Neisseria gonorrhoeae NCCP11945: NGK_1970
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Entry
NGK_1970 CDS
T00728
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
ngk
Neisseria gonorrhoeae NCCP11945
Pathway
ngk00230
Purine metabolism
ngk01100
Metabolic pathways
ngk01110
Biosynthesis of secondary metabolites
Module
ngk_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
ngk00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
NGK_1970
Enzymes [BR:
ngk01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
NGK_1970
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Paralog
Gene cluster
GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
Motif
Other DBs
NCBI-ProteinID:
ACF30588
UniProt:
B4RJC3
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Position
1628929..1632885
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AA seq
1318 aa
AA seq
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MSVVLPLRGVTALSDFRVEKLLQKAAALGLPEVKLSSEFWYFAGSEKALDAATVEKLQAL
LAAQSVEQTPEAREGLHLFLVTPRLGTISPWASKATNIAENCGLAGIERIERGMAVWLEG
ALTDEQKQQWAALLHDRMTESVLPDFQTASKLFHHLKSETFSTVDVLGGGKEALVKANTE
TGLALSADEIDYLVENYQALQRNPSDVELMMFAQANSEHCRHKIFNADFILNGEKQPKSL
FGMIRDTHNAHPEGTVVAYKDNSSVIKGAKIERFYPNAAENQGYRFHEEDTHIIMKVETH
NHPTAIAPFAGAATGAGGEIRDEGATGKGSRPKAGLTGFTVSNLNIPDLKQPWEQDYGKP
EHISSPLDIMIEGPIGGAAFNNEFGRPNLLGYFRTFEEKFDGQVRGYHKPIMIAGGLGSI
QAQQTHKDEIPEGALLIQLGGPGMLIGLGGGAASSMDTGTNDASLDFNSVQRGNPEIERR
AQEVIDRCWQLGDQNPIISIHDVGAGGLSNAFPELVNDAGRGAVFELREVPLEEHGLTPL
QIWCNESQERYVLSILEKDLDTFRAICERERCPFAVVGTATDDGHLKVRDDLFSNNPVDL
PLNVLLGKPPKTTRTDKTVTPSKKPFHAGDIDITEAAYRVLRLPAVAAKNFLITIGDRSV
GGMTHRDQMVGKYQTPVADCAVTMMGFNTYRGEAMSMGEKPAVALFDAPASGRMCVGEAI
TNIAAVNIGDIGNIKLSANWMAACGNEGEDEKLYRTVEAVSKACQALDLSIPVGKDSLSM
KTVWQDGEEKKSVVSPLSLIISAFAPVKDVRKTVTPELKNVEGSVLLFIDLGFGKARMGG
SAFGQVYNNMSGDAPDLDDAGRLKAFYSVIQQLVAEDKLLAYHDRSDGGLFATLAEMAFA
ARCGISADIDCLMDKFLPIHLPDFQGDPAEDLSDELYNHAAIKILFNEELGAVIQIRQKD
RDYVDAAFETAGLTDAVSRIGSPDFDNEFISFFGYGYFLEQNRADLQRAWQETSHAIQRL
RDNPACADSEFALIGDNERSALFADVKFDVNEDIAAPFINSGAKPKIAILREQGVNGQIE
MAAAFTRAGFDAYDVHMSDLMAGRFRLADFKMLAACGGFSYGDVLGAGEGWAKSILFHPA
LRDQFAAFFADPNTLTLGVCNGCQMVSNLAEIIPGAETWPKFKRNLSEQFEARLNMVHVP
KSASLILNEMQDSSLPVVVSHGEGRADFALHGGNISADLGIALQYVDGQNQVTQTYPLNP
NGSPQGIAGITNADGRVTIMMPHPERVYRAAQMSRKPEGWTELSGWYRLFAGARKALG
NT seq
3957 nt
NT seq
+upstream
nt +downstream
nt
atgtctgttgttttgcccttgcgcggcgttaccgccctttccgatttccgtgtcgaaaaa
ctcttgcaaaaagccgccgcactcggcctgcccgaagtcaaattaagcagcgaattttgg
tatttcgccggcagcgagaaagcacttgatgccgcgactgtcgaaaaactgcaagccttg
ttggcggcgcaaagcgttgaacaaacgcccgaagcgcgcgagggtttgcatttgtttttg
gtaacgccccgtttgggtacgatttcgccgtgggcttccaaggcgaccaatatcgcggaa
aactgcggtttggcaggcatcgaacgcatcgagcgcggtatggcggtgtggctggaaggt
gcgcttaccgatgaacagaaacagcaatgggcggcgttgctgcacgaccgcatgaccgaa
tccgtgctgcccgattttcagacggcatccaaattattccaccatctcaaatccgaaacc
ttctccaccgtcgatgttttgggcggcggtaaagaggctttggtcaaagccaataccgaa
acgggtttggcactctccgccgacgaaatcgattatctggttgaaaactatcaggctttg
cagcgcaatccgtccgatgtggagctgatgatgttcgcgcaggcaaacagcgaacactgc
cgccacaaaatcttcaacgccgatttcatcctcaacggcgaaaaacaaccgaaatccctg
ttcggcatgatacgcgacacgcacaacgcgcatcccgaaggtacggtcgtcgcctataaa
gacaattcgtccgtgatcaaaggcgcgaaaatcgagcgtttctatccgaatgcagcggaa
aaccaaggctaccgtttccacgaggaagacacccacatcatcatgaaagtggaaacgcac
aaccacccgaccgccatcgcgccgtttgcgggcgcggcaacaggcgcgggcggcgaaatc
cgcgacgaaggtgcgacgggcaaaggttcgcgtccgaaagcgggcttgaccggctttacc
gtgtccaacctcaacatccccgacctcaaacagccgtgggaacaagactacggcaagccg
gaacacatttcctcgccgttggacatcatgattgaaggcccgattggcggtgcggcgttc
aacaacgaattcggccgcccgaacctcttgggctacttccgcacctttgaagaaaaattt
gacggtcaggttcgcggctaccacaaaccgattatgattgccggcggtttgggcagcatt
caggcgcagcagacgcacaaagacgaaatccccgaaggcgcactgctgatccaactgggc
ggcccgggcatgctcatcggcttgggcggcggtgcggcttcttcgatggataccggtaca
aatgatgcgtctttggacttcaactccgtacaacgcggcaaccctgaaatcgaacgccgc
gcgcaggaagtcatcgaccgctgctggcagctcggcgaccaaaacccgattatctccatc
cacgacgtgggcgcgggcggcttgtccaacgctttccctgaattggtcaacgatgccgga
cgcggcgcggtattcgagctgcgcgaagtgccgttggaagaacacggtttaacgcctttg
caaatctggtgtaacgaatcgcaagagcgttatgtcttgtcgattttggaaaaagatttg
gacaccttccgcgccatctgcgaacgcgaacgctgcccgtttgccgtagtcggcacggcg
accgacgacggtcatttgaaagtgcgcgacgatttgttctccaacaaccccgtcgatttg
ccgctgaacgtcttgctcggcaaaccgcccaaaaccacgcgtaccgacaaaacggttacg
ccgtccaaaaaaccgtttcacgcgggcgatatcgacatcaccgaagccgcctaccgcgtt
ttgcgcctgcctgccgtagccgccaaaaacttcctgattaccatcggcgaccgcagcgtc
ggcggcatgacccaccgcgaccaaatggtcggcaaataccaaacccccgtagccgactgc
gccgttaccatgatgggcttcaacacctatcgcggcgaagcgatgtctatgggcgaaaaa
ccggccgtcgccctgtttgacgcgcccgcctcgggcagaatgtgcgtcggcgaagccatc
accaacatcgcggcagtcaacatcggcgacatcggcaacatcaaactttccgccaactgg
atggcggcgtgcggcaacgaaggcgaagacgaaaaactctaccgcaccgtcgaagccgtt
tctaaagcctgccaggcattggatttgagcattcccgtaggtaaagacagcctgtcgatg
aaaaccgtgtggcaggacggcgaagagaaaaaatccgtggtttcgccgttgagcctgatt
atttccgcgttcgcgcctgttaaagacgtgcgaaaaaccgttacgcccgaattgaaaaac
gtcgaaggcagcgtattgctgtttatcgatttgggcttcggcaaagcgcgcatgggcggc
tcggcgttcggtcaggtgtacaacaacatgagcggcgacgcgcccgatttggacgatgca
ggccgtctgaaagcgttttacagcgtaattcaacagcttgtcgccgaagacaaacttttg
gcgtatcacgaccgcagcgacggcggtttgtttgcgacgctggcggaaatggcgtttgcg
gcacggtgcggtattagtgccgatatagattgcctgatggataaattcctgccgattcat
ctcccggattttcaaggcgaccctgccgaagacttatctgacgaactttataatcatgcc
gccattaaaatcttattcaatgaagaattaggcgcggttatccaaatccgccaaaaagat
agggattatgttgatgcggcatttgaaacggccggcttaaccgatgcggtcagccggatt
ggctctcctgattttgacaatgagtttatttctttctttggttacggttatttcttggaa
caaaaccgcgccgacctgcaacgcgcgtggcaggaaaccagccacgccatccaacgcctg
cgcgacaaccctgcctgcgccgacagcgagttcgccctgattggcgacaacgaacgcagc
gcattgtttgccgacgtgaagttcgacgtgaacgaagacatcgccgcgccgtttatcaac
agtggcgcgaaacctaaaatcgccatcctgcgcgaacagggcgtaaacgggcaaatcgaa
atggccgccgccttcacccgcgccggattcgatgcctacgacgtgcatatgtccgacctg
atggctggccgcttccgccttgccgacttcaaaatgctggcggcgtgcggcggcttcagc
tacggcgacgtactcggcgcgggtgaaggctgggcgaaatccatcctgttccaccctgcc
ttgcgcgaccaattcgccgccttctttgccgatccgaacacgctgacattgggcgtgtgc
aacggctgccaaatggtcagcaaccttgccgaaattatcccgggcgcagaaacatggccg
aagttcaaacgcaacctgagcgagcagtttgaagcgcgcctgaatatggttcacgtcccc
aaatcagcgtcgctgattttgaacgaaatgcaagactccagcctgcctgtcgtggtcagc
cacggcgaaggccgcgccgacttcgcgcttcacggcggcaatatttccgccgatttgggc
atcgcgctgcaatatgtggacggtcaaaaccaggttacccaaacctatccgctcaacccc
aacggctcgccgcagggcatcgccggcattaccaacgccgacggccgcgttaccattatg
atgccccaccccgaacgcgtgtaccgtgccgcacaaatgagccggaaaccggaaggctgg
acggaactgtccggctggtaccgcctctttgccggcgcacgtaaagccttgggctaa
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