KEGG   Nannospalax galili (Upper Galilee mountains blind mole rat): 15088433
Entry
15088433          CDS       T03372                                 
Symbol
ND5
Name
(RefSeq) NADH dehydrogenase subunit 5
  KO
K03883  NADH-ubiquinone oxidoreductase chain 5 [EC:7.1.1.2]
Organism
ngi  Nannospalax galili (Upper Galilee mountains blind mole rat)
Pathway
ngi00190  Oxidative phosphorylation
ngi01100  Metabolic pathways
ngi04714  Thermogenesis
ngi04723  Retrograde endocannabinoid signaling
ngi05010  Alzheimer disease
ngi05012  Parkinson disease
ngi05014  Amyotrophic lateral sclerosis
ngi05016  Huntington disease
ngi05020  Prion disease
ngi05022  Pathways of neurodegeneration - multiple diseases
ngi05208  Chemical carcinogenesis - reactive oxygen species
ngi05415  Diabetic cardiomyopathy
Module
ngi_M00142  NADH:ubiquinone oxidoreductase, mitochondria
Brite
KEGG Orthology (KO) [BR:ngi00001]
 09100 Metabolism
  09102 Energy metabolism
   00190 Oxidative phosphorylation
    15088433 (ND5)
 09150 Organismal Systems
  09156 Nervous system
   04723 Retrograde endocannabinoid signaling
    15088433 (ND5)
  09159 Environmental adaptation
   04714 Thermogenesis
    15088433 (ND5)
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    15088433 (ND5)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    15088433 (ND5)
   05012 Parkinson disease
    15088433 (ND5)
   05014 Amyotrophic lateral sclerosis
    15088433 (ND5)
   05016 Huntington disease
    15088433 (ND5)
   05020 Prion disease
    15088433 (ND5)
   05022 Pathways of neurodegeneration - multiple diseases
    15088433 (ND5)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    15088433 (ND5)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03029 Mitochondrial biogenesis [BR:ngi03029]
    15088433 (ND5)
Enzymes [BR:ngi01000]
 7. Translocases
  7.1  Catalysing the translocation of protons
   7.1.1  Linked to oxidoreductase reactions
    7.1.1.2  NADH:ubiquinone reductase (H+-translocating)
     15088433 (ND5)
Mitochondrial biogenesis [BR:ngi03029]
 Mitochondrial DNA transcription, translation, and replication factors
  Mitochondrial DNA-encoded proteins
   Mitochondrial respiratory chain complex I
    15088433 (ND5)
SSDB
Motif
Pfam: Proton_antipo_M NADH5_C Proton_antipo_N
Other DBs
NCBI-GeneID: 15088433
NCBI-ProteinID: YP_007626768
UniProt: G5D5I4
LinkDB
Position
MT
AA seq 608 aa
MNINVSMNLLILTTLTTPLLLSLTSKYNSNSYPKHVINSIKLSFLFSLIPLLTFLNNNNE
LITSNWHWMTINSIKLVMSFKFDYFSYLFIPVALFVTWSITEFSSWYMHSDPNLNRFMKY
LLMFLMTMIILVSANNLFQLFIGWEGVGIMSFLLIGWWFGRTDANTAALQAILYNRIGDI
GLILSMAWFTIHTNSWELQQIFIFNTNTDILPLLGILLAATGKSAQFGLHPWLPSAMEGP
TPVSALLHSSTMVVAGVFLMIRFYPLTQNNQTILTLTLCLGAMTTLFTAMCALTQNDIKK
IVAFSTSSQLGLMFVTLGINQPHLAFLHICTHAFFKAMLFMCSGSIIHNLNNEQDIRKMG
GLFKSMPFTSSCLTIGSLALTGMPFLTGFYSKDLIIETLNTSNTNAWALLVTLIATSMTA
VYSTRIIFFVVMSKPHFTPTITMNENNPQLINPINRLALGSILAGFMITSNLPPTNIPTM
TMPLSLKLMAITISILGFTVAMDLNNMTSTLKHKSPTPTHKFTTLLGYFPSIIHRLLPVK
SLTMSQNMASNLMDLIWLEKAIPKTIANTQMTASIITSNQKGLIKLYSLSFLMNITIISL
LTLTYYLE
NT seq 1827 nt   +upstreamnt  +downstreamnt
attaatatcaacgtctcaataaatttactaatcctaacaaccctaacaacccccttactt
ctatcactaactagcaaatataactcaaacagctaccctaaacacgtaattaactcaatt
aaattatcgtttctatttagcctaatccctctactcacatttctcaacaacaataatgaa
ctcatcacatcaaactgacactgaataacaatcaactcaattaaattagttataagcttt
aaatttgactatttctcttatctatttattccagtagcattatttgtaacatggtcaatc
acggaattttcttcatgatatatacactccgacccaaacctaaaccgattcataaaatac
ttactaatattcttaataaccataattatcctagtatcagctaacaacctatttcaacta
ttcattggatgagaaggagtaggaatcatatcatttttactaattggttggtgattcgga
cgaacagatgccaacaccgcagctctacaagccattttatacaatcgcatcggagatatc
ggcctaattctatctatagcctgatttacaatccacacaaactcatgagagctacaacaa
atcttcatcttcaacacgaacactgacattctaccattattaggtattctactagccgca
acaggcaaatcagcccaatttggactccacccatgacttccctcagctatagaagggcca
acaccagtatcagctctattacactcaagtacaatagttgtagccggagtattcctaata
atccgattctacccactaacacaaaacaaccaaactatcctaactttaacactatgccta
ggagcaataaccacactatttaccgcaatatgtgctcttacacaaaacgacatcaaaaaa
atcgtagcattctccacctcaagccaacttggcttaatatttgttaccctagggattaat
caaccacacctagcattccttcacatctgtacccacgccttcttcaaagccatactattc
atatgctccggatcaatcatccacaacctaaataatgaacaagacatccgaaaaatagga
ggactgtttaaatccataccattcacctcatcctgcttaaccatcggaagcctcgcactg
acagggataccattcctaacaggtttctactcaaaagacttaatcatcgaaacccttaat
acgtctaataccaacgcctgagccttactagtcacactaatcgccacctcaataactgct
gtatacagcacacgaatcatcttcttcgttgtaatatctaaaccacacttcaccccaaca
atcacaataaacgaaaataaccctcaacttattaaccctattaaccgcctagccctgggg
agtatcctagcaggatttataattacctcaaatctcccaccaactaatattcccacaata
acaataccactatcactaaaattaatagccattacaatttctattttagggtttacagtc
gccatagacctaaacaacataacctcaacacttaaacacaaatcacctacccccacacac
aaattcaccacactgctaggatactttccatcaattatccaccgcctattaccagtcaaa
agcctaactataagccaaaacatagcatcaaacctaatagacctaatttgactagaaaaa
gctatcccaaaaacaattgccaacacacaaataactgcttccatcattacatcaaaccaa
aaaggacttatcaaactctactcactatcattcctaataaatattaccattatctcacta
ctcaccctaacctattacctcgagtaa

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