Nannospalax galili (Upper Galilee mountains blind mole rat): 103750732
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Entry
103750732 CDS
T03372
Symbol
Pak4
Name
(RefSeq) p21 (RAC1) activated kinase 4
KO
K05734
p21-activated kinase 4 [EC:
2.7.11.1
]
Organism
ngi
Nannospalax galili (Upper Galilee mountains blind mole rat)
Pathway
ngi04012
ErbB signaling pathway
ngi04014
Ras signaling pathway
ngi04360
Axon guidance
ngi04510
Focal adhesion
ngi04660
T cell receptor signaling pathway
ngi04810
Regulation of actin cytoskeleton
ngi05170
Human immunodeficiency virus 1 infection
ngi05206
MicroRNAs in cancer
ngi05211
Renal cell carcinoma
Brite
KEGG Orthology (KO) [BR:
ngi00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
103750732 (Pak4)
04014 Ras signaling pathway
103750732 (Pak4)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
103750732 (Pak4)
09142 Cell motility
04810 Regulation of actin cytoskeleton
103750732 (Pak4)
09150 Organismal Systems
09151 Immune system
04660 T cell receptor signaling pathway
103750732 (Pak4)
09158 Development and regeneration
04360 Axon guidance
103750732 (Pak4)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
103750732 (Pak4)
09162 Cancer: specific types
05211 Renal cell carcinoma
103750732 (Pak4)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
103750732 (Pak4)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ngi01001
]
103750732 (Pak4)
Enzymes [BR:
ngi01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
103750732 (Pak4)
Protein kinases [BR:
ngi01001
]
Serine/threonine kinases: STE group
STE20 family
103750732 (Pak4)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
PBD
ABC1
Kinase-like
Pkinase_fungal
hnRNP_Q_AcD
RIO1
KIND
Motif
Other DBs
NCBI-GeneID:
103750732
NCBI-ProteinID:
XP_008852167
UniProt:
A0A8C6RE78
LinkDB
All DBs
Position
Un
AA seq
592 aa
AA seq
DB search
MFGKRKKRVEISAPSNFEHRVHTGFDQHEQKFTGLPRQWQSLIEESARRPKPLIDPACIT
SIQPGAPKTIVRGSKGAKDGALTLLLDEFENMSVTRSNSLRRDSPPPPARAHQENGVPEE
RVTQARVAPEKAGGRDRATGHSEAGGGSGDRRRVGPEKRPKSSREGLGGPQEASRDKRPL
SGPDVGTPQPASLASGVKLAAGRPFNTYPRADTDHPARGAQGESHNMAPNGPSAGGHTAP
QSSSSRPPTRAHGAPSRGMLGPHASEPQLAPPARALAAPAAPPAPGPPGPRSPQREPQRV
SHEQFRAALQLVVDPGDPRSYLDNFIKIGEGSTGIVCIATVRSSGKLVAVKKMDLRKQQR
RELLFNEVVIMRDYRHENVVEMYNSYLVGDELWVVMEFLEGGALTDIVTHTRMNEEQIAA
VCLAVLQALSVLHAQGVIHRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVPRRKSLVGTP
YWMAPELISRLPYGPEVDIWSLGVMVIEMVDGEPPYFNEPPLKAMKMIRDNLPPRLKNLH
KASPSLKGFLDRLLVRDPAQRATAAELLKHPFLTKAGPPASIVPLMRQHRTR
NT seq
1779 nt
NT seq
+upstream
nt +downstream
nt
atgtttgggaaaaggaagaagcgggtcgagatctcggccccatccaacttcgagcaccga
gtgcacacgggcttcgaccagcatgagcagaagttcacagggctgccccgccaatggcag
agcctgattgaggagtcggcccgccggcccaagcctctcatagacccagcctgcatcacc
tccatccagcctggagcccctaagaccatcgtgcggggcagcaaaggtgccaaggatggt
gccctcacactgctgctcgacgagtttgagaacatgtcggtgacacgctccaactccctg
cgcagagacagcccgccaccgcctgcccgtgctcaccaagagaatggggttccagaggag
cgggtcacccaggccagagtggcccccgagaaggcgggaggccgagaccgggccacgggc
cacagcgaggcaggtggtggcagtggtgacaggcggcgggtagggccagagaagaggccc
aagtcttccagggagggcctgggaggaccccaggaggcctcccgagataagcgccccctc
tctgggcctgatgtcggcacgccccagcctgccagtctggccagcggggtgaaactagca
gctggcaggccctttaacacatacccacgggctgatacggaccaccctgcccgaggtgcc
cagggggaatcacacaatatggcccctaatgggccatcagctgggggacacactgccccc
cagtcctcttcctctcggcctcccacccgagcccacggtgcccccagccgtggaatgctg
ggtccccatgcctcagagccccagctggcccctccagcccgtgccctcgctgctcctgct
gcaccccctgcccctgggccccctgggcctcgctcacctcagcgggagccccagcgagtg
tcccatgagcagttccgggctgccctgcaattggtggtggacccaggggacccacgttcc
tatctagataacttcatcaagattggtgaggggtccacaggcatcgtgtgcatagctaca
gtgcgtagctcaggcaagctggtggccgtcaagaagatggacctgcgcaagcagcagagg
cgcgagttgctctttaatgaggtggtgatcatgcgtgactatcggcacgagaacgtagta
gagatgtacaacagctacctggtgggggacgagctctgggtggtgatggagttcttggaa
ggaggtgccctcaccgacatcgttacccacacaaggatgaatgaggagcagattgccgct
gtgtgcctggctgtgctgcaggcactgtccgtcctccatgcccagggcgtcatccaccgt
gacatcaagagtgactccatcctgctgactcacgatggccgggtgaagctgtccgacttt
gggttctgcgcccaggtgagcaaggaggtacctcggaggaagtcactggttggcacaccg
tactggatggccccagaactcatctcccgccttccctacgggccggaggtggacatctgg
tcactgggcgtaatggtgatcgagatggtggatggggagcctccctacttcaatgagcca
cccctcaaagccatgaagatgattcgagacaacctgcctccccgactgaagaacctgcac
aaggcctcgccatctctgaaaggcttcctggaccgcctgctggttcgggacccagcccag
cgggccaccgcggcagagctgctaaagcacccgttccttaccaaggcaggaccccctgcc
agcatcgtgcccctcatgcgccagcaccgcaccagatga
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