gacacggacgacccagaagaggaggaagaggaggcaggagcagccaatgaagaaacctgt
gaaaacagggaggctcagagaaagaaaactttcaaaaggaggaaagtttactgccaaata
actcagcacctcctgcagaaccacacgatgtggaagaaagtgattgaagaggaacagcgg
ttggcaggcatagaaagccagtccctggaccaggcacctcagcagcattcggcagaggag
atccaggccatcaaggaggaagaggaagagcagggaaggccaagagcagaggagatcccg
gtcccacagccgggcctgtga
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