Nocardia huaxiensis: H0264_16515
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Entry
H0264_16515 CDS
T07784
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
nhu
Nocardia huaxiensis
Pathway
nhu00300
Lysine biosynthesis
nhu00550
Peptidoglycan biosynthesis
nhu01100
Metabolic pathways
nhu01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
nhu00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
H0264_16515
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
H0264_16515
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
H0264_16515
Enzymes [BR:
nhu01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
H0264_16515
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
QLY33619
UniProt:
A0A7D6ZKT2
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Position
3710347..3711855
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AA seq
502 aa
AA seq
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MIEMTLREIADIVGGTLHDVPDPEAKVTGTVEFDSRRVDSGDLFLALPGERVDGHEFAAG
AVDKGAVAVLAARPVGVPAVVVAPRPHASRAIALAHDADGSGAAVLDALAKLARVSVDRL
VAAGGLTVVGVTGSSGKTSTKDLLAAVLAPLGEVVAPPGSFNNELGHPWTALRADADTRF
LVLELSARGPGHIKALTEIAPPSVGVVLNVGTAHLGEFGTQEVIAQTKGELVEALPPTGL
AVLNLDDHLVAKMAQRTRARVVTVGLNSNADVRATDVSLDEQARARFTLYHRGESVDIRL
AVHGEHQVGNALSAAAVALDQGADLATVAQALSGASAVSARRMDVRTRADGVTVVNDSYN
ANPDSVRAALKALVTMARAGGADGQSPVSVHRRSWAVLGEMGELGEESVLEHDRIGRLVV
RLDVDQLVVVGAGRPVRAMFQGAVQEGSWGEEAIHVPDISSAIALLDQELAPGDVVLVKA
SKSVGLWAVAEHLTGAAEEAAR
NT seq
1509 nt
NT seq
+upstream
nt +downstream
nt
atgatcgagatgactctgcgggagatcgcggacatcgtgggcggcacgctccacgatgtt
cccgaccccgaggcgaaggtcaccgggacggtcgaattcgattcgcgccgtgtcgattcg
ggtgacctgttcctggcgctgccgggcgagcgcgtggacggccacgagttcgccgcgggc
gctgtcgacaagggcgctgtcgcggtgctggccgcgcggcccgtgggcgttccggccgtc
gtggtcgcgccgcgcccgcacgccagccgcgcgatcgcgctggcccacgatgccgacggc
tccggcgcggccgtgctggacgcgctggcgaaactcgctcgggtgagcgtggatcggctc
gtcgcggccggtgggctcaccgtggtcggcgtgaccggatcctccggcaagacctccacc
aaggacctgctggcagccgtcctcgccccgctgggagaggttgtggcgccgccgggttcg
ttcaacaacgaactcgggcatccgtggacggccctgcgcgccgatgccgacacccgattc
ctggtactggagctgtccgcgcgcggaccgggacatatcaaggcgctcaccgagatcgcc
ccgcccagtgtcggcgtcgtgctgaatgtcggcaccgcgcacctcggcgagttcggcacc
caggaggtcatcgcgcagaccaaaggcgaactggtggaagcgcttccgccgaccggcctg
gccgtgctcaatctcgacgatcacctggtcgccaagatggcgcagcgcacgcgggcccgc
gtggtgaccgtcggcctcaactcgaacgccgatgtgcgcgccaccgacgtcagcctcgac
gagcaggcgcgggcgcgattcacgctgtaccacaggggcgagagcgtcgacatccggctg
gccgtgcacggtgagcaccaggtcggcaatgcgctctcggccgcggccgtggccctcgat
cagggggcggatctcgccaccgtcgcgcaggcgctgtccggcgcgtccgccgtgtcggcc
cgccgcatggatgtgcgcacgcgcgccgatggcgtcaccgtcgtcaacgactcctacaac
gccaacccggattcggtgcgtgcggcgctcaaggcgctggtcaccatggcgcgcgccgga
ggcgctgatgggcagagcccggtgtcggttcatcgccgcagctgggcggtgctcggcgaa
atgggcgagctgggtgaggaatccgtgctcgagcacgatcgcatcggccgcctggtggtg
cgcctggatgtggatcagctcgtggtcgtcggcgcgggccgtccggtgcgcgccatgttc
cagggcgcggtgcaggagggctcgtggggtgaggaggccatccatgttccggatatctcc
tcggccatcgccttgctggatcaggaactcgcacccggcgatgtggtgctggtgaaagcg
tccaagtccgtggggctctgggctgtcgccgagcacctgaccggtgccgccgaggaggcc
gctcgatga
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