Neorickettsia helminthoeca: NHE_0452
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Entry
NHE_0452 CDS
T03076
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase family protein
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
nhm
Neorickettsia helminthoeca
Pathway
nhm00300
Lysine biosynthesis
nhm00550
Peptidoglycan biosynthesis
nhm01100
Metabolic pathways
nhm01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
nhm00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
NHE_0452 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
NHE_0452 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
NHE_0452 (murF)
Enzymes [BR:
nhm01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
NHE_0452 (murF)
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
LpxD
Motif
Other DBs
NCBI-ProteinID:
AHX11396
UniProt:
X5H4A2
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All DBs
Position
complement(398440..399846)
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AA seq
468 aa
AA seq
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MILTPNLIRSVLKAEVISKYDVRIDISKSRFSIDSRTIEKGEIFIAIKGERCDAHTFIES
AYLNGASAIITRKHLECPELAIPIIKVDDPVAAMQKLATMLIREYQPIVIGITGSNGKTT
SKEFTAALLRNYGETHCNAGNLNSLIGLPLSVLNTDFPCKFLVLEMGMLHHGDIDLLNRI
ALPKVTIITNIGSAHIKFLGSQEAIALEKAKIFQNGCPVVLNPNAPYSDLLIERAKESNS
TILSFGEGKDCDIKLLDYSNSRVSIEIYGARYTYQFPNYGLHFVYDSLAAIGVAKALELD
ITNELLENTFSTFQPSKGRGEHHNFSIDGKKITVIDDTYNANYESISALIKYVQSTYSDM
RVITIIGSIGDMGERAEEFYRKLAERVGSLESLILIGTDKISILKESLANSVALYADVDE
LINNFYRDHPLTQDTVIAIKGSRFMNLEKFVQHIIAKADQLLPLESIS
NT seq
1407 nt
NT seq
+upstream
nt +downstream
nt
atgattctcactccaaacctcatcagaagcgtattaaaagcagaagtaatatcaaagtat
gatgtaaggatcgatatttcgaagagcagattttccatagacagtaggactatagaaaag
ggtgaaatattcattgcaatcaagggtgagaggtgtgatgcgcatactttcatagaatct
gcttatctgaatggagcatcagcgatcatcaccagaaagcatcttgaatgtccagaatta
gcgattcccattatcaaggtcgatgatccggttgcagcaatgcagaaattagctactatg
cttataagagagtaccaacctatcgtcataggtatcaccggtagtaatgggaaaaccact
tcgaaggaattcactgcagccttgttaagaaactatggagaaacgcattgtaatgcgggt
aatttgaatagcctgatcggtctaccattgagcgttctcaatactgatttcccatgtaaa
tttcttgttctagaaatgggaatgctacatcatggagatatagacctactaaatcggata
gccttaccgaaggtcaccattataacaaatattggttctgcccacataaagtttctagga
tcgcaagaagctatagcactcgaaaaagctaaaatatttcaaaatggatgcccggtagta
cttaatcccaatgcaccctacagtgatctactcatagaaagggcgaaagaaagcaattcg
accatcttatcatttggtgaagggaaagactgtgatatcaaattgcttgactattcaaac
agcagagtttctattgaaatatatggtgctagatatacatatcaatttcctaattatgga
ttacacttcgtgtatgatagcttagctgcgataggagtggcaaaggcattggagttagat
atcacaaatgagttactagagaacactttctcgacttttcagccatcgaagggtagaggc
gagcatcacaatttcagtatagacggcaaaaagatcactgtaatagatgatacatacaat
gcaaactatgaatccatctcagcgctgattaaatatgttcaatccacctattcggatatg
agggtaataacaatcattggctcgattggtgatatgggagaaagagcagaggaattctat
agaaaactcgccgaaagagtgggatcactggaatccctaatacttataggaacagataag
atatctatactcaaggaaagcttagcaaatagtgtagctctctatgctgatgtggatgag
ttaatcaataatttttatagagatcatccgctgactcaggatactgttatagcaataaag
ggatcacgctttatgaatcttgaaaaattcgtacagcacataatagcgaaagcagatcaa
ctgttaccactcgaatcaatctcctag
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