KEGG   Nannospalax galili (Upper Galilee mountains blind mole rat): 103749533
Entry
103749533         CDS       T03372                                 
Symbol
Fyn
Name
(RefSeq) FYN proto-oncogene, Src family tyrosine kinase
  KO
K05703  tyrosine-protein kinase Fyn [EC:2.7.10.2]
Organism
ngi  Nannospalax galili (Upper Galilee mountains blind mole rat)
Pathway
ngi04071  Sphingolipid signaling pathway
ngi04072  Phospholipase D signaling pathway
ngi04360  Axon guidance
ngi04380  Osteoclast differentiation
ngi04510  Focal adhesion
ngi04517  IgSF CAM signaling
ngi04520  Adherens junction
ngi04611  Platelet activation
ngi04650  Natural killer cell mediated cytotoxicity
ngi04660  T cell receptor signaling pathway
ngi04664  Fc epsilon RI signaling pathway
ngi04725  Cholinergic synapse
ngi05020  Prion disease
ngi05416  Viral myocarditis
Brite
KEGG Orthology (KO) [BR:ngi00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04072 Phospholipase D signaling pathway
    103749533 (Fyn)
   04071 Sphingolipid signaling pathway
    103749533 (Fyn)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    103749533 (Fyn)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    103749533 (Fyn)
   04520 Adherens junction
    103749533 (Fyn)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    103749533 (Fyn)
   04650 Natural killer cell mediated cytotoxicity
    103749533 (Fyn)
   04660 T cell receptor signaling pathway
    103749533 (Fyn)
   04664 Fc epsilon RI signaling pathway
    103749533 (Fyn)
  09156 Nervous system
   04725 Cholinergic synapse
    103749533 (Fyn)
  09158 Development and regeneration
   04360 Axon guidance
    103749533 (Fyn)
   04380 Osteoclast differentiation
    103749533 (Fyn)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05020 Prion disease
    103749533 (Fyn)
  09166 Cardiovascular disease
   05416 Viral myocarditis
    103749533 (Fyn)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ngi01001]
    103749533 (Fyn)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:ngi04131]
    103749533 (Fyn)
Enzymes [BR:ngi01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     103749533 (Fyn)
Protein kinases [BR:ngi01001]
 Non-receptor tyrosine kinases
  SRC family
   103749533 (Fyn)
Membrane trafficking [BR:ngi04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Kinases and associated proteins
    103749533 (Fyn)
 Endocytosis
  Lipid raft mediated endocytosis
   Flotillin-dependent endocytosis
    103749533 (Fyn)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase SH2 SH3_1 SH3_9 SH3_2 SH3_3 SH3_10 ABC1 Haspin_kinase SH2_1 zf-RING_14
Other DBs
NCBI-GeneID: 103749533
NCBI-ProteinID: XP_008850620
LinkDB
Position
Un
AA seq 537 aa
MGCVQCKDKEATKLTEERDGSLNQSSGYRYGTDPTPQHYPSFGVTSIPNYNNFHAAGGQG
LTVFGGVNSSSHTGTLRTRGGTGVTLFVALYDYEARTEDDLSFHKGEKFQILNSSEGDWW
EARSLTTGETGYIPSNYVAPVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESET
TKGAYSLSIRDWDDMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSERAAGLCC
RLVVPCHKGMPRLTDLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNGNTKVAIKT
LKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEEPIYIVTEYMNKGSLLDFLKDGEGR
ALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEY
TARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVE
RGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQGFLEDYFTATEPQYQPGENL
NT seq 1614 nt   +upstreamnt  +downstreamnt
atgggctgtgtgcaatgtaaggataaagaagcaacgaaactcacagaggagagggatggc
agcctgaaccagagctccgggtaccgctatggcacagatcccactcctcagcactacccc
agctttggtgtgacctccatcccaaactacaacaacttccacgcagccggaggccagggg
ctcacagtctttgggggtgtgaactcttcttctcacactgggaccttgcgtacaagagga
ggaacaggagtgacactatttgtggctctttatgactatgaagcacggacagaagatgac
ctgagttttcacaaaggagaaaagtttcaaatattgaacagctcggaaggcgattggtgg
gaagcccgctccctgacaactggagaaacgggttatattcctagcaattatgtggctcca
gtcgactctatccaagcagaagagtggtactttggaaaacttggtcgcaaagatgctgag
agacagcttctgtcctttggaaacccaagaggtacctttcttatccgcgagagtgaaacc
accaaaggtgcctattcactttccatccgtgattgggatgatatgaaaggagaccatgtc
aaacattataaaattcgtaaacttgacaatggtggatactatatcaccacccgggcccag
tttgaaacccttcagcagcttgtacagcattactcagagagagccgcaggtctctgctgc
cgtctagtagttccctgtcacaaagggatgccaaggcttaccgatctgtctgtcaaaacc
aaagatgtctgggaaatccctcgagaatccctgcagttgatcaagagactgggaaatggg
cagtttggggaagtttggatgggtacctggaatggaaatacaaaagtagccataaagacc
cttaagccaggcacaatgtctcctgagtcattcctagaggaagcacagatcatgaagaag
ttgaagcatgacaagctggtacagctctacgctgtggtatcagaggagcccatctacatt
gtcaccgaatacatgaataaaggaagtttgcttgatttcttaaaagatggtgaaggaaga
gctctgaaattgccaaatcttgtggacatggcagcacaggttgctgcaggaatggcttat
attgagcgcatgaattatatccacagagatctgcgatcggcaaacattctagtggggaat
ggactgatttgcaagattgctgactttggattggcccggttgattgaagacaatgagtac
acagcaagacaaggtgcaaagttccccattaagtggacagccccagaagcagccctgtat
ggaaggttcacaatcaagtctgatgtgtggtcttttggaatcttactcacagagctggtc
accaaaggaagagtgccatacccaggcatgaacaaccgagaggtgctggagcaggtggag
cgtggttacaggatgccctgcccacaggactgccccatctccctgcacgagctcatgatc
cactgctggaaaaaggacccggaagaacgccctacttttgagtacttgcagggcttcctg
gaggactactttacagccacagagccccagtatcagcctggtgaaaacctgtga

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