Nocardia iowensis: KV110_11730
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Entry
KV110_11730 CDS
T07470
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
nie
Nocardia iowensis
Pathway
nie00300
Lysine biosynthesis
nie00550
Peptidoglycan biosynthesis
nie01100
Metabolic pathways
nie01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
nie00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
KV110_11730
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
KV110_11730
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
KV110_11730
Enzymes [BR:
nie01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
KV110_11730
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Paralog
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
QXN93678
UniProt:
A0ABX8RVK4
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Position
2550241..2551755
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AA seq
504 aa
AA seq
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MIEMTLREIADVVGGTLHDVPDPEVRVTGSAEFDSRRVGSGDLFLALPGARSDGHDYAAA
AVAAGAVAVLAARPVGVPAIVVTPSPGLVPSSSVALAADSDGSGAAVLAALAALARVSVE
RLTAAGTLTVVGVTGSSGKTSTKDLLAAVLDPLGPVVAPPGSFNNELGHPWTALRANADT
RFLVLEMSARGTGHIAALAEVAPPSIGVVLNVGTAHLGEFGSREAIAKAKGELVEALPAS
GLAVLNADDPQVAAMASRTSARVVTVGQSDNADVRATDIRLDDQARAGFTLHTSVGSSPI
HLAVHGEHQVGNALAAVAVALECGADLDTIARSLSDARAASARRMDVRTTARGVTVVNDS
YNANPDSVRAALKALVTMSRAGETPRRSWAVLGEMGELGEESVVEHDRIGRLAVRLDVHR
LVVVGTGRPSRAMHQGAVMEGSWGEESILVPDIGAAIALLDDEVEAGDVVLVKASKSVGL
WEVAEHLIGTEPPSGRQGSTEAFE
NT seq
1515 nt
NT seq
+upstream
nt +downstream
nt
atgatcgagatgacactgcgggagatcgcggacgtcgtcggcggcacgctgcacgacgtc
cccgacccggaggtccgggtgaccggttcggccgaattcgattcgcgccgagtcggttcc
ggcgatctgttcctggcattgccgggtgcgcgatcggacggccacgactacgccgccgcg
gcggtggcggccggtgcggtcgcggtgctcgcggcccgcccggtgggtgtgcccgccatc
gtcgtcacgccgagccccggcctggtgccgtcgagttcggttgccctggcggcggattcg
gacggctccggagccgcggtgctcgccgcgctcgccgccttggcccgggtcagcgtcgaa
cgcctcaccgcggcgggaactctcaccgttgtcggggtgaccggctcatccggtaagacc
tcgaccaaggacctgctcgcggccgtgctggacccgctcgggccggtcgtcgccccgccg
ggctcgttcaacaacgagctcggccatccctggacggcgttgcgcgccaatgccgacacc
cgtttcctggtgttggagatgtccgcgcgcggcaccggccatatcgccgcgctcgccgag
gtcgcgccgccgagcatcggcgtcgtgctcaatgtcggcaccgcccatctcggtgagttc
ggcagccgcgaggccatcgccaaggccaaaggcgaactggtggaggcgcttccggcgtcc
gggctggccgtgctgaatgccgacgacccgcaggtcgccgcgatggcgtcgcggacatcg
gcccgcgtggtcaccgtcggacaatccgacaacgccgatgtgcgggccaccgatatccgg
ctcgacgaccaagcacgcgcggggttcaccctgcacacctcggttggcagcagcccgatc
cacttggccgtgcacggcgaacatcaggtcggcaatgcgcttgccgcggtggcggtcgcc
ctcgagtgcggcgcggacctcgacaccatcgcgcggtcgctgtccgacgcccgcgccgcc
tccgcgcgccggatggatgtacgcaccaccgcgcgcggcgtgaccgtcgtcaacgactct
tacaacgccaatccggattcggtccgcgcggccctgaaggcgctggtcaccatgtcgcgc
gcgggcgaaaccccgcgccgcagctgggcggtgctcggcgaaatgggcgagctcggtgaa
gaatccgtggtcgaacacgaccggatcggacggctcgcggtgcggctcgacgtgcaccgg
ctggtcgtcgtcggcaccggaaggccgtcccgggcgatgcatcagggagcggtgatggaa
ggctcatggggcgaggagtcgatcctcgtgcccgacatcggcgcggccatcgcgttgctc
gacgacgaagtcgaggcgggtgatgtggtgctggtcaaggcatcgaagtcggtgggcctc
tgggaggtcgccgaacacttgatcggtacagagccacccagcggacgccagggaagcacg
gaggccttcgagtga
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