Nannospalax galili (Upper Galilee mountains blind mole rat): 103752265
Help
Entry
103752265 CDS
T03372
Symbol
Pde8b
Name
(RefSeq) phosphodiesterase 8B
KO
K18437
high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:
3.1.4.53
]
Organism
ngi
Nannospalax galili (Upper Galilee mountains blind mole rat)
Pathway
ngi00230
Purine metabolism
ngi01100
Metabolic pathways
ngi04927
Cortisol synthesis and secretion
ngi04934
Cushing syndrome
ngi05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
ngi00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
103752265 (Pde8b)
09150 Organismal Systems
09152 Endocrine system
04927 Cortisol synthesis and secretion
103752265 (Pde8b)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
103752265 (Pde8b)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
103752265 (Pde8b)
Enzymes [BR:
ngi01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
103752265 (Pde8b)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PDEase_I
PDE8A_N
PDE8
PAS_9
PAS
PAS_3
PAS_4
PAS_8
DUF4194
DHH
Motif
Other DBs
NCBI-GeneID:
103752265
NCBI-ProteinID:
XP_008854207
LinkDB
All DBs
Position
Un
AA seq
885 aa
AA seq
DB search
MGCAPSIHVSQSGVIYCRDSDESNSPRQSSSVSQGPAAPLHGLFVQTDAADAMPPSRAPG
PPGAVRVRRARAELGSGSSAGSSGPAATTCRGRRRHCCSSAEAETQTSYTSVKQVSSAEV
RIGPMRLTQDPIQVLLIFAKEDSQSDGFWWACDRAGYRCNIARTPESALECFLDKHHEII
VIDHRQTRNFDAEAVCRSIRATNPSEHTVILAVVSQASDDHEEASVLPLLHAGFNRRFME
NSSVIACYNELIQIEHGEVRSQFKLRACNSVFTALDHCHEAIEITSDDHVIQYVNPAFER
MMGYHKGELLGKELADLPKSDKNRADLLDTINTCIKKGKEWQGVYYARRKSGDSIQQHVK
ITPVIGQGGKIRHFVSLKKLCCTTDNNKQIHRIHRDSGDNSQTEPHSFRYKSRRKESIDV
KSISSRGSDAPSLQNRRYPSMARIHSMTIEAPITKVINIINAAQENSPVTVAEALDRVLE
ILRTTELYSPQLGTKDEDPHTSDLVGGLMTDGLRRLSGNEYVFTKNVHQSHSHLAMPITI
NDVPPSIAQLLDNEESWDFNIFELEAVTHKRPLVYLGLKVFSRFGVCEFLNCTETTLRAW
LQVIEANYHSSNAYHNSTHAADVLHATAFFLGKERVKGSLDQLDEVAALIAATVHDVDHP
GRTNSFLCNAGSELAVLYNDTAVLESHHTALAFQLTVKDTKCNIFKNIDRNHYRTLRQAI
IDMVLATEMTKHFEHVNKFVNSINKPLAAESEGSDCECNPTGKNFPENQILIKRMMIKCA
DVANPCRPLDLCIEWAGRISEEYFAQTDEEKRQGLPVVMPVFDRNTCSIPKSQISFIDYF
ITDMFDAWDAFAHLPALMQHLADNYKHWKTLDDLKCKSLRLPSDS
NT seq
2658 nt
NT seq
+upstream
nt +downstream
nt
atgggctgcgcccccagcatccatgtctcgcagagcggcgtgatctactgccgggactcg
gatgagtccaactcgccccgccagagcagcagcgtgtcgcagggccccgcggcgcccctg
cacggcctcttcgtgcagaccgacgccgccgacgccatgcccccgagccgcgcgcccgga
cccccgggtgccgtccgggtccgcagggcccgggccgagctgggcagcggcagcagcgcg
ggctcctcgggccccgcggcgaccacctgcaggggccggaggcgccactgctgcagcagc
gcggaggccgagacccagaccagctacaccagcgtcaagcaggtgtcgtcggcagaggta
cgcattgggcccatgagactgacgcaggaccctatccaggttttgctaatctttgcaaaa
gaagatagccagagtgatggcttctggtgggcctgcgacagagccggttacagatgtaac
attgctcggactccagagtcagcccttgaatgctttctggacaaacatcatgaaattatt
gtgattgatcacaggcaaacccgaaactttgatgcagaagcagtgtgcaggtcgatccgg
gctacgaacccctcggagcacacagtaatcctcgctgtggtgtcacaagcatctgatgac
catgaagaggcctcagttcttcctcttctccatgcaggcttcaaccggagatttatggag
aatagcagcgtaattgcttgctataatgaactgattcaaatagaacatggggaagttcgc
tcacagttcaaattacgggcctgcaattcagtgtttacagcattagaccactgtcacgaa
gccatagaaataacaagtgatgaccacgtgattcagtatgtcaatcctgcctttgagagg
atgatgggctaccacaaaggggaacttctggggaaagaacttgccgacctacctaagagc
gacaagaaccgggcagacctcctggacaccatcaatacgtgcatcaagaagggaaaggag
tggcagggggtttactatgccagacggaaatccggggacagcatccaacagcacgtgaag
atcaccccagtgattggccaaggagggaaaattaggcattttgtctccctcaagaagctg
tgttgtaccactgacaataataagcagattcacagaattcatcgtgattcaggagacaac
tctcagacagagccacattcgttcagatacaagagcaggaggaaagagtccattgatgtg
aaatcaatatcttctcgaggcagtgatgcaccaagcctacaaaatcgccgctatccctcc
atggcaagaatccactccatgaccatcgaggctcccatcacaaaggttataaatataatc
aatgcagcccaagaaaacagcccagtcacagtagcagaagccttggacagagttctagaa
attttacggaccacagaactgtactcccctcagctgggaaccaaagacgaagatcctcat
accagcgatcttgttggaggcctgatgactgatggtttgagaagactgtcagggaatgag
tatgtgtttacaaagaatgtgcaccagagtcacagtcaccttgcgatgcccataaccatc
aatgatgtcccccctagtatcgcccaattacttgacaatgaggaaagttgggacttcaac
atctttgaattggaagcagtgacacataaaaggcctttggtttacctgggcttaaaggtc
ttctctcggtttggagtatgtgaatttctaaactgtactgaaaccactcttcgagcttgg
ctgcaagtgattgaagccaactaccactcctccaatgcctaccataattccacccatgct
gccgatgtcctgcacgccacagctttcttccttggaaaggaaagagtgaagggaagcctc
gatcagctggatgaggtggctgccctgattgctgccacagtccatgatgtggatcaccct
ggaaggaccaactctttcctgtgcaatgcaggcagtgagcttgctgtgctctacaatgac
accgcagtcttggagagtcaccacacagccctggccttccagctcacggtcaaggacact
aaatgcaacattttcaagaatattgacaggaaccattatcgaacactgcgccaggctatt
attgacatggttttggccacagagatgacaaaacactttgaacatgtgaacaaatttgtg
aacagcatcaacaagccattggcagctgagagtgaaggcagtgactgtgaatgcaacccc
actgggaagaattttcctgaaaaccaaatcctgatcaagcgcatgatgattaaatgtgct
gatgtggccaatccatgccggcccttggacctgtgcattgaatgggctggaaggatctct
gaggagtattttgcacagactgatgaagagaagagacagggactacctgtggtgatgcca
gtgtttgaccgcaatacctgcagcatccctaagtcccagatctccttcattgactacttc
ataacagacatgtttgatgcctgggatgcctttgcacatctgccagcactgatgcagcat
ttggctgataactacaagcactggaagacattagatgacctcaagtgcaaaagtctgaga
ctcccatctgacagctaa
DBGET
integrated database retrieval system
