Neisseria gonorrhoeae FA 1090: NGO_1539
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Entry
NGO_1539 CDS
T00237
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
ngo
Neisseria gonorrhoeae FA 1090
Pathway
ngo00300
Lysine biosynthesis
ngo00550
Peptidoglycan biosynthesis
ngo01100
Metabolic pathways
ngo01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
ngo00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
NGO_1539
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
NGO_1539
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
NGO_1539
Enzymes [BR:
ngo01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
NGO_1539
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
AAW90175
UniProt:
Q5F6L2
LinkDB
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Position
complement(1510761..1512119)
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AA seq
452 aa
AA seq
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MKPLDLNFICQALKLPMPSENKPVSRIVTDSRDIREGDVFFALAGGRFDAHDFVGGVLSA
GAAAVVVSREDCAALGGALKVDDTLAALQTLAKAWRDNVNPFVFGITGSGGKTTVKEMLA
AVLRRRFGDDAVSATAGNFNNHIGLPLTLLKLNEKHRYAVIEMGMNHFGELAVLTQIAKP
DAALVNNALRAHVGCGFDGVGDIAKAKSEIYAGLCSDGMALIPQEDANMAVFKTATFNLN
TCTFGVDSGDVRAENIVLKPLSCEFDLVCGDERTAVVLPVPGRHNVHNAAAAAALALAAG
LSLNDVAEGLQGFSNIKGRLNVKAGIKGATLIDDTYNANPDSMKAAVDVLARMPAPRIFV
MGDMGELGEDEAAAMHAEVGAYARDQGIEAAYFVGDNSVEAAEKFGADGLWFAAKDPLIQ
VLSHDLPERATVLVKGSRFMQMEEVVEALEDK
NT seq
1359 nt
NT seq
+upstream
nt +downstream
nt
atgaaaccactggacctaaatttcatctgccaagccctcaagcttccgatgccgtctgaa
aacaaacccgtgtcgcgcatcgtaaccgacagccgcgatattcgggaaggcgatgtgttt
ttcgcattggcgggcgggcggtttgacgcgcatgattttgttggaggcgtattgtctgcg
ggcgcggcggcggttgtggtttcgcgcgaagattgcgcggctttgggcggcgcgttgaaa
gtcgatgacacgcttgccgcgttgcaaacgttggcgaaggcgtggcgcgataatgtgaac
ccgtttgtgttcggcattaccggttcgggcggcaagacgacggtgaaggagatgctggct
gcggtattgcgccgccgtttcggcgatgatgccgtttcggcgacggcaggcaacttcaac
aaccacatcggattgccgctgactttattgaaattaaacgaaaaacaccgctatgccgtg
attgaaatgggcatgaaccattttggcgaactggcggttttaacgcaaatcgccaaaccc
gatgccgctttggtcaacaacgccctgcgcgcccatgtcggatgcggtttcgacggagtg
ggcgatattgccaaagcgaaaagcgagatttatgcaggcttatgttcagacggcatggca
ctgattcctcaagaagatgccaatatggctgtcttcaaaacggcaacgtttaatttgaat
acgtgcactttcggcgtcgatagcggcgatgtccgcgcggaaaatatcgtgctgaaacct
ttgtcgtgcgaatttgatttggtgtgcggcgacgagcgcactgccgtggtgctgcctgtt
cccggccgccacaatgtccacaacgccgccgctgccgccgcgctggctttggctgccggt
ttgagtttgaacgatgtggcggaaggtttgcaaggcttcagcaacatcaaaggccgtctg
aacgtcaaagccggcatcaagggcgcaaccctgattgacgatacttataatgcgaatccc
gacagtatgaaagccgcggttgacgtgttggcgcgtatgcctgcgccgcgcattttcgtg
atgggcgatatgggcgaactgggcgaggacgaagccgccgccatgcacgccgaagtcggc
gcgtacgcccgcgaccaaggcatcgaagcggcttattttgtcggcgacaacagcgtcgaa
gcggcggaaaaatttggcgcggacggtttgtggttcgccgccaaagacccgttgattcaa
gtgttgagccacgatttgcccgaacgcgccaccgtgttggtgaaaggttcgcgctttatg
cagatggaagaagtggtcgaggcattggaggataagtga
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