Nocardia iowensis: KV110_09545
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Entry
KV110_09545 CDS
T07470
Name
(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
nie
Nocardia iowensis
Pathway
nie00790
Folate biosynthesis
nie01100
Metabolic pathways
nie01240
Biosynthesis of cofactors
Module
nie_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
nie00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
KV110_09545
Enzymes [BR:
nie01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
KV110_09545
6.3.2.17 tetrahydrofolate synthase
KV110_09545
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Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
QXN95426
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Position
2105363..2106769
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AA seq
468 aa
AA seq
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MSSGPSPVELAEMALVEAELDTRWPETKIEPSLSRIATLMDLLGSPQQSYPAIHVAGTNG
KTSVTRMIDALLTALHRRTGRITSPHLQLATERISIDNAPITPARYVETYRELQPFIEMI
DTQSAAAGGPAMSKFEVLTGMAFAAFAEAPVDVAVVETGMGGTWDATNVIDGQVAVITPI
GLDHTDYLGTDLAAIAGEKAGIIKRAPESLIPRDTVAIIAEQDPEAMEVLLRRAVEVDAA
VAREGGEFRVLARQIAIGGQQLELQGLGGVYDEIFLPLHGEHQARNAVLALAAVEAFFGA
GADRQLDIEAIRAGFASVTSPGRLERMRSAPTIFIDAAHNPAGAQALASTLTAEFDFRKL
VGVVAVLADKDADGILTALEPVLDEIVVTGNGSPRAMDVDMLADLAVQRFGDERVITAPT
LPDALETAIAIAEEVGEAGEMVSGAGVVVTGSVVTAGATRALFGKDPA
NT seq
1407 nt
NT seq
+upstream
nt +downstream
nt
ctgagttccgggccgtcgccggtcgagctggccgaaatggctttggtggaagccgaactc
gatacccgctggccggaaaccaagatcgagccctcgctcagccggatcgccaccctgatg
gacctgctcggctcgccgcagcagagctacccggcgatccatgttgcgggcaccaacggc
aagacctcggtgaccaggatgatcgacgcactgctcaccgcactgcaccggcgcaccggc
cggatcaccagcccgcacctgcagctggccaccgagcggatcagcatcgacaacgcgccg
atcacgcccgcccggtatgtcgagacctaccgcgaactgcagccgttcatcgagatgatc
gacacgcagtcggcggcggcgggcggtccggcgatgagcaagttcgaggtgcttaccggc
atggccttcgcggccttcgccgaggcgccggtcgacgtcgccgtcgtggagaccggcatg
ggcggcacctgggacgcgaccaatgtcatcgacgggcaggtcgcggtgatcaccccgatc
ggcttggaccacaccgactacctcggcaccgatctcgccgccatcgcgggcgagaaggcc
ggcatcatcaaacgcgcgccggagagcctcattccgcgcgacaccgtcgcgatcatcgcc
gaacaggaccccgaggcgatggaggtgctgctgcgccgcgccgtcgaagtagacgcggcg
gtggcgcgcgaaggcggcgaattccgggtgctggcccggcagatcgcgatcggtggccag
cagctcgaactgcagggcctcggcggggtatacgacgagatcttcctgccgctgcacggc
gagcatcaggcgcgcaacgcggtgctcgccctcgcggcggtcgaggcgttcttcggcgcc
ggtgccgaccggcagctcgacatcgaggccatccgtgcgggtttcgcgagcgtgaccagt
ccgggccggctcgagcggatgcgcagcgcgccgaccatcttcatcgacgccgcgcataac
ccggcgggcgcgcaggcgcttgcctcgacgttgaccgcggagttcgacttccgcaagctg
gtcggggtggtcgcggtgctggccgacaaggacgcggacgggatcctcaccgcgctcgaa
ccggtgctcgacgaaatcgtcgtcaccggcaatggttcgccgcgcgcgatggacgtcgac
atgctcgccgatctcgcggtacagcgcttcggcgacgaacgggtgatcaccgcgccgacc
ctgccggacgcgctggagaccgccatcgccatcgccgaggaggtcggcgaggcaggggag
atggtgtccggtgccggggtcgtggtgaccggctcggtggtgacggcgggcgcgacgcgc
gcgctcttcggaaaggacccagcgtga
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