KEGG   Naegleria gruberi: NAEGRDRAFT_54929
Entry
NAEGRDRAFT_54929  CDS       T01241                                 
Name
(RefSeq) 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) reductase
  KO
K00021  hydroxymethylglutaryl-CoA reductase (NADPH) [EC:1.1.1.34]
Organism
ngr  Naegleria gruberi
Pathway
ngr00900  Terpenoid backbone biosynthesis
ngr01100  Metabolic pathways
ngr01110  Biosynthesis of secondary metabolites
Module
ngr_M00095  C5 isoprenoid biosynthesis, mevalonate pathway
Brite
KEGG Orthology (KO) [BR:ngr00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00900 Terpenoid backbone biosynthesis
    NAEGRDRAFT_54929
Enzymes [BR:ngr01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.34  hydroxymethylglutaryl-CoA reductase (NADPH)
     NAEGRDRAFT_54929
SSDB
Motif
Pfam: HMG-CoA_red
Other DBs
NCBI-GeneID: 8861105
NCBI-ProteinID: XP_002668160
JGI: Naegr1_54929
UniProt: D2W686
LinkDB
AA seq 320 aa
MATVEGCLVASTHRGCKALSSSFEGGVNSVILSDGMTRGPVVQFANTKRCNELKQFIDNP
ENFKELCRVFNSDSRFARLLEVKVGIAGRKAFLRFKCRTGDAMGMNMISKATQKALKFLK
NEHFQDMDILSLSGNYCTDKKPSAMNWIEGRGKSVVVDATIPKDVVKNVLKTTVDEIVSL
NISKNLIGSAMAGSVGGFNAHAANIVTAIFLATGQDAAQNVESSNCMTIMEKTDNGDLYV
SVTMPSIEVGTVGGGTHLDAQKTCLKIIGVAGANQENPGQNAQTLAKCVASTVMAGELSL
MAALAADHLVSAHIAHNRKK
NT seq 963 nt   +upstreamnt  +downstreamnt
atggctactgttgaaggatgtttggttgccagtactcacagaggttgcaaggccctttcc
agttcttttgaaggaggtgtaaacagcgtcattttgagcgacggaatgactagaggtcca
gttgttcaatttgccaacacaaagagatgtaacgagcttaaacaattcattgataatcca
gaaaatttcaaggaattatgtagagtttttaacagtgattctcgttttgctagattgttg
gaagttaaagttggtattgctggtagaaaggcattcttgagattcaagtgccgaactggt
gatgctatgggaatgaacatgatttcaaaagcaacacaaaaggctcttaaattcttgaag
aatgaacacttccaagatatggacattttaagtttgagtggtaactattgtacagataag
aagccatcagcaatgaattggattgaaggtagaggtaaatccgttgttgttgatgctacc
attccaaaggatgttgtgaagaatgttcttaagactacagttgatgaaattgtcagtctc
aatatatctaagaatttaattggtagtgctatggctggttctgttggtggtttcaacgct
catgctgccaatatcgtgacagcaatctttttggctactggtcaagatgctgcccaaaat
gtggaaagctcgaattgtatgactattatggaaaagactgataatggtgatttatatgtc
tctgtgacaatgccatctattgaagtaggtacagttggtggtggtactcacttggatgct
caaaagacttgtttgaagattattggtgttgctggtgcaaaccaagaaaatccaggtcaa
aatgctcaaacccttgccaaatgtgttgctagtactgtaatggctggagaactttctctc
atggctgctcttgctgctgatcacttggtgtctgctcatattgctcacaacagaaagaag
taa

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