Nannospalax galili (Upper Galilee mountains blind mole rat): 103749467
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Entry
103749467 CDS
T03372
Symbol
Igf1r
Name
(RefSeq) insulin like growth factor 1 receptor
KO
K05087
insulin-like growth factor 1 receptor [EC:
2.7.10.1
]
Organism
ngi
Nannospalax galili (Upper Galilee mountains blind mole rat)
Pathway
ngi01521
EGFR tyrosine kinase inhibitor resistance
ngi01522
Endocrine resistance
ngi04010
MAPK signaling pathway
ngi04014
Ras signaling pathway
ngi04015
Rap1 signaling pathway
ngi04066
HIF-1 signaling pathway
ngi04068
FoxO signaling pathway
ngi04081
Hormone signaling
ngi04114
Oocyte meiosis
ngi04140
Autophagy - animal
ngi04144
Endocytosis
ngi04150
mTOR signaling pathway
ngi04151
PI3K-Akt signaling pathway
ngi04152
AMPK signaling pathway
ngi04211
Longevity regulating pathway
ngi04213
Longevity regulating pathway - multiple species
ngi04510
Focal adhesion
ngi04518
Integrin signaling
ngi04519
Cadherin signaling
ngi04520
Adherens junction
ngi04550
Signaling pathways regulating pluripotency of stem cells
ngi04730
Long-term depression
ngi04913
Ovarian steroidogenesis
ngi04914
Progesterone-mediated oocyte maturation
ngi05200
Pathways in cancer
ngi05202
Transcriptional misregulation in cancer
ngi05205
Proteoglycans in cancer
ngi05214
Glioma
ngi05215
Prostate cancer
ngi05218
Melanoma
ngi05224
Breast cancer
ngi05225
Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:
ngi00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
103749467 (Igf1r)
04014 Ras signaling pathway
103749467 (Igf1r)
04015 Rap1 signaling pathway
103749467 (Igf1r)
04066 HIF-1 signaling pathway
103749467 (Igf1r)
04068 FoxO signaling pathway
103749467 (Igf1r)
04151 PI3K-Akt signaling pathway
103749467 (Igf1r)
04152 AMPK signaling pathway
103749467 (Igf1r)
04150 mTOR signaling pathway
103749467 (Igf1r)
09133 Signaling molecules and interaction
04081 Hormone signaling
103749467 (Igf1r)
04518 Integrin signaling
103749467 (Igf1r)
04519 Cadherin signaling
103749467 (Igf1r)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
103749467 (Igf1r)
04140 Autophagy - animal
103749467 (Igf1r)
09143 Cell growth and death
04114 Oocyte meiosis
103749467 (Igf1r)
09144 Cellular community - eukaryotes
04510 Focal adhesion
103749467 (Igf1r)
04520 Adherens junction
103749467 (Igf1r)
04550 Signaling pathways regulating pluripotency of stem cells
103749467 (Igf1r)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
103749467 (Igf1r)
04914 Progesterone-mediated oocyte maturation
103749467 (Igf1r)
09156 Nervous system
04730 Long-term depression
103749467 (Igf1r)
09149 Aging
04211 Longevity regulating pathway
103749467 (Igf1r)
04213 Longevity regulating pathway - multiple species
103749467 (Igf1r)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
103749467 (Igf1r)
05202 Transcriptional misregulation in cancer
103749467 (Igf1r)
05205 Proteoglycans in cancer
103749467 (Igf1r)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
103749467 (Igf1r)
05214 Glioma
103749467 (Igf1r)
05218 Melanoma
103749467 (Igf1r)
05215 Prostate cancer
103749467 (Igf1r)
05224 Breast cancer
103749467 (Igf1r)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
103749467 (Igf1r)
01522 Endocrine resistance
103749467 (Igf1r)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ngi01001
]
103749467 (Igf1r)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
ngi04090
]
103749467 (Igf1r)
Enzymes [BR:
ngi01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
103749467 (Igf1r)
Protein kinases [BR:
ngi01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
103749467 (Igf1r)
CD molecules [BR:
ngi04090
]
Proteins
103749467 (Igf1r)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
Furin-like
Pkinase
fn3
Kinase-like
Insulin_TMD
Motif
Other DBs
NCBI-GeneID:
103749467
NCBI-ProteinID:
XP_008850569
LinkDB
All DBs
Position
Un
AA seq
1368 aa
AA seq
DB search
MKSGSGGGSPTSLWGLVFLSAALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGFLH
ILLISKAEDYRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIF
EMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYIVGNKPQKECGD
LCPGTLEEKPICEKTTINNEYNYRCWTTNRCQKMCPSVCGKRACTENNECCHPECLGSCH
TPDDNTTCVACRHYYYKGVCVPACPPGTYRFEGWRCVDRDFCANIQSAESTDSYGFVIHD
GECMQECPSGFIRNSTQSMYCIPCEGPCPKVCGDEEKKTKTIDSVTSAQMLQGCTILKGN
LLINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRMILGEEQLEGNYS
FYVLDNQNLQQLWDWNHRNLTIKSGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINT
RNNGERASCESDVLRFTSTTTWKNRIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYD
GQDACGSNSWNMVDVDLPPNKEGEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKS
EILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNGNLSYYIVRWQRQPQDGYLYR
HNYCSKDKIPIRKYADGTIDVEEVTENPKTEVCGGDKGPCCACPKTEAEKQAEKEEAEYR
KVFENFLHNSIFVPRPERKRRDVMQVANTTMSSRSRNTTVTDIYNITDPEELETEYPFFE
SRVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVT
WEPRPENSIFLKWPEPENPNGLILMYEIKYGSQVEDQRECVSRQEYRKYGGAKLNRLNPG
NYTARIQATSLSGNGSWTDPVFFYVPAKTTYENFIHLIIALPVAILLIVGGLVIMLYVFH
RKRNNSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMNRELGQGSFGMVYEGVAK
GVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIM
ELMTRGDLKSYLRSLRPEIENNPVLSPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAAR
NCMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFG
VVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSF
LEIISSIKDEMEPGFREVSFYYSEENKPPEPEELELEPENMESVPLDPSASSASLPLPDR
HSGHKAENGPGPGVLVLRASFDERQPYAHMNGGRANERALPLPQSSTC
NT seq
4107 nt
NT seq
+upstream
nt +downstream
nt
atgaagtctggctccggaggagggtccccgacctcgctgtgggggctcgtgtttctctcc
gccgcgctctcgctctggccgacgagtggagaaatctgtgggcctgggatcgacatccgc
aatgactatcagcagctgaagcgtctggagaactgcacggtgattgagggcttcctccat
atcctgctcatctccaaggctgaggactaccgcagctaccgcttccccaagcttacagtc
atcaccgaatacttgctgctgtttcgtgttgccggcctcgagagcctgggagatctcttc
ccgaacctcacggtcatccgtggctggaaactcttctacaactacgcactggtcatcttt
gagatgaccaacctcaaggatattgggctttataatctgaggaacattactcggggggct
atcaggattgagaaaaatgctgacctctgttacctctccacggtggactggtccctcatc
ttggatgctgtgtccaataactacattgtggggaacaagccccagaaggagtgtggggac
ctgtgtccagggaccttggaggagaagccaatctgcgagaagaccaccatcaataatgaa
tacaactaccgctgttggaccacaaatcgctgccagaaaatgtgccctagtgtgtgtggg
aagcgagcatgcacggagaacaatgagtgctgccacccagaatgcctgggcagctgccac
acacctgatgacaacacaacctgcgtggcctgccggcactactactacaaaggcgtgtgc
gtgcctgcctgcccgcctggcacctacaggtttgagggctggcgctgtgtggaccgagat
ttctgtgccaacatccagagtgctgagagcactgactcctatggcttcgttatccacgac
ggcgagtgtatgcaggagtgcccctcaggcttcatccgcaacagcacccagagcatgtac
tgcatcccctgtgaaggcccttgccccaaggtctgtggtgatgaagaaaagaaaacaaaa
accatcgattcagttacttctgctcaaatgctccaaggatgtaccatcttgaagggcaat
ttgcttattaatatccggcgaggcaataacatcgcctcagaactggagaatttcatgggg
ctcatcgaggtggtgacgggctatgtgaagatccgccattcccacgccctggtgtctttg
tcctttctgaaaaacctccgcatgatcttaggagaggagcaactggaaggaaactattcc
ttttatgtcctggacaaccagaacttgcagcagctgtgggactggaaccaccgcaacctg
accatcaagtcagggaagatgtactttgctttcaatcccaagctgtgtgtttctgaaatt
taccgcatggaggaagtaacaggaacaaaagggcgccagagcaaaggggacataaacacc
aggaacaacggagagcgagcctcctgtgaaagtgatgttctgcgtttcacctcaaccacc
acctggaagaaccgcattatcataacctggcaccggtaccgaccccccgactacagggat
ctcatcagcttcacggtttactacaaggaggcaccttttaaaaatgttacagaatatgat
gggcaggatgcctgtggctctaacagctggaacatggtggatgtggacctgcctcccaac
aaggagggggagcccggcattttattgcatgggctgaagccctggacccagtacgccgtc
tatgtcaaggctgtgaccctcaccatggtggaaaacgaccatatccgtggggccaagagt
gaaatcttatacattcgcaccaatgcttcagtaccttccattcccctggatgttctttca
gcatcaaactcctcctctcagctgattgtaaagtggaatcccccatctctgcccaacggg
aacctgagttactacattgtgaggtggcagcggcagccacaggatggctacctctacagg
cacaactactgctccaaagacaaaatccccatcagaaagtatgctgacggcaccattgat
gtggaagaggtgacagaaaatcccaagaccgaagtgtgtggtggggataaaggaccatgc
tgtgcttgtcccaaaactgaagctgagaagcaggccgagaaggaggaggctgagtaccgc
aaagtcttcgagaatttccttcacaactccatcttcgtgcccagacctgaaaggaaacgg
agagatgtcatgcaagtggccaacaccaccatgtccagtcgaagcaggaacaccacggtg
actgacatctataatatcacagacccagaagagcttgagacagaataccctttcttcgag
agcagagtggataataaggagagaactgtcatttccaacctccgacctttcactctatat
cgcatcgatatccacagctgcaaccacgaggctgagaagctgggctgcagtgcctccaac
tttgtctttgcaagaaccatgcctgcagaaggagcagatgatattcctggaccagtgact
tgggaaccaaggcctgaaaactccatctttttaaagtggccagaacctgagaaccctaac
ggattgattctcatgtatgaaataaaatacggatcacaagttgaggatcagcgggaatgt
gtgtccagacaggagtacaggaagtatggaggggccaagcttaaccggctaaacccaggg
aactatacagcccggattcaggctacctctctctctgggaatgggtcatggacggatcct
gtgttcttctatgtcccggccaaaacaacgtatgagaatttcatccatctgatcattgct
ctgccggtcgccatcctgctgatcgtgggcgggctggtgatcatgttgtacgtcttccat
aggaagagaaataacagcagattggggaatggggtgctgtatgcctctgtgaacccagaa
tatttcagtgcagccgatgtgtacgtgcctgatgaatgggaggttgctcgagagaagatc
accatgaaccgggagcttgggcagggatcctttgggatggtctatgaaggagtggccaag
ggtgtggtcaaggacgaacctgaaaccagggtagccatcaagacagtaaatgaggctgca
agcatgcgtgaaaggatagagtttctgaacgaggcctcagtgatgaaggagttcaactgt
caccatgtggtgcggttgctgggcgtggtgtcccagggccagcctaccctggtcatcatg
gaactaatgacacgcggggatctcaaaagttatctcaggtctctgaggccagaaatagag
aataatccagtcctatcacctccaagtttaagcaagatgatccagatggctggagagatt
gcagatggcatggcatacctcaatgcgaacaagtttgtccacagagatcttgctgcgcgg
aattgcatggtagctgaagatttcaccgtcaaaattggagattttggtatgacacgagac
atctatgagacagactactaccggaaaggagggaaggggttactgcctgtgcgctggatg
tctcctgagtccctcaaggatggagtcttcactactcattcagatgtctggtcctttggt
gtcgtcctctgggagattgccacattggctgagcagccataccaaggcttgtccaatgag
caagtccttcgcttcgtcatggagggtggccttctggacaaaccggacaactgccccgac
atgctatttgaactgatgcgcatgtgctggcagtacaaccccaagatgcggccttccttc
ctggagatcatcagcagcatcaaggacgagatggagcccggctttcgagaggtctccttc
tactacagcgaggagaacaagccacccgagccggaggagctggagctggagcccgagaac
atggagagcgtccccctggacccttcggcctcctcagcctccctgccactgcctgataga
cactcaggacacaaggccgagaacggcccaggccctggagtgctggttctccgcgccagc
ttcgatgagagacagccttatgcgcacatgaacgggggtcgagccaacgagagggccttg
ccgctgccccagtcttcgacctgctga
DBGET
integrated database retrieval system
