Nannospalax galili (Upper Galilee mountains blind mole rat): 103750131
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Entry
103750131 CDS
T03372
Symbol
Plce1
Name
(RefSeq) phospholipase C epsilon 1
KO
K05860
phosphatidylinositol phospholipase C, epsilon [EC:
3.1.4.11
]
Organism
ngi
Nannospalax galili (Upper Galilee mountains blind mole rat)
Pathway
ngi00562
Inositol phosphate metabolism
ngi01100
Metabolic pathways
ngi04014
Ras signaling pathway
ngi04015
Rap1 signaling pathway
ngi04020
Calcium signaling pathway
ngi04024
cAMP signaling pathway
ngi04070
Phosphatidylinositol signaling system
ngi04919
Thyroid hormone signaling pathway
ngi04933
AGE-RAGE signaling pathway in diabetic complications
ngi05205
Proteoglycans in cancer
Module
ngi_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
ngi00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
103750131 (Plce1)
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
103750131 (Plce1)
04015 Rap1 signaling pathway
103750131 (Plce1)
04020 Calcium signaling pathway
103750131 (Plce1)
04070 Phosphatidylinositol signaling system
103750131 (Plce1)
04024 cAMP signaling pathway
103750131 (Plce1)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
103750131 (Plce1)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
103750131 (Plce1)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
103750131 (Plce1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
ngi04131
]
103750131 (Plce1)
Enzymes [BR:
ngi01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
103750131 (Plce1)
Membrane trafficking [BR:
ngi04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
103750131 (Plce1)
Endocytosis
Macropinocytosis
Phospholipase C
103750131 (Plce1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PI-PLC-X
PI-PLC-Y
RasGEF
RA
C2
EF-hand_like
GDPD
Motif
Other DBs
NCBI-GeneID:
103750131
NCBI-ProteinID:
XP_017658674
UniProt:
A0A8C6RK88
LinkDB
All DBs
Position
Un
AA seq
2291 aa
AA seq
DB search
MTSEEMEASVLIPVTQRKVSAQSAAEERATDTTIPMAHAVRQGVQIPNAISRWNKPKAES
SGSDLPKVVSIAREKIVSDENHNEKCWEKNVPDSVENHNINCESLLQNQHGLPQSQLCEM
CDSVTKEGLSLETGIPSPLERKVFPGIQLEMDDPPMDISPLGNQSGILETSSPHPDSNMA
LFHLHYEVDRRMSGTLHTLSENFILDDCGNCVTLPEGQQKKNFMAYTCKLMELAKTCGNK
NGQLWCDHCNTLHDKYLCFERSRPKVSVVCSSESFCRDGFAHNLPAKTFLNSLEDFSGNC
EDVEEDFFKNKKERSTLLVRRFCKNDREVKKSVYTGTRAIVRTLPSGHIGLTAWSYVDQK
RNSLLPPCGKVMDPPSTMNIRQSGSQRLSETQWHLIYNAVRQGEETEDTVGSLLHCFTKL
PASEPALGRIRDGLCLKRCVRDTLCEYRATLQRTSISRYVTGSLLEATTSLGARSGLLST
FGGSTGRMMLKERQPGTSMANSSVLPSSSAGISKELIDLQPLIQFPEEVASILTEQEQSI
YRKVLPMDYLCFLTQDLGSPECQRSLPCLKASISASILTSQNDEHNTLEDLLMRFNEVSS
WVTWLILTAGSMEEKREVFSYLVHVAKCCWNMGNYNAVMEFLAGLRSRKVLKMWQFMDQS
DIETMRSLKDAMAQHESSVEYKKVVTRALHIPGCKVVPFCGVFLKELCEVLDGASGLLKL
CPRYNSQEEALEFVADYSGQDNFLQRVGQNGLKNSEKESTVNNIFQIIRSCSRSLETEEE
DSSSEGNSSRKNSLKEKTQWQFIIGDLLDSENDIFEQSKECDPHGSEESHKAFDHGTELI
PWYVLSIQADVHQFLLQGATVIHYDQDTHLSARCFLQLQLDNSTLTWMKPPTTSPAGARP
KLGMLSNMAEPGKFPSLGSAGLSSLTEGILDLFSVKAVYMGHPAIDIHTVCVQNKLSSMP
LSETGVTLLYGLQTTDNRLLHFVAPKHTAKMLFSGLLELTTAVRKIKKFPDQRQQWLRKQ
YVSLYQEDGRYEGPTLAHAVELFGGRRWSTRNASPGISAKNAEKPNMQRNNTLGISTTKK
KKKMLMRGESGEATDDEMATRKAKVYRECRSRSGSDPQDINEQEESEVNATTNSPNPLHS
RRAHSLTTAGSPNLSAGMSSPISSWSSSSWHGRIKGGMKGFQSFMVSDSNMSFVEFVELF
KSFSVRSRKDLKDIFDIYSVPCNRSGSESAPLYTNLTIEENTSDLQPDLDLLTRNVSDLG
LFIKSKQQLSDNQRQISDAIAAASIVTNGTGIESTSLGIFGVGILQLNDFLVNCQGEHCT
YDEILSIIQKFEPSISMCHQGLMSFEGFARFLMDKDNFASKNDESQENKKELQLPLSYYY
IESSHNTYLTGHQLKGESSVELYSQVLLQGCRSIELDCWDGDDGMPIIYHGHTLTTKIPF
KEVVEAIDRSAFITSDLPIIISIENHCSLPQQRKMAEIFKNVFGEKLVAKFLFETDFSDD
PMLPSPDQLRRKILLKNKKLKAHQTPVDILKQKAHQLASMQAQAYNGGNANPLPTNNEEE
EDEEDEYDYDYESLSDADVLTASPAPKGQEDNILEDRPENKSCADKLQFEYNEEIPKRIK
KADNSSCNKGKVYDMELGEEFYLPQNKKESRQIAPELSDLVIYCQAVKFPGLSTLNSSGS
SRGKERKSRKSIFGNNPGRMSPGETASLNKTSGKSSYEVIRQTWEESSPLNPTTSLSAII
RTPKCYHISSLNENAAKRLCRRYSQKLIQHTASQLLRTYPAATRIDSSNPNPLMFWLHGI
QLVALNYQTDDLPLHLNATMFEANGGCGYVLKPPVLWDKSCPMYQKFSPLERDLDNMDPA
IYSLTIVSGQNVCPSNSTGSPCIEVDVLGMPLDSCHFRTKPIHRNTLNPMWNEQFLFRVH
FEDLVFLRFAVVENNSSAVTAQRIIPLKALKRGYRHLQLRNFHNEVLEISSLFINSRRME
ENSSGGTMPASLMFNTEERKCSQTHRVTVHGIPGPEPFAVFTINGGTKAKQLLQQVLATE
QDTKLIAMDYFLMEEKHFISKEKNDCKKQPFQRAVGPEEDIMQILSSWFPEEGYVGRIVL
KPQQETLEEKSIVQDDKEVILSSEESFFVQVHDVSPEQPRTVIKAPRVSTAQDVIQQTLC
KAKYSYSILSNPNPGDYVLLEEVMKDAPNKKSSNPKSSQRILLDQECVFQAQSKWKGAGK
FILKLKEQVQASREDKRRGISFASELKKLTKSTKQSRGLIPPQLVASESVQSKEEKPMGA
LSSSDTMDYRQ
NT seq
6876 nt
NT seq
+upstream
nt +downstream
nt
atgacttctgaagagatggaagcttccgttctcatcccagtgactcagagaaaagtgtct
gcccagtcagctgcagaggaaagggccacagacaccactataccaatggcgcatgctgtc
aggcagggtgtgcagattccgaatgccatctcacggtggaacaaacctaaagcagaatct
tctggaagtgatttgcccaaggttgtctcaatagcaagggagaaaatagtaagtgacgag
aaccacaatgaaaaatgctgggagaaaaacgtgccggattctgtggaaaaccacaacatt
aactgtgaaagcttattgcaaaaccagcatggccttcctcagagccagctatgtgaaatg
tgtgactctgtcaccaaggaaggtctgagtttggaaactggaattccttctccactggaa
agaaaggtgttccctggaattcaactggaaatggatgatcctcccatggatataagccct
ttgggaaatcagtctgggatcctagagaccagcagcccccaccctgacagcaatatggcc
ttatttcatctccattatgaagttgacagaagaatgtcaggcactttacataccctgtca
gaaaactttattttggatgattgtggaaattgtgttacacttcctgagggacagcaaaag
aaaaacttcatggcgtatacttgtaaactgatggaattggcgaagacctgtggtaataag
aatgggcagctgtggtgtgaccattgcaacacgttgcatgataaatacctgtgctttgaa
aggtcccgcccgaaggtcagtgtggtctgctcaagcgagagtttttgcagggatggtttt
gctcacaatctacctgccaagacttttctgaactctttggaggatttctcgggtaattgt
gaagatgtagaggaagactttttcaaaaacaaaaaggagcggtccactttgttagtaaga
agattttgtaaaaatgacagagaagttaagaaatctgtgtatactgggacacgagcaatt
gtgagaactcttccttctggccacattggactgactgcttggagctatgtcgatcagaag
agaaacagtctcttgccaccttgtgggaaagtaatggaccctccatcaaccatgaacata
aggcagagcgggagccaacgactgtcagaaacccagtggcatttgatctacaatgcagta
aggcaaggagaagaaacagaagatacagttggatctcttctccattgcttcacaaagctc
ccagcctcagagccagcccttggaaggattagagatggtctgtgcttaaagcgatgtgtc
cgagacaccttatgtgagtaccgtgccacgctccaaagaacatccatttctcggtacgtc
accggctctctcctagaggcaaccacctctttgggagcaagaagtggccttctcagtact
tttggaggatctactggacgaatgatgctgaaagaacgccaaccaggcacctctatggcc
aattccagtgttctcccttcaagttcagctgggatcagcaaggaactgatcgatctccag
cccctcattcagttccccgaggaagtcgccagcatcctgacagagcaggagcagagcatt
taccgcaaggtcctgcccatggactacctttgtttcttaacccaggacctaggctcccct
gaatgccagaggtccctgccctgcctgaaagcatccatctcagcatcgattctcacctct
cagaatgatgagcacaacacccttgaagacctcttgatgagatttaatgaggtgagctcc
tgggtgacatggcttatcctcacggcgggctctatggaggagaagcgggaagtcttctcg
tatttggtgcatgtggccaaatgctgctggaacatgggcaactataatgctgtcatggag
ttcttggctggcctcaggtcaagaaaagttttaaaaatgtggcagttcatggaccagtct
gatattgagaccatgcggagcctgaaggatgccatggctcaacatgagtcttccgtggaa
tacaagaaggtggtgacccgggccctgcacatccctggctgcaaggtggttcccttctgt
ggggtgtttctgaaggagctctgtgaagtgcttgatggagcctccggccttctgaagctc
tgcccacggtataactcccaagaagaagctctagagtttgttgccgattatagcggacaa
gataatttcttacaacgagtgggacagaatggcctaaagaattcagagaaagagtccacg
gtcaacaacatctttcagatcatcaggagctgcagccgaagcttggagacggaggaggag
gatagctccagtgagggcaacagctctaggaaaaactccttgaaggagaaaacccagtgg
cagtttataattggagatttgctggattcagaaaatgacatctttgagcagtccaaagaa
tgtgaccctcatggatcagaggagtcacacaaagcctttgaccatgggacagagctcatc
ccttggtatgtgctgtccatccaggctgatgtgcaccagttcctgctgcagggagctacg
gtcatccactatgaccaggacacacacctctctgcccgctgctttctccagctgcagctt
gacaatagtaccttgacctggatgaagcctcccaccacctccccagctggtgcaagacct
aagcttggtatgcttagtaacatggctgagcctggcaagttcccatcactgggcagtgct
gggttgagcagcctgacagaggggatcctggatctgttttcagtgaaggctgtgtacatg
ggacaccctgccattgatatacacactgtatgtgttcagaacaaactgagcagcatgcct
ctgtcagagacgggggtgaccctgctctacgggcttcagacaactgacaatcgattattg
cactttgtggcaccaaaacacacagctaaaatgcttttcagtggattgctggaactcact
acagctgtgagaaagataaaaaagttccctgaccaaagacaacagtggcttcggaaacag
tatgtcagcctctatcaggaggatggtcggtatgaaggcccaactttggctcatgctgtg
gagttgtttggtggcagacgatggagcactagaaacgccagccctgggatatcagcaaag
aatgccgaaaagcccaacatgcagagaaacaataccctgggcataagcaccaccaagaag
aagaagaaaatgctcatgaggggagagagtggagaggcaactgatgacgagatggcaacc
cgcaaggccaaagtctacagagagtgtcgaagccgaagcggctctgatcctcaagacata
aacgaacaggaagagtcggaggtgaacgctaccactaactctcctaaccccctccattcc
agaagagcccactctctgaccacagctggatcccccaacttgtctgccgggatgtcatct
cccatcagttcgtggagcagcagcagctggcatgggcgaatcaaaggcggaatgaagggg
ttccagagcttcatggtctcagatagtaacatgagtttcgttgaatttgttgagctattc
aaatcattcagtgtaaggagccgcaaggacctgaaggacatctttgacatctactctgta
ccctgcaatcgatctggctctgaatcagcgccgctctacaccaacctgacaattgaggaa
aataccagtgaccttcagcctgacctcgatttgctcaccagaaacgtctcagacttgggg
ctgtttattaagagtaaacagcagctctctgacaaccagaggcagatatctgatgcaatt
gctgctgcaagtattgtgacaaatggcactggcatcgagagcacatccctgggcatattt
ggggttggcatactccaactcaacgacttcctggtgaactgccaaggtgaacactgcaca
tatgatgaaatcctcagcatcatccagaaattcgaacctagcatcagtatgtgtcatcag
ggcctaatgtcatttgaaggttttgcaaggtttctgatggataaagataattttgcctca
aaaaatgatgagtcacaggaaaacaagaaagaattgcaactacccctctcctactattac
attgaatcttcacacaatacctacctcacgggccatcagctcaaaggagagtcctcagta
gaactctacagccaggtcctcttgcaaggctgcaggagcatagagctggactgctgggat
ggagacgatggaatgcccattatttatcatggacatacactgaccaccaagatcccattc
aaggaggtggtggaagccattgatcgtagtgccttcatcacctctgacctaccaatcatc
atatccattgagaaccactgttcattgcctcagcaacgaaaaatggcagaaattttcaag
aatgtatttggagaaaagctggtggctaaattcttatttgagactgatttctcagatgat
ccaatgcttccctcacctgatcaacttaggaggaaaatacttcttaaaaataagaagcta
aaggcccatcagacaccagtggacatcttaaagcaaaaggctcatcagttagcatctatg
caagcacaggcttacaacggtgggaatgccaaccctctgcccaccaataacgaggaagaa
gaagatgaagaggatgaatatgattacgattatgaatccctttctgatgcagatgtcctt
actgcttcccctgctcctaagggtcaggaagacaacattctagaagacagacctgaaaac
aaatcatgtgctgacaagcttcagtttgagtataatgaagaaatcccaaaaagaataaag
aaagcagataactcttcttgcaacaaagggaaggtgtatgacatggagctgggagaagag
ttttatcttcctcagaataaaaaggaaagcagacagattgcaccagagctctctgacctt
gtcatctattgccaagcagtaaaattccccggcctgtcaactctaaattcatctggctct
agcagaggaaaagaaaggaaaagcaggaagtccatttttggcaacaatcctggcagaatg
agcccaggggagacagcatcacttaacaaaacatctggaaaaagttcctatgaagtaata
cggcaaacctgggaggaatcttccccactcaacccaaccacatccctcagcgctatcatc
aggactcccaaatgctatcatatctcatcactgaatgaaaatgccgccaaacgtctgtgt
cgtaggtattctcaaaaactgatccagcacacagccagtcagctgctgaggacgtaccct
gccgccacccggatcgactcatccaaccccaaccccctcatgttctggctccatgggata
cagctcgtggccctcaattaccagacagatgatctccctttacatttaaatgccacaatg
tttgaggcaaatggtggctgtggttatgttttaaagcccccagtcctgtgggataaaagt
tgtcccatgtatcagaagttttctccactggaaagagacctagataacatggaccctgcc
atctattctttaactattgtctctggccaaaatgtgtgccctagtaacagcacgggaagt
ccatgcattgaggttgacgtcctgggcatgcccctggacagctgccatttccggacgaag
cccatccatcgaaacactctgaaccccatgtggaatgaacagtttctgttccgggttcac
tttgaagatcttgtatttcttcgttttgcagttgtggaaaacaacagttcggcagtaaca
gctcagagaatcataccactcaaagctttaaaacgaggataccgacatcttcagctgcga
aacttccacaacgaagtcttggaaatctctagtttattcataaacagcagaagaatggaa
gaaaattcctctggtggtacaatgccagcctctttgatgtttaatactgaagagaggaaa
tgttctcagactcacagagtcacagtgcacgggatcccaggtccagagccctttgctgtt
ttcactataaatggaggcaccaaggcaaagcaacttctccaacaggttctggcaactgaa
caagacaccaaacttattgccatggactattttctgatggaagaaaaacattttatatct
aaagaaaaaaatgattgcaagaaacaaccattccagagagccgtgggtccagaagaagat
atcatgcagattctaagcagctggtttccagaggaaggctatgtaggcagaattgtctta
aaaccccaacaggaaaccctagaagagaaaagcattgtccaagatgacaaagaggtaatc
ttgagctcggaggagagtttctttgtccaagtgcatgatgtctctccagagcaacctcga
accgttatcaaagctccccgtgtcagtactgcacaggatgtcattcagcagaccttatgc
aaagccaaatattcctacagcatcctgagcaaccccaacccaggggactatgtacttttg
gaagaggtgatgaaagatgcgcccaacaagaagtcttctaacccaaagtcctcacagagg
atccttctggaccaagagtgtgtgtttcaagcccagagcaagtggaaaggtgcaggaaaa
ttcatcctcaagctaaaggagcaggtgcaggcatcccgagaagataaaagaaggggtatc
tcttttgcaagtgaactcaagaagctcaccaagtcaactaagcagtcccgaggactcata
ccacctcagcttgtggcctcagaaagtgtccaaagcaaggaggagaaacctatgggtgcc
ctgtcctccagtgacacaatggattaccgacagtga
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integrated database retrieval system
